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Wedbush initiated coverage on Solid Biosciences, Inc. SLDB , a gene therapy company focused on treating Duchenne muscular dystrophy (DMD). DMD is a genetic disease that causes progressive muscle weakness and wasting. SGT-003 is the leading program in Solid Biosciences' pipeline, with plans to advance additional projects toward clinical trials in 2025. The therapy uses the AAV-SLB101 capsid and a specialized cargo (nNOS binding domain) to potentially boost dystrophin expression compared to earlier-generation treatments. While first-generation gene therapy for Duchenne muscular dystrophy (DMD) opens new treatment possibilities, there is still room for improvement. The analyst writes that Solid Biosciences' innovative approach and novel capsid technology could enhance microdystrophin delivery. Although the company's pipeline offers multiple opportunities, current projections focus only on SGT-003 for DMD. The most significant near-term milestone for Solid Biosciences is the initial Phase 1/2 INSPIRE DUCHENNE trial results, expected in the first quarter of 2025. Approving Sarepta Therapeutics Inc's SRPT Elevidys was a key milestone in treating Duchenne muscular dystrophy (DMD), but it's only the beginning. Newer treatments with better and more reliable results are still needed. Wedbush analyst writes, "We see Solid Biosciences in a "solid" position to deliver a next-gen therapeutic option." Wedbush writes that Solid Biosciences' stock trade at around $5 each, with about $4 per share in cash providing some downside protection. Assuming Solid Biosciences' SGT-003 program follows a timeline similar to Sarepta's Elevidys, even a one-year delay would lower the price target to $11 per share (current price target of $16)—still above the current trading price. With other programs yet to be included in the valuation, the analyst sees strong potential and initiates with an Outperform rating . Solid Biosciences ended the third quarter of 2024 with approximately $171.1 million in cash, cash equivalents, and available-for-sale securities, with an anticipated cash runway into 2026. Price Action: SLDB stock is up 3.21% at $4.83 at the last check on Friday. Read Next: Gilead Unveils New Yearly HIV Injection To Offer Hope for Less Frequent Preventive Dosing © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.Where to watch WWE Friday Night Smackdown FREE STREAM today (12/13/24)
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When Jimmy and Rosalynn Carter entered the White House in 1977, they became the first couple since John F Kennedy to raise their children in the executive mansion on Pennsylvania Avenue. Over the years, their family continued to grow in size, with nearly two dozen grandchildren and great-grandchildren added to the Carter clan. “We have a big family now. We have 22 grandchildren and great-grandchildren, 38 of us in all,” Carter told CNN in 2015. “So, we try to hold our family together and just enjoy the family life.” Rosalynn passed away in November 2023. Carter became the longest-living president when he turned 98 in October 2022. He died at the age of 100 on Sunday, December 29, his son announced. An immediate cause was not given. “It’s been awe-inspiring to watch my grandfather live out his values for all these decades,” his grandson Jason Carter told People in a previous interview. “My earliest memories are from his years in the White House, and I’ve grown up witnessing and learning from his faith and his belief in equal treatment and respect for all people." In February 2023, Carter entered hospice care following multiple hospital stays. He celebrated his 100th birthday on October 1, 2024, joining his loved ones in the backyard of his home to watch a military flyover in his honor. His grandson Jason said he is also looking forward to voting for Kamala Harris in the November election. Here’s what we know about the Carters’ children: John William “Jack” Carter, 77, is the eldest son of Jimmy and Rosalynn Carter. He spent his young adult years at the Georgia Institute of Technology, but later left to join the US Navy and served during the Vietnam War. He would eventually be discharged after he was caught smoking marijuana while stationed in Idaho, but he would later rejoin Georgia Tech and earn a degree in nuclear physics. Like his father, Mr Carter also had a stint in US politics, winning the Democratic primary for the US Senate in Nevada in 2006, but he lost the general election to Republican John Ensign. His top issues during the campaign were opposing the Iraq War and improving healthcare, particularly for veterans. “We took our eye off Afghanistan, which should have been the focus,” he said during a campaign stop with his father, according to the Tahoe Daily Tribune. James Earl “Chip” Carter III, 74, the second eldest son, was handed down his father’s and grandfather’s name. He had a son with his first wife Caron Griffin, whom he also bestowed the name upon. He worked in the family peanut warehouse for a while before he was elected to the Plains City Council and worked on the Democratic National Committee. Jimmy Carter revealed in the documentary Jimmy Carter: Rock & Roll President that Chip and singer Willie Nelson smoked marijuana on the White House roof. “When Willie Nelson wrote his autobiography, he confessed that he smoked pot in the White House one night when he was spending the night with me,” Mr Carter said in the documentary. “And he says that his companion that shared the pot with him was one of the servants in the White House. That is not exactly true — it actually was one of my sons, which he didn’t want to categorize as a pot-smoker like him.” Donnel “Jeff” Carter, 72, is the youngest of the Carter brothers. He studied geography and computer cartography and later co-founded the company Computer Mapping Consultants with his former professor the same year he graduated, he told Time magazine. He had three children, Joshua, Jeremy, and James, but Jeremy passed away in 2015 at the age of 28 from an apparent heart attack . Donnel lost his wife Annette, 68, in 2021. He met her on their first day of school at Georgia Southwestern State University. Joshua Carter wrote in an obituary for his mother that “Jeff saw her across the student center while he was playing spades, and he told his friends to turn around and look at that pretty girl that just walked in. He told them he was going to marry her, and four years later he did.” They were married for 46 years. Amy Carter, 57, is the only daughter and youngest child by 15 years of the former president and first lady. Ms Carter spent her childhood years in the White House while her father was serving as president, putting her in the political and media spotlight at a young age. Born in October 1967, she was nine years old when her father became president. She later went on to become known for her political activism, such as participating in protests and sit-ins against US foreign policy in Central America and apartheid in South Africa. On one occasion in 1986, Ms Carter and several others were arrested during a protest against CIA recruitment. She was acquitted of charges of disorderly conduct and trespassing, according to The New York Times. She illustrated her father’s children’s book, The Little Baby Snoogle-Fleejer , which was published in 1995. Ms Carter has two sons from two marriages. In more recent years, she has kept a low profile. She became a member of the Carter Center Board of Councilors in 2020.
( MENAFN - GetNews) Popular drummer and Instagram sensation Tora Drums has announced the release of her debut single in 2025, sending her fans into a frenzy. Born Khuat Hoa Xuan in Hanoi, Tora Drums is considered a Vietnamese powerhouse who already boasts over 87,000 subscribers on her YouTube channel and has shown technical prowess and undeniable passion for her craft. Her ground-breaking compositions have the potential to completely transform the rhythmic landscape. Since she started playing the drums in 2017, Tora has been progressively advancing her career. Over the course of her remarkable seven-year journey, the drummer from Hanoi has already put out five original compositions, including instrumentals that highlight her technical prowess and variety. In her senior year of high school, Tora's passion for drumming was ignited on the bustling streets of Hanoi, where her narrative began. Tora remembers, "It came very naturally to me." There weren't many musicians in my hometown at the time. I fell in love with drums because I wanted to study something artistic. She soon turned her love of rhythm into a lifetime endeavor. Tora committed herself to endless hours of practice, pushing the limits of her craft despite the lack of resources and opportunities in her village. She eventually created a distinctive style that captivates audiences all around the world by fusing emotional depth with technical accuracy. Her debut album marks an important turning point in Tora's career. Although the album's specifics are being kept under wraps, fans can anticipate a selection of songs that combine her distinctive drumming with avant-garde compositions. The CD attempts to highlight Tora's diversity and reinterpret what drumming may be in modern music, ranging from soulful rhythms to high-energy beats. Through her YouTube channel, Tora Drums, which has over 87,000 subscribers, and Instagram account, @toradrums , Tora has established a robust online community. Fans may observe her creative process, take in captivating performances, and establish a personal connection with her journey through her platforms. Her videos, which feature everything from drum covers to original songs, have won accolades for their inventiveness and technical mastery. Beyond the screen, Tora has worked with other musicians, which has strengthened her standing as a creative and adaptable performer. Tora's debut album release is only the first step. She intends to tour with her songs, perform live at locations throughout Vietnam and abroad, and release the album. Along with her own identity as a musician, fans can anticipate new original songs, artist collaborations, and interesting brand partnerships. According to Tora, "I want to continue developing as an artist and use my music to reach more people." "This album is only the beginning of what I want to accomplish." For the latest updates, follow Tora Drums on Social Media. Instagram: YouTube: @toradrum MENAFN23122024003238003268ID1109025410 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.
Chris Cenac Jr., the top center in the Class of 2025 according to the ESPN100, has committed to play for the Houston Cougars. The five-star recruit announced his decision Tuesday via the Bleacher Report's B/R App. Cenac previously said he wouldn't make his decision until the spring, but his stock soared over the summer after his impressive play on the Puma Pro 16 circuit with Dallas-based YGC, vaulting him into the national top-10 rankings. The 6-foot-10 New Orleans native was reportedly choosing between LSU, Auburn, Arkansas, Baylor, Kentucky, Tennessee and others before making the decision to join Cougars coach Kelvin Sampson's team. "I just like the coaching staff a lot, I like their plan to develop me and I like coming into a winning program," Cenac told 247Sports. "I'm looking forward to producing and just helping them win more. But the main thing was development and them being able to get me better so I can be ready for that next level." Cenac's rating of .9978 by 247Sports Composite makes him the Cougars' highest-rated commit in the modern era, according to multiple outlets. "They see me as a four who can kind of play all over the court and do everything," Cenac told 247Sports. "I can get rebounds, push the ball, shoot and play all over the floor." With Cenac joining other Houston commits like five-star shooting guard Isaiah Harwell, four-star point guard Kingston Flemings and three-star wing Bryce Jackson, Houston's Class of 2025 is ranked No. 2 in the nation by 247Sports and ESPN. --Field Level MediaJimmy Carter: A brief bioTop US Securities Regulator To Exit, Clearing Way For Trump Pick
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( MENAFN - EIN Presswire) Christmas Gifts Bring Holiday Cheer with splendid Champagne Gifts for Christmas Celebrations VIENNA, VA, UNITED STATES, December 13, 2024 /EINPresswire / -- As the festive season approaches, the tradition of exchanging meaningful gifts is taking center stage, with champagne emerging as a popular choice for celebrating Christmas. Known for its timeless appeal and celebratory nature, champagne is becoming a favored gift option for friends, family, and business associates during the holidays. This growing trend highlights the appeal of curated champagne gift sets, such as the Veuve Clicquot Gifts and the Moët & Chandon Gifts, which pair premium champagne with gourmet treats and elegant accessories. These thoughtful combinations elevate the act of gifting, making the experience as memorable as the champagne itself. The Veuve Clicquot Gift Set , for example, combines the brand's renowned champagne with a selection of flutes and gourmet chocolates, creating a complete festive package. Known for its vibrant flavors and rich history, Veuve Clicquot embodies the spirit of celebration. Another alternative that serves as the best Christmas gifting piece includes a Moët & Chandon gift basket . The gift basket comes along with a bottle of luxurious Moët & Chandon renowned globally for its fruity and toasty flavors that pairs wonderfully with the chocolaty delights like cookies, truffles and brownies that is an addition in the gift basket. The tradition of gifting champagne extends beyond individual bottles to include unique options like hand-painted champagne bottles and Mimosa gift baskets, which combine champagne with fruit juice and festive snacks. These gifts cater to morning celebrations and brunch gatherings, adding a touch of elegance to early-day festivities. For those seeking convenience, online platforms such as Wine & Champagne Gifts provide a wide selection of champagne gift options, including personalized sets and curated baskets. These platforms are gaining recognition for their ability to deliver high-quality champagne gifts paired with gourmet delicacies and premium glassware. This growing preference for champagne gifts reflects a broader shift toward thoughtful and celebratory presents during the holiday season. Whether it's a classic bottle, a curated gift basket, or a set enhanced with festive accessories, champagne gifts offer a timeless way to spread cheer. Last-minute gift baskets can be a reliable and thoughtful option, offering a variety of combinations to suit different preferences. Many providers specialize in pairing champagne with gourmet snacks and elegant accessories, making it easier to find a meaningful gift during the busy holiday season. Wishing you a joyous and memorable holiday celebration! For More Gift Ideas Take reference From Below: blog/best-champagnes-to-give-as-a-gift/ blog/best-champagne-brands-for-every-celebration/ blog/best-champagnes-for-christmas-gifts/ blog/best-champagne-under-budget-100/ Charu Smith Wine And Champagne Gifts +1 202-459-8489 email us here Visit us on social media: Facebook X LinkedIn Instagram YouTube Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above. MENAFN13122024003118003196ID1108991961 Legal Disclaimer: MENAFN provides the information “as is” without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the provider above.Yankees’ Aaron Judge wins second AL MVP Award after historic 2024 seasonCam Akers reached down in front of him to scoop a sinking pass from Sam Darnold, bringing it into his body as he tumbled backwards. As he did, two words ran through his mind: game over. Akers’ late catch, which came with less than two minutes left in the game on a third-and-2 pass, sealed a 27-25 win for the Vikings over the Green Bay Packers on Sunday afternoon in a game at U.S. Bank Stadium that got tight late. ADVERTISEMENT “I’m blessed,” Akers said. “On my journey from where I’ve come from, to be able to be in there, crunch time, fourth quarter, the coaches trust me, the team trusts me,” Akers said. “I’m blessed.” It’s been a long journey for the running back, who has dealt with two serious Achilles injuries in previous seasons. But Akers, now in his second stint with the Vikings, has rewarded the coaching staff for its faith in him. He also caught a 9-yard touchdown pass late in the third quarter, one which ended up proving the difference in the win. His opportunities on Sunday came in part because Aaron Jones took a shot to the quad earlier in the game, which he played through before watching the end of the game from the sidelines. His last carry in the game came near the end of the third quarter. “Coach was like, ‘Hey, we’re going to hold you for a little bit,’ but I was good,” Jones said. “I kept warm just in case they needed me. Kept my helmet on.” They didn’t wind up needing him, thanks in large part to Akers. “Cam has something inside him that allowed him to push through the adversity of what’s happened to him over the course of his career,” coach Kevin O’Connell said. “His teammates were probably the most excited all season when Cam scored on that screen and then obviously the catch late. He just brings something. He brings physicality. He brings a level of mental and physical toughness that I think makes us all better.” ADVERTISEMENT Nailor gets Vikings going Darnold aired it out and found his receiver, on the run, open in the end zone. It wasn’t Justin Jefferson, nor Jordan Addison, but Jalen Nailor, who hauled in the 31-yard pass for the Vikings’ first touchdown of the game. “I just had a post route. I’ve seen the far safety. He wasn’t there,” Nailor said. “I just took off running as fast as I could and Sam found me.” Darnold found Nailor a season-high five times on Sunday. He finished the day with 81 yards, also a season-high, and his touchdown was his first in more than a month, with the last one coming in the Vikings’ Nov. 24 win over the Bears. “It just felt good to be out there, just help the team win,” Nailor said. “That’s all I’m trying to do.” O’Connell’s belief in Reichard “sky high” Will Reichard’s first field goal attempt Sunday hit the crossbar. The rookie kicker missed a 55-yard attempt near the end of the first half, but a Green Bay penalty negated his miss and a subsequent Packers’ timeout took away a 50-yard make. He then connected from 50 yards to send the Vikings into halftime up 10. His last field goal attempt of the day went off the left upright from 43 yards. But despite a shaky day, O’Connell’s confidence in the 23-year-old, who also converted on a short kick in the second quarter, hasn’t wavered. ADVERTISEMENT “I just told him, ‘Hey, next one’s going to be the best one.’ My confidence in Will is sky high,” O’Connell said of Reichard. “If we think we’re anywhere near the range, I’m going to give him the swing. He’s a phenomenal kid, great makeup. The next kick’s going to be his best kick.” ______________________________________________________ This story was written by one of our partner news agencies. Forum Communications Company uses content from agencies such as Reuters, Kaiser Health News, Tribune News Service and others to provide a wider range of news to our readers. Learn more about the news services FCC uses here .
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NoneLottery player has hard time believing huge win is real in Michigan. ‘Amazing feeling’Shares of Nvidia fell over 2% in midday trading on Friday, diverging from a broader rally in semiconductor stocks led by Broadcom’s milestone entry into the trillion-dollar valuation club. Nvidia’s drop followed the U.S. Supreme Court’s decision to dismiss the company’s appeal in a lawsuit alleging it misled shareholders about its reliance on cryptocurrency mining revenue leading up to the 2018 market crash. The semiconductor bellwether has faced additional pressure this week with shares declining nearly 4% amid anti-trust investigations by Chinese and European authorities. This slump has caused the company to lose its position as the world's most valuable chipmaker, now trailing Apple and Microsoft in market capitalization rankings - but retail sentiment remains optimistic. The lawsuit in question accuses Nvidia and its CEO, Jensen Huang, of violating the 1934 Securities Exchange Act. It alleges the company made false or misleading statements about how much of its revenue was driven by sales to cryptocurrency miners during the crypto boom of 2017-2018. When mining profitability collapsed in 2018, Nvidia's revenue fell short of expectations, triggering a sharp drop in its stock price of nearly 28% in two days, resulting in significant losses for investors. At the time, Huang said a “crypto hangover” was to blame. The Supreme Court dismissal came weeks after justices questioned whether the case presented broad legal implications warranting their intervention. “I’m not actually sure what rule we could articulate that would be clearer than our cases already say,” Justice Sonia Sotomayor said during the Nov. 13 argument. Despite the market being bearish on Nvidia, retail sentiment around the stock has improved to ‘bullish’ from ‘neutral’ a day ago along with an uptick in chatter to ‘high’ levels. Investors on Stocktwits remain hopeful that the current decline is merely a temporary correction, with expectations of a rebound. This marks the second securities fraud case the Supreme Court has declined to hear within the past two months. In a similar move last month, the court rejected an appeal by Meta Platforms Inc., which now faces allegations of misleading shareholders over its role in the data-harvesting controversy involving Cambridge Analytica. Nvidia remains one of the year's top-performing stocks, boasting a 176% gain year-to-date despite recent setbacks. For updates and corrections, email newsroom[at]stocktwits[dot]com.< Read also: Broadcom Joins Trillion-Dollar Club Driving Marvell, Astera, And Other Chip Stocks To Record Highs: Retail Is Doubling Down
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