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Teesside Park: Every new brand to open in 2024 - and what's coming next year
Ryan Bertrand opens up on life after football as former Champions League winner turns himself into successful businessman
Rico Carty, who won the 1970 NL batting title when he hit a major league-best .366 for the Atlanta Braves, has died. He was 85. Major League Baseball , the players’ association and the Braves paid tribute to Carty on social media on Sunday. A family friend told Listín Diario — a newspaper in Carty’s native Dominican Republic — that he died Saturday night in an Atlanta hospital. “Carty was one of the first groundbreaking Latino stars in the major leagues, and he established himself as a hero to millions in his native Dominican Republic, his hometown of San Pedro de Macoris, and the city of Atlanta, where he was a beloved fan favorite,” the players' association said in its statement . The Braves said Carty left an indelible mark on the organization. “While his on-field accomplishments will never be forgotten, his unforgettable smile and generous nature will be sorely missed,” the team said in its statement. Carty made his big league debut with the Braves in September 1963. He batted .330 with 22 homers and 88 RBIs in his first full season in 1964, finishing second to Dick Allen in voting for NL Rookie of the Year. The Braves moved from Milwaukee to Atlanta after the 1965 season, and Carty got the franchise's first hit in its new home on April 12, 1966, against Pittsburgh. Carty had his best year in 1970, batting .366 with 25 homers and a career-best 101 RBIs. He started the All-Star Game after he was elected as a write-in candidate, joining Willie Mays and Hank Aaron in the NL outfield. Carty batted .299 with 204 homers and 890 RBIs over 15 years in the majors, also playing for Cleveland, Toronto, Oakland, Texas and the Chicago Cubs. He retired after the 1979 season. AP MLB: https://apnews.com/hub/MLB
WOBURN, Mass., Nov. 21, 2024 (GLOBE NEWSWIRE) -- Replimune Group, Inc. (NASDAQ: REPL), a clinical stage biotechnology company pioneering the development of novel oncolytic immunotherapies, today announced that it has submitted a biologics license application (BLA) to the FDA for RP1 (vusolimogene oderparepvec) in combination with nivolumab for the treatment of adult patients with advanced melanoma who have previously received an anti-PD1 containing regimen. The submission was made under the Accelerated Approval pathway. The Company also announced that the FDA has granted Breakthrough Therapy designation to RP1 in combination with nivolumab in the same setting. Breakthrough Therapy designation is intended to expedite the development and review of therapies for serious diseases when preliminary clinical evidence indicates that the therapy may provide substantial improvement over existing available therapies on one or more clinically significant endpoints. This Breakthrough Therapy designation is based on the safety and clinical activity observed in the anti-PD1 failed melanoma cohort of the IGNYTE clinical trial. "Today is an important milestone for Replimune and for the melanoma community as we are one step closer to having another potential treatment available for patients who have limited options after progressing on anti-PD1 containing regimens,” said Sushil Patel, Ph.D., CEO of Replimune. The confirmatory Phase 3 IGNYTE-3 trial of RP1 in combination with nivolumab in advanced melanoma patients who have progressed on anti-PD1 and anti-CTLA-4 therapy, or who are not candidates for anti-CTLA-4 treatment is currently enrolling patients. For more information, visit https://replimune.com/clinical-trials/ignyte-3/ . About RP1 RP1 (vusolimogene oderparepvec) is Replimune's lead product candidate and is based on a proprietary strain of herpes simplex virus engineered and genetically armed with a fusogenic protein (GALV-GP R-) and GM-CSF, intended to maximize tumor killing potency, the immunogenicity of tumor cell death, and the activation of a systemic anti-tumor immune response. About Replimune Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of novel oncolytic immunotherapies. Replimune's proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com . Forward Looking Statements This press release contains forward looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, including statements regarding our belief regarding the effect that the breakthrough designation will have on the timing and development of RP1 and other statements identified by words such as "could,” "expects,” "intends,” "may,” "plans,” "potential,” "should,” "will,” "would,” or similar expressions and the negatives of those terms. Forward-looking statements are not promises or guarantees of future performance, and are subject to a variety of risks and uncertainties, many of which are beyond our control, and which could cause actual results to differ materially from those contemplated in such forward-looking statements. These factors include risks related to our limited operating history, our ability to generate positive clinical trial results for our product candidates, the costs and timing of operating our in-house manufacturing facility, the timing and scope of regulatory approvals, the availability of combination therapies needed to conduct our clinical trials, changes in laws and regulations to which we are subject, competitive pressures, our ability to identify additional product candidates, political and global macro factors including the impact of the coronavirus as a global pandemic and related public health issues and the Russian-Ukrainian and Israel-Hamas political and military conflicts, and other risks as may be detailed from time to time in our Annual Reports on Form 10-K and Quarterly Reports on Form 10-Q and other reports we file with the Securities and Exchange Commission. Our actual results could differ materially from the results described in or implied by such forward-looking statements. Forward-looking statements speak only as of the date hereof, and, except as required by law, we undertake no obligation to update or revise these forward-looking statements. Investor Inquiries Chris Brinzey ICR Healthcare 339.970.2843 [email protected] Media Inquiries Arleen Goldenberg Replimune 917.548.1582 [email protected]
Surat Businessman Attacks Family, Then Attempts Suicide; Wife and Minor Son Murdered, Parents Injured
NYPD recovers DNA with manhunt for CEO's killer dragging onJanuary in the Garden for Central FloridaWhat to consider when exchanging currencyWith the girls basketball season set to start next week, here is a look at the state’s divisional alignments in each of the 15 conferences for the 2024-25 season. Burlington County Scholastic League Freedom Division Bordentown Burlington City Burlington Township Maple Shade Moorestown Friends Palmyra Pennsauken Tech Independence Division Doane Academy Florence KIPP Cooper Norcross Academy Riverside STEMCivics Willingboro Liberty Division Cinnaminson Holy Cross Prep Thrive Charter Westampton Tech Patriot Division Delran Medford Tech Northern Burlington Pemberton Pennsauken Big North Conference American Division Cliffside Park Dumont Dwight-Morrow Fort Lee Ridgefield Park Freedom Division Hackensack Northern Highlands Paramus Ramapo Ridgewood Independence Division Fair Lawn Lakeland Passaic Valley Wayne Hills Wayne Valley West Milford Liberty Division Bergen Tech Clifton Passaic Passaic Tech Paterson Eastside Paterson Kennedy National Division Bergenfield Demarest Old Tappan Pascack Valley Teaneck Tenafly Patriot Division Indian Hills Mahwah Pascack Hills Ramsey River Dell Westwood United Division DePaul Holy Angels Immaculate Heart Paramus Catholic Cape-Atlantic League American Division Absegami Atlantic City Holy Spirit Mainland Middle Township Our Lady of Mercy Wildwood Catholic National Division Cedar Creek Egg Harbor Hammonton Lower Cape May Millville Ocean City Vineland United Division Atlantic Tech Bridgeton Buena Cape May Tech Oakcrest Pleasantville St. Joseph (Hamm.) Colonial Conference Liberty Division Haddon Heights Haddon Township Haddonfield Sterling West Deptford Woodbury Patriot Division Audubon Collingswood Gateway Gloucester Lindenwold Paulsboro Colonial Valley Conference Colonial Division Ewing Hightstown Hopewell Valley Notre Dame Nottingham Princeton Robbinsville Trenton Valley Division Allentown Hamilton West Lawrence Princeton Day Steinert West Windsor-Plainsboro North West Windsor-Plainsboro South Greater Middlesex Conference Blue Division Carteret Dunellen Highland Park Iselin Kennedy Metuchen Sayreville South River Timothy Christian Gold Division Calvary Christian (Old Bridge) East Brunswick Magnet Mother Seton New Brunswick Perth Amboy Magnet Piscataway Magnet Somerset Tech South Amboy Wardlaw-Hartridge Woodbridge Magnet Red Division Colonia East Brunswick Monroe North Plainfield Old Bridge Piscataway South Brunswick St. Thomas Aquinas White Division Edison J.P. Stevens Middlesex North Brunswick Perth Amboy South Plainfield Spotswood Woodbridge Hudson County Interscholastic Athletic League American Division Bayonne Hudson Catholic Kearny St. Dominic Union City National Divison Hoboken Lincoln Memorial North Bergen Snyder Patriot Division BelovED Charter Dickinson Ferris McNair University Charter Northwest Jersey Athletic Conference American Division Chatham Mendham Montville Morristown Pope John Randolph Colonial Division Dover Hopatcong Kittatinny Newton Sussex Tech Wallkill Valley Freedom Division Hackettstown High Point Jefferson Lenape Valley North Warren Vernon Independence Division Boonton Kinnelon Parsippany St. Elizabeth Villa Walsh Whippany Park Liberty Division Hanover Park Madison Morris Catholic Morris Tech Morristown-Beard Mountain Lakes Pequannock National Division Morris Hills Morris Knolls Mount Olive Parsippany Hills Roxbury Sparta West Morris North Jersey Interscholastic Conference Independent Saddle River Day American Division Elmwood Park Garfield Lodi Manchester Regional Paterson Charter Saddle Brook Colonial Division Butler Eastern Christian Glen Rock Hawthorne Hawthorne Christian Pompton Lakes Liberty Division Bogota Dwight-Englewood Leonia New Milford Palisades Park Ridgefield Meadowlands Division Becton Hasbrouck Heights St. Mary (Ruth.) Wallington Wood-Ridge National Division Harrison Lyndhurst North Arlington Rutherford Secaucus Weehawken Patriot Division Cresskill Emerson Boro Midland Park Park Ridge Waldwick Olympic Conference American Division Cherokee Cherry Hill East Eastern Lenape Rancocas Valley National Division Bishop Eustace Camden Camden Catholic Camden Eastside Paul VI Patriot Division Cherry Hill West Moorestown Seneca Shawnee Winslow Super Essex Conference American Division Glen Ridge Montclair Immaculate Mount St. Dominic Newark Academy University West Orange Colonial Division Bloomfield Cedar Grove East Orange Montclair North Star Academy Verona Freedom Division Arts Barringer Belleville Irvington Newark Collegiate Science Park St. Benedict’s Weequahic Independence Division Livingston Millburn Montclair Kimberley Newark East Side Newark Lab Newark Tech Liberty Division Caldwell Columbia Newark Central Nutley Payne Tech West Essex National Division Bard Golda Och Orange Shabazz St. Vincent Technology West Caldwell Tech West Side Shore Conference A Central Division Howell Jackson Memorial Manasquan Neptune St. Rose Wall A Coastal Division Holmdel Middletown North Red Bank Catholic Red Bank Regional Rumson-Fair Haven St. John Vianney A North Division Colts Neck Marlboro Ocean Township Ranney Shore Trinity Hall A South Division Central Regional Donovan Catholic Manchester Township Southern Toms River East Toms River North B Central Division Brick Memorial Jackson Liberty Lakewood New Egypt Point Pleasant Beach Point Pleasant Boro B Coastal Division Henry Hudson Keansburg Keyport Matawan Middletown North Raritan B North Division Asbury Park Freehold Borough Freehold Township Long Branch Manalapan Monmouth B South Division Barnegat Brick Township Lacey Pinelands Toms River South Skyland Conference Delaware Division Franklin Gill St. Bernard’s Hillsborough Hunterdon Central Phillipsburg Rutgers Prep Mountain Division Belvidere Bernards Bound Brook Manville South Hunterdon Raritan Division Mount St. Mary Pingry Ridge Voorhees Warren Hills Watchung Hills Valley Division Bridgewater-Raritan Delaware Valley Immaculata Montgomery North Hunterdon Somerville Tri-County Conference Classic Division Clayton Gloucester Catholic Pitman Salem Salem Tech Wildwood Diamond Division Glassboro Overbrook Penns Grove Schalick Woodstown Liberty Division Cumberland Delsea Deptford Highland Timber Creek Triton Royal Division Clearview Gloucester Tech Kingsway Washington Township Williamstown Union County Conference Mountain Division Dayton Gov. Livingston Johnson Oak Knoll Roselle Summit Union Catholic Valley Division Brearley Hillside Kent Place Linden Rahway Roselle Park Union Watchung Division Cranford Elizabeth New Providence Plainfield Roselle Catholic Scotch Plains-Fanwood Westfield RECOMMENDED • nj .com Final Group 2 boys soccer season stat leaders for 2024 Dec. 3, 2024, 1:19 p.m. Final Group 3 boys soccer season stat leaders for 2024 Dec. 3, 2024, 1:20 p.m. Lauren Knego may be reached at lknego@njadvancemedia.com . Follow her at @laurenknego The N.J. High School Sports newsletter now appears in mailboxes 5 days a week. Sign up now! Follow us on social: Facebook | Instagram | X (formerly Twitter )
TPG RE Finance Trust, Inc. Declares Cash Dividend on Series C Cumulative Redeemable Preferred Stock
Russian security chief meets Taliban officials in KabulEU rules requiring all new smartphones, tablets and cameras to use the same charger came into force on Saturday, in a change Brussels said will cut costs and waste. Manufacturers are now obliged to fit devices sold in the 27-nation bloc with a USB-C, the port chosen by the European Union as the common standard for charging electronic tools. "Starting today, all new mobile phones, tablets, digital cameras, headphones, speakers, keyboards and many other electronics sold in the EU will have to be equipped with a USB Type-C charging port," the EU Parliament wrote on social media X. The EU has said the single charger rule will simplify the life of Europeans and slash costs for consumers. By allowing consumers to purchase a new device without a new charger, it will also reduce the mountain of obsolete chargers, the bloc has argued. The law was first approved in 2022 following a tussle with US tech giant Apple. It allowed companies until December 28 this year to adapt. Makers of laptops will have extra time, from early 2026, to also follow suit. Most devices already use these cables, but Apple was more than a little reluctant. The firm said in 2021 that such regulation "stifles innovation", but by September last year it had begun shipping phones with the new port. Makers of electronic consumer items in Europe had agreed on a single charging norm from dozens on the market a decade ago under a voluntary agreement with the European Commission. But Apple, the world's biggest seller of smartphones, refused to abide by it and ditch its Lightning ports. Other manufacturers kept their alternative cables going, meaning there were about half a dozen types knocking around, creating a jumble of cables for consumers. USB-C ports can charge at up to 100 Watts, transfer data up to 40 gigabits per second, and can serve to hook up to external displays. At the time of its approval, the commission said the law was expected to save at least 200 million euros ($208 million) per year and cut more than a thousand tonnes of EU electronic waste every year. "It's time for THE charger," the European Commission wrote on X on Saturday. "It means better-charging technology, reduced e-waste, and less fuss to find the chargers you need." ub/givPublished 23:59 IST, December 28th 2024 CPI(M) MLA's Son Caught With Ganja, Legislator Dismisses Allegations As Baseless Alappuzha: U Pratibha MLA denied the reports that her son was arrested with ganja on Saturday after the officials of the excise department arrested nine people for possessing the narcotics. Her son also rejected the allegations on social media. The Kayamkulam MLA on Facebook Live alleged that her son was only questioned when he was sitting with his friends, adding that the media was haunting her. "Since the news broke, I have been receiving many phone calls," she said. "When my son and friends were sitting together, the Excise officers came and asked questions, but the news came that my son was caught with ganja," she said. "If the news is true, I will apologise. If not, the media should apologise publicly," the MLA added. The Excise Department said that they have arrested nine people, including the son of CPI(M) MLA U Prathibha, with ganja from Thakazhi in Kuttanad in Alappuzha district. According to the officers, all nine were released on bail. "We seized ganja from a member of the group from under Thakazhi bridge. They were arrested for smoking and possessing weed. Since it was a small quantity, all were released on bail,” an Excise officer added. A case was registered and an investigation is underway. Get Current Updates on India News , Entertainment News along with Latest News and Top Headlines from India and around the world. Updated 23:59 IST, December 28th 2024
Apple's journey toward replacing Qualcomm's modems in iPhones is a big leap in its quest for self-reliance. The company has been developing its own modems—codenamed Sinope, Ganymede, and Prometheus—for years. The first of these, Sinope, is expected to , though it won't match Qualcomm's high-end offerings in speed or performance. Specifically, it will use Sub-6 5G technology, which delivers good coverage but lacks the ultra-fast speeds of mmWave 5G, like the 10 Gbps downloads seen in Qualcomm's modems in devices like the iPhone 16 Pro. The iPhone SE itself is also shaping up to be an exciting entry point for this modem. While details about its other features remain under wraps, the SE line typically borrows designs and hardware from previous premium iPhones. If Apple follows its usual playbook, this , but now with Apple's own modem tech baked in. This isn’t Apple's first time dropping a longtime supplier to create its own solutions. Apple’s shift toward self-reliance is exemplified by the M1 chip, , which revolutionized Mac performance and efficiency while phasing out Intel processors. However, this transition began long before, with Apple acquiring ARM architecture expertise and building a foundation that eventually delivered a chip capable of transforming Mac performance and efficiency. Over the next few years, Apple updated every Mac model with its silicon, showcasing its commitment to controlling core technologies. By designing its own modems, Apple could unlock several benefits. It gains tighter integration between hardware and software, which is something the company excels at, and potentially reduces costs over time. Owning the modem technology also gives Apple the flexibility to innovate and tailor features without being reliant on Qualcomm's roadmap. Apple laid the groundwork for this effort by , gaining critical expertise and resources. However, it's not been an easy journey. Reports suggest that Apple's modem prototypes still trail Qualcomm's in performance, particularly in efficiency and global compatibility, which explains the cautious rollout starting with the SE. Apple's roadmap also reveals ambitions beyond Sinope. In 2026, the Ganymede modem is expected to expand the in-house solution to more models, followed by Prometheus in 2027. Meanwhile, Apple has extended its deal with Qualcomm to 2027, ensuring a fallback plan during this gradual transition. Source:A new year is a time for new beginnings. And that applies as much to your personal finances as anything else. As we hail the start of 2025, Newsweek asked personal finance experts: What is the one thing Americans should stop doing with their money? Bola Sokunbi, Author/Founder & CEO, Clever Girl Finance I absolutely have to say using credit cards as a backup emergency fund. It's a slippery slope, and the interest can delay or even completely derail your long-term goals. In 2025, let's focus on building a real emergency fund—aim for at least three months' worth of expenses. Also, stop comparing your finances to someone else's Instagram life. Most of it's fake anyway—remember your journey is yours alone! Tiffany Aliche, Founder, The Budgetnista; Author, Get Good with Money Stop doing Buy Now, Pay Later! On the surface, it sounds like a good idea, but it encourages you to finance literally everything. You go from just having a car bill and mortgage bill to suddenly having a "lamp bill" and a "couch bill". Everything you buy is now being financed and your spending is completely out of sync. Do yourself a favor and switch to a Save Now, Pay Later mindset! Michael Krowe, Director, Financial Planning, Edelman Financial Engines Americans need to stop putting pressure on themselves to become homeowners. Homeownership can be wonderful, but it isn't for everyone—especially if it would create more financial strain than benefit. I find I'm having more and more conversations with my clients (and their adult kids) on this very topic. Although there are many advantages to purchasing a home, renting has its own benefits. For starters, buying a home typically requires a significant amount of cash for down payment and closing costs. How about home repairs, maintenance, and upkeep? Or property taxes? Not to mention homeowner association fees. Renters do not face these hurdles. We would advise you not to buy a home if you plan to move within five to seven years. It simply isn't worth the hassle, let alone the cost. Carolyn McClanahan, Founder, Life Planning Partners; Advisor, CNBC Financial Advisor Council Quit trying to find the next best investment and especially stay away from speculative investments with your retirement savings. Retirement savings need to be put in a diversified portfolio of low-cost passive investments. Kyla Scanlon, Economic Commentator; Author, "In This Economy?" Stop using Buy Now, Pay Later. It makes things feel frictionless, but it fragments the financial picture and makes true spending harder to track. Andy Smith, Executive Director, Financial Planning, Edelman Financial Engines People need to stop focusing on the little things and start focusing on the bigger, more strategic things that can help make a meaningful difference. For example, forgoing a fancy coffee drink a couple times each week isn't going to get you to your retirement goals. But contributing to your employer's 401k plan will help you do that, and that includes taking advantage of the different features your plan has to offer, such as saving enough to receive the company match, or opting into auto-escalation so you don't forget to increase your savings each year. Or, maybe you've levered up on debt because you wanted to purchase a vacation home, but instead you could have done some long-term renting for your holidays and saved yourself the headaches and the expense of owning a second property. Or, perhaps your adult children are still living with you at home, draining your retirement savings because they weren't focused on a career path in college that would help make them more marketable and financially independent. These are the types of things to focus on versus the little things. Eric Tyson, Best-Selling Author of Personal Finance For Dummies and Investing For Dummies If you're not able to regularly save a modest amount of your earnings, you need to pay off your consumer debt as soon as possible. I also recommend not getting stock and other investment tips from social media. Kelli Smith, Director, Financial Planning, Edelman Financial Engines In 2025, people should stop buying things they don't need or cannot afford. A large number of people overspend and under save. That creates a lifestyle they won't be able to afford by the time they reach retirement age. Instead, come up with a savings plan to make sure retirement and other financial goals are being fully funded, then spend what's left. Elaine King, Founder and CEO, Family and Money Matters Rather than what to stop, here's what to start: Question the source of your financial advice. For example, are you trusting a chocolate company to guide your health or a nutritionist with no ties to a product? The same applies to finance—ask yourself: "What's the monetary benefit for the person giving me advice?" In 2025, focus on advisors who prioritize your financial education and empowerment, not their own incentives. Investing in financial literacy could be your smartest move yet.
NoneTwo PUNCH journalists, Olugbon Saheed and Segun Odunayo, have been nominated for the 2024 Journalists of the Year Award by the Africa Media Development Foundation. They are shortlisted for the photo and print categories, respectively. They are among the 11 finalists that made the list. The AMDF award which recognises outstanding journalism that has made a significant impact on development issues across Africa, covers various media categories — photo, print, online, television and radio journalism, according to a statement issued on Friday by the Executive Director, AMDF, Sekyen Dadik. “The finalists, chosen from a highly competitive pool of submissions, have demonstrated exceptional skill, dedication and commitment to reporting on critical issues that affect the continent,” the statement partly read. Finalists for the 2024 AMDF Journalist of the Year Award include: Photo Category: • Ayodele Isaac — The Nation Newspaper, Nigeria. • Olugbon Saheed — The Punch Newspaper, Nigeria. Print Category: Related News PUNCH journalists shine at Africa media awards Lagos policemen torture PUNCH journalists for covering #EndSARS protests PUNCH journalists shine at WAMECA awards • Nyima Sillah — The Voice Newspaper, Gambia. • Segun Odunayo — The Punch Newspaper, Nigeria. • Taiwo Alimi — The Nation Newspaper, Nigeria. Online Category: • Abdulraheed Hammad — The Cable, Nigeria. • Arinze Chizioke — Ripples Nigeria. • Kei Duku — One Citizen Newspaper, South Sudan. Television Category: • Adeyemi Adekunle — Lens Africa TV, Nigeria. • Chernor Mustapha — Apex Multi-Media Co-op, Sierra Leone. • Ibrahim Ismail — Trust TV, Nigeria. However, the statement noted that none of the entries in the radio category met the minimum required standard outlined in the call for entry. The winners and runners-up will be announced during the Africa Conference on Development Journalism, which will be held from December 4-5, 2024, in Kaduna State, Nigeria. The event will also bring together journalists, media professionals and stakeholders to discuss the role of journalism in driving development and social change in Africa. “We are incredibly proud of all the finalists and their contributions to journalism. Their work exemplifies the importance of holding powerful interests to account and shedding light on critical issues that impact our communities,” Dadik said.