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Nearly half of US teens are online 'constantly,' Pew report findsScheifele scores winner as Jets beat Blackhawks 4-2 in Sorensen's debutBeacon Technology Market to Witness Excellent Revenue Growth Owing to Rapid Increase in Demand 12-14-2024 12:05 PM CET | Advertising, Media Consulting, Marketing Research Press release from: AMA Research & Media LLP Beacon Technology Advance Market Analytics published a new research publication on "Global Beacon Technology Market Insights, to 2030" with 232 pages and enriched with self-explained Tables and charts in presentable format. In the Study, you will find new evolving Trends, Drivers, Restraints, Opportunities generated by targeting market-associated stakeholders. The growth of the Beacon Technology market was mainly driven by the increasing R&D spending across the world. Major players profiled in the study are: BlueCats (Australia), BlueSense (United Kingdom), Estimote (United States), Accent Systems (Spain), GeLo (United States), Glimworm Beacons (Netherlands), Gimbal (United States), Kontakt.io (United States), Sensorberg (Germany), Sonic Notify (United States) Get Free Exclusive PDF Sample Copy of This Research @ https://www.advancemarketanalytics.com/sample-report/58323-global-beacon-technology-market?utm_source=OpenPR&utm_medium=Vinay Scope of the Report of Beacon Technology Beacon technology is a wireless transmitter that uses low energy Bluetooth technology to send signals to other smart devices. The beacon technology majorly used as location-based technology. This market is reaching a maturity point in the United States majorly in the retail sector. In technical aspects beacons are getting major attraction in contrast to other solutions, it is used for both proximity detection and location estimation. This market has strong growth potential due to the high development in IoT technology. In Oct 2018, Selexis SA announced the acquisition of Berkeley Lightâ€TMs Beacon optofluidic platform. Through this agreement, the Selexis accelerate the cell line development of its platform. The titled segments and sub-section of the market are illuminated below: by Application (Indoor positioning and Navigation, Retail, Employee attendance and tracking, Facilities Management, Logistics and Transport, Healthcare, Others (Payments, Healthcare)), Deployment Mode (On-Premise, Cloud), Platforms (IBeacon, Eddystone, AltBeacon) Market Opportunities: •Increase number of hypermarket create strong opportunity for beacon provider to track customers in-store environment •Increase demand from the banking sector for providing personalized product offering, branch analytics, and others • Market Drivers: •Increase the penetration of internet of things across the globe •Increase demand for customizing IT infrastructure •Technology or modernization or retail sector •Rising demand for Personalized Shopping Experience on Mobile Devices • Market Trend: •Advancement of the beacon with artificial technology •Increase adoption of beacon technology for a cross-channel and omnichannel shopping experience • What can be explored with the Beacon Technology Market Study? •Gain Market Understanding •Identify Growth Opportunities •Analyze and Measure the Global Beacon Technology Market by Identifying Investment across various Industry Verticals •Understand the Trends that will drive Future Changes in Beacon Technology •Understand the Competitive Scenarios -Track Right Markets -Identify the Right Verticals Region Included are: North America, Europe, Asia Pacific, Oceania, South America, Middle East & Africa Country Level Break-Up: United States, Canada, Mexico, Brazil, Argentina, Colombia, Chile, South Africa, Nigeria, Tunisia, Morocco, Germany, United Kingdom (UK), the Netherlands, Spain, Italy, Belgium, Austria, Turkey, Russia, France, Poland, Israel, United Arab Emirates, Qatar, Saudi Arabia, China, Japan, Taiwan, South Korea, Singapore, India, Australia and New Zealand etc. Get Up to 30% Discount on This Premium Report @ https://www.advancemarketanalytics.com/request-discount/58323-global-beacon-technology-market?utm_source=OpenPR&utm_medium=Vinay Strategic Points Covered in Table of Content of Global Beacon Technology Market: Chapter 1: Introduction, market driving force product Objective of Study and Research Scope the Beacon Technology market Chapter 2: Exclusive Summary - the basic information of the Beacon Technology Market. Chapter 3: Displaying the Market Dynamics- Drivers, Trends and Challenges & Opportunities of the Beacon Technology Chapter 4: Presenting the Beacon Technology Market Factor Analysis, Porters Five Forces, Supply/Value Chain, PESTEL analysis, Market Entropy, Patent/Trademark Analysis. Chapter 5: Displaying the by Type, End User and Region/Country 2016-2022 Chapter 6: Evaluating the leading manufacturers of the Beacon Technology market which consists of its Competitive Landscape, Peer Group Analysis, BCG Matrix & Company Profile Chapter 7: To evaluate the market by segments, by countries and by Manufacturers/Company with revenue share and sales by key countries in these various regions (2024-2030) Chapter 8 & 9: Displaying the Appendix, Methodology and Data Source Finally, Beacon Technology Market is a valuable source of guidance for individuals and companies. Read Detailed Index of full Research Study at @ https://www.advancemarketanalytics.com/buy-now?format=1&report=58323?utm_source=OpenPR&utm_medium=Vinay Thanks for reading this article; you can also get individual chapter wise section or region wise report version like North America, Middle East, Africa, Europe or LATAM, Southeast Asia. Contact Us: Craig Francis (PR & Marketing Manager) AMA Research & Media LLP Unit No. 429, Parsonage Road Edison, NJ New Jersey USA - 08837 Phone: +1(201) 7937323, +1(201) 7937193 sales@advancemarketanalytics.com About Author: Advance Market Analytics is Global leaders of Market Research Industry provides the quantified B2B research to Fortune 500 companies on high growth emerging opportunities which will impact more than 80% of worldwide companies' revenues. Our Analyst is tracking high growth study with detailed statistical and in-depth analysis of market trends & dynamics that provide a complete overview of the industry. We follow an extensive research methodology coupled with critical insights related industry factors and market forces to generate the best value for our clients. We Provides reliable primary and secondary data sources, our analysts and consultants derive informative and usable data suited for our clients business needs. The research study enables clients to meet varied market objectives a from global footprint expansion to supply chain optimization and from competitor profiling to M&As. This release was published on openPR.
NASA has again postponed the return to Earth of Barry Wilmore and Sunita Williams, the astronauts stranded on the International Space Station after Boeing's Starliner capsule malfunctioned in the middle of this year. The crew of the spacecraft arrived at the ISS in June. The objective was to test the Starliner’s comprehensive capabilities, including launch, docking, and return systems. The mission was scheduled to last one week. Five of the capsule’s 28 thrusters failed to function before docking with the ISS. Boeing claimed that its technology could guarantee the safe return of the astronauts. However, NASA expressed doubts and concluded that the risk was too high. The agency entrusted the task to SpaceX . Elon Musk's company launched the Crew-9 mission in September to, among other things, return Williams and Wilmore. Until now, the stalled astronauts were scheduled to return in February aboard the Crew Dragon rocket. However, NASA has announced that it expects the expedition to return to Earth's surface after the arrival of Crew-10, which will be sent in late March 2025 at the earliest. The adjustment will allow SpaceX and NASA engineers to finalize development of a new Dragon spacecraft, which will be shipped to the company's Florida facility early next month. "Fabrication, assembly, testing, and final integration of a new spacecraft is a painstaking endeavor that requires great attention to detail,” said Steve Stich, manager of NASA’s Commercial Crew Program, in a statement. “We appreciate the hard work by the SpaceX team to expand the Dragon fleet in support of our missions and the flexibility of the station program and expedition crews as we work together to complete the new capsule’s readiness for flight.” NASA said that Crew-9 and Crew-10 crews must complete a “handover period,” during which the ISS residents share experiences and knowledge with the new arrivals. This process ensures the proper performance of onboard science experiments and maintenance of the orbital complex. NASA and SpaceX specialists evaluated several options for coordinating the next crewed delivery. They determined that the March launch for Crew-10 was the “best option for meeting NASA’s requirements and achieving space station objectives for 2025,” according to an agency press release. A Long Haul The ISS received two resupply flights in November, ensuring that the crew members have sufficient food, water, clothing, and oxygen. However, some experts have warned of potential health risks for Wilmore and Williams after spending more than nine months in space. The scientific community has been studying the effects of spaceflight on the human body since the 1970s. In the years since the first lunar landing, it has identified conditions such as loss of bone mass, weakened heart function, visual problems, and the development of kidney stones. A recent study from University College London reveals that the structure and function of the kidneys can also suffer permanent damage, although this is particularly aggressive in cases of astronauts who get too far away from Earth, which is not the case on the ISS. NASA points out that the crews of expeditions to the ISS usually make extended stays, with an average duration of six months. It adds that some astronauts have carried out missions of up to one year to contribute to research on human adaptation to spaceflight, with a view to future lunar and Martian exploration. This story originally appeared on WIRED en Español and has been translated from Spanish.
ASHBURN, Va. (AP) — When Dan Quinn left the Dallas Cowboys after three years as their defensive coordinator to coach the Washington Commanders, it looked as if he was leaving a perennial playoff contender for a rebuilding project. Instead, Quinn's Commanders are in the thick of the playoff race even after consecutive losses provided something of a speed bump, while the Cowboys' season has fallen apart . Dallas (3-7) visits Washington (7-4) on Sunday in a franchise role reversal for the NFC East rivals. "For me and for the guys, man, it’s Washington-Dallas Week, let’s get down," Quinn said. “I don’t make one (game) too often bigger than another. I just think they’re all really important, and we absolutely go after it as hard as we can.” Quinn, defensive coordinator Joe Whitt Jr. and a handful of former Dallas players have been part of Washington's turnaround, including pass rusher Dante Fowler, defensive end Dorance Armstrong, center Tyler Biadasz and receiver Noah Brown, who famously caught rookie quarterback Jayden Daniels' Hail Mary toss for the game-winning touchdown last month to beat Chicago . Armstrong has followed the Cowboys' downfall since leaving in free agency, saying simply, “It’s not good.” And that was before a piece of their stadium's roof fell Monday night before their fifth consecutive loss , a 34-10 blowout by Houston . Injuries, including starting QB Dak Prescott's torn hamstring that led to season-ending surgery, have been the backdrop for Dallas' forgettable year. Coach Mike McCarthy, who's approaching the end of his contract and possibly his tenure, said he and his staff are “going to stay the course” and play who's available. That means Cooper Rush again getting the nod in place of Prescott, though McCarthy said a package of plays could open up to get 2021 No. 3 pick Trey Lance into the game. “Cooper’s been there for a little minute, so he knows the system really good," said Fowler, who leads the Commanders with 8 1/2 sacks. "Trey Lance is really good with his legs, and he’s a dynamic quarterback, as well. You don’t want to go out there half-stepping against those guys because they do play good football, as well.” The Commanders have played far better football than the Cowboys so far this season, so much that the home team is a 10 1/2-point favorite on BetMGM Sportsbook. Washington has never been more than a nine-point favorite against Dallas in any game going back to at least 2003, according to BetMGM. The Cowboys could get a bit of a spark with the anticipated return of receiver Brandin Cooks, who has seen way too much sorrow around him since he last played in Week 4. “Get guys playing at a high level, playing fun, playing free, and having a great time out there,” Cooks said. “That’s what I’m not seeing right now. I think we can go out there and be more joyful in our process.” There's plenty of joy in Washington, with the playoffs still on the line, unlike Dallas. “It’s definitely cool to be in that type of position rather than being on the other side," Fowler said. “Just cool to see what Coach Quinn has just done since he came here with this team and getting a group of guys to come together and play as one.” A rib injury knocked Daniels out of a rout of Carolina on Oct. 20, and while he did not miss a game, the 23-year-old has not been as dangerous or effective since. The No. 2 pick out of LSU and reigning Heisman Trophy winner has completed 59.5% of his passes the past four games after 75.6% before getting injured, and he has had his average rushing yards cut nearly in half from 53.1 to 27.5. Quinn insists Daniels is not injured and pinned the regression on a lack of practice time in recent weeks. Daniels also said he's good to go after some extra rest following a 26-18 loss at Philadelphia on Thursday, Nov. 14. “The mini bye, I think it just helps everything, just to reset your mind and get ready for the second half of the season,” Daniels said. “I was able to reset and refocus, restart.” The offensive line has been a problem all season for the Cowboys. Now it’s a major injury concern. Perennial All-Pro right guard Zack Martin and promising young left guard Tyler Smith sustained ankle injuries on the same drive in the fourth quarter for the Cowboys against the Texans. Martin, who is also dealing with a shoulder issue, is doubtful. Smith is questionable while also working through a knee injury. T.J. Bass and Brock Hoffman were the replacements at guard against the Texans. The Cowboys could start four linemen 25 or younger, although veteran tackle Chuma Edoga could make his season debut. Edoga was the projected starter at left tackle before injuring a toe in training camp. He is listed as questionable. “With Zack, he’s a keystone for our offensive line," McCarthy said. "That will be a big one. But it’s more opportunity for these young players who haven’t played a lot and are getting a lot of work." McCarthy said the Cowboys “took a step backward, clearly” running the ball against Houston after making progress the previous couple of games. Rico Dowdle, now the clear lead back after ineffectiveness and off-field drama from Ezekiel Elliott, had just 28 yards on 10 carries, and the Cowboys finished with 64 yards. They allowed 141 yards, including 109 and three touchdowns by Joe Mixon, and have the NFL's second-worst rushing defense. Washington's Brian Robinson Jr. has already set a career high with seven TD runs and could be in for a lot of carries. “I look forward to running the ball any time,” Robinson said. “I’m prepared, I’m ready and if it happens like that, I’m ready for it." AP Pro Football Writer Schuyler Dixon in Frisco, Texas, contributed. AP NFL: https://apnews.com/hub/nfl
Viasat Completes Sale of Energy Services Systems Integration BusinessFermentation is turning microalgae into a sustainable superfood, delivering health breakthroughs like diabetes management and paving the way for greener, healthier diets. Review: Exploring the Potential and Challenges of Fermentation in Creating Foods: A Spotlight on Microalgae . Image Credit: Chokniti-Studio / Shutterstock In a recent review published in the journal Fermentation , researchers in Brazil explored the challenges and potential of using fermentation processes involving microalgae to produce nutritious, sustainable, and safe foods. They concluded that microalgae fermentation holds promise to support the development of healthy foods, including those with antioxidant, anti-inflammatory properties, and anti-diabetic properties, but called for consumer education to facilitate wider commercialization and acceptance. Fermentation in food production Fermentation is a naturally occurring metabolic process in which microorganisms, including fungi, yeast, or bacteria, convert sugars into simpler compounds by producing energy anaerobically or without oxygen. It is widely used in industrial and biological processes. Microalgae are photosynthetic powerhouses that produce nearly half of the Earth's oxygen while efficiently converting carbon dioxide into biomass, making them a vital player in combating climate change. Interest is growing in the applications of fermentation in food production, focusing on creating sustainable and nutritious foods using microalgae. Recent studies demonstrate that fermentation produces bioactive peptides with dipeptidyl peptidase-4 (DPP-IV) inhibition, which can improve insulin sensitivity and glucose regulation. Microalgae fermentation produces several beneficial metabolites, including volatile compounds, organic acids, and bioactive peptides, that enhance food's health benefits, nutritional value, aroma, and flavor. For example, antioxidant activity during microalgae fermentation is linked to phenolic compounds, which reduce oxidative stress and support metabolic health. Studies show that fermenting Spirulina can enhance antioxidant properties and regulate blood glucose levels. Bioactive peptides, for example, improve insulin sensitivity and help regulate glucose levels in the blood. This presents opportunities for foods that protect against disease and provide nutrition. However, microalgae-based foods face challenges related to consumer acceptance due to sensory factors. The fermentation process Microalgae are grown in restricted environments where nutrients, light, and temperature are carefully controlled before harvesting. Microorganisms and substrates are introduced to initiate the fermentation process. Submerged fermentation involves using liquid media to optimize scaling and nutrient control, while solid-state fermentation involves minimal water use and reduces the risk of contamination. Microalgae proteins are a game-changer: They offer an alternative to traditional animal proteins, acting as thickening agents and stabilizers in food products, which could transform the food industry. Fermentation improves nutrient absorption, introducing beneficial microorganisms that promote gut health. These processes also enhance the bioavailability of microalgal pigments like phycocyanin and carotenoids, which contribute to antioxidant and health-protective effects. For example, bioactive peptides found in these foods are known to support antioxidant activity, immune function, diabetes management, and cardiovascular health. Key studies have shown that fermenting Spirulina improves antioxidant activity, supporting glucose regulation, while fermenting Undaria and Sachharina increases antioxidant and antidiabetic activity. For Ulva and Sargassum seaweed, the fermenting process inhibited alpha-amylase, which prevented spikes in blood glucose. The process also develops unique aromas and flavors, which may increase acceptance of certain products. For example, fermentation using Kluyveromyces marxianus introduces floral and fruity notes, while lactic acid bacteria reduce undesirable earthy flavors. It may be used to create alternative protein sources for vegans and vegetarians, enhancing the sustainability of food production and reducing environmental impacts from land use. Fermentation and consumer perception The fermentation process modifies the texture and flavor of microalgae, offering possibilities for the food industry. Studies on various strains of yeast show that fermented Saccharomyces cerevisiae has fruity, milky, and cheesy notes. At the same time, Kluyveromyces marxianus imparts soap-like and floral flavors, and Debaryomyces hansenii introduces fruity and acidic notes. Lactic acid bacteria and Bacillus strains reduce undesirable earthy flavors and add unique flavors, respectively. Specifically for dairy products, adding Spirulina in yogurt can improve texture and odor acceptance, but higher concentrations may impart an unpalatable aftertaste. In probiotic yogurts, even distributions of Spirulina can improve palatability and acceptability. Similarly, Spirulina has been shown to enhance the texture and taste of crackers, crostini, and bread. Microalgae biodiversity is vast: There are an estimated 200,000 to 800,000 species of microalgae, but only about 50,000 have been described, leaving enormous untapped potential for innovation in food and biotechnology. However, despite their established nutritional benefits, microalgae are not commonly used in food, and how consumers perceive fermented microalgae food products remains inconsistent and dynamic. The growing interest in healthy and sustainable foods is offset by low consumer acceptance due to unfamiliarity. Sensory profiles strongly impact consumer perception. The strong odors, colors, and flavors introduced by pigments like chlorophyll, as found in powdered Spirulina, have an intense taste and may reduce appeal. Recent research emphasizes that transparent labeling and sustainability certifications can significantly improve consumer trust and willingness to try these products. Educating consumers on the benefits of microalgae may overcome these challenges, as a lack of awareness about the health benefits may hinder acceptance. In addition to health benefits, many consumers may view the sustainability and environmental benefits of microalgae favorably. Microalgae uses less water and land than the production of meat while absorbing greenhouse gases. Cultivating them can also use wastewater, conserving increasingly scarce freshwater resources, but production costs may be high. Large-scale production also faces challenges in ensuring efficient nutrient use and minimizing ecological impacts, such as land use changes or potential disruptions to local habitats. Awareness can be created through transparent and informative labeling, as studies have shown that consumers value clear information on sustainable and safe production practices. To build consumer trust, strict research and monitoring of environmental and food safety concerns are also required. Conclusion Current research suggests that microalgal fermentation produces bioactive peptides, which can lead to significant health benefits, particularly for managing diabetes. Such peptides offer an innovative and sustainable approach to complementing conventional treatments to improve patient outcomes and metabolic health. However, consumer acceptance of microalgae products requires clear regulations, ensuring sustainability, improving sensory profiles, and increasing awareness. Advances in biotechnological tools, such as optimized bioreactors and novel microbial strains, are essential to reducing production costs and enhancing product scalability. Before integrating microalgae into mainstream dietary patterns, technological research, and innovation must address safety, taste, and production costs. Exploring the potential and challenges of fermentation in creating foods: a spotlight on microalgae. Bürck, M., Lemes, A.C., Egea, M.B., Braga, A.R.C. Fermentation (2024). DOI: 10.3390/fermentation10120649, https://www.mdpi.com/2311-5637/10/12/649
PDUFA goal date is July 27, 2025 COPENHAGEN, Denmark, Dec. 12, 2024 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced that the U.S. Food & Drug Administration (FDA) has accepted for review its supplemental Biologics License Application (sBLA) in adult growth hormone deficiency (GHD) for TransCon hGH (lonapegsomatropin-tcgd; marketed as SKYTROFA ® for pediatric GHD). The FDA set a Prescription Drug User Fee Act (PDUFA) goal date of July 27, 2025. "This marks another step towards achieving our objective to expand SKYTROFA's label beyond pediatric GHD and expand its reach to address new groups of patients,” said Jan Mikkelsen, Ascendis Pharma's President and Chief Executive Officer. "Adult GHD is an undertreated condition associated with significant comorbidities and higher annual healthcare costs compared to the 5-10% of patients who receive treatment, indicative of the high unmet need.” The sBLA submission is based on results from foresiGHt, a Phase 3 randomized, parallel-arm, placebo-controlled (double-blind) and active-controlled (open-label) trial that compared the efficacy and safety of weekly TransCon hGH with weekly placebo and daily human growth hormone (hGH) in adults with GHD. The trial evaluated 259 adults with GHD aged 23 to 80 years old, randomized 1:1:1, titrated to receive a target fixed dose of TransCon hGH, placebo, or daily hGH based on age and oral estrogen intake with approximately equivalent hGH mg/week for TransCon hGH and daily hGH. TransCon hGH demonstrated superiority on its primary efficacy and key secondary efficacy endpoints at Week 38, with TransCon hGH-treated participants showing a statistically significant reduction from baseline in trunk fat and increase in total body lean mass at Week 38 compared to placebo. In the trial, TransCon hGH was generally safe and well tolerated, with no discontinuations related to study drug and with comparable safety and tolerability to daily hGH treatment. About Adult Growth Hormone Deficiency Growth hormone plays an essential role in the health of children and adults, promoting normal growth in children and maintenance of normal body composition and cardiometabolic health throughout adulthood. In adults, growth hormone boosts protein production, promotes fat utilization, enhances muscle mass, and helps regulate blood sugar levels. Adult GHD is a condition in which an individual's body does not produce enough growth hormone. Symptoms and morbidity can include central obesity, metabolic syndrome, decreased bone density, alterations in lipid profile and markers of cardiovascular risk, fatigue, general weakness, lack of muscle tone, and psychological symptoms such as cognitive impairment, social isolation, lack of motivation, and depression. 1 About Ascendis Pharma A/S Ascendis Pharma is applying its innovative TransCon technology platform to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients' lives. Guided by its core values of Patients, Science, and Passion, Ascendis uses its TransCon technologies to create new and potentially best-in-class therapies. Ascendis is headquartered in Copenhagen, Denmark and has additional facilities in Europe and the United States. Please visit ascendispharma.com to learn more. Forward-Looking Statements This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, included in this press release regarding Ascendis' future operations, plans and objectives of management are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to (i) the PDUFA goal date for SKYTROFA, (ii) Ascendis' objective to expand SKYTROFA's label and reach to address new groups of patients, (iii) Ascendis' ability to apply its TransCon technology platform to build a leading, fully integrated biopharma company, and (iv) Ascendis' use of its TransCon technologies to create new and potentially best-in-class therapies. Ascendis may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, expectations, and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Ascendis makes, including the following: dependence on third party manufacturers, distributors and service providers for Ascendis' products and product candidates; unforeseen safety or efficacy results in Ascendis' development programs or on-market products; unforeseen expenses related to commercialization of any approved Ascendis products; unforeseen expenses related to Ascendis' development programs; unforeseen selling, general and administrative expenses, other research and development expenses and Ascendis' business generally; delays in the development of its programs related to manufacturing, regulatory requirements, speed of patient recruitment or other unforeseen delays; Ascendis' ability to obtain additional funding, if needed, to support its business activities; the impact of international economic, political, legal, compliance, social and business factors. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Ascendis' business in general, see Ascendis' prospectus supplement filed on September 20, 2024 and Ascendis' current and future reports filed with, or submitted to, the U.S. Securities and Exchange Commission (SEC), including its Annual Report on Form 20-F filed with the SEC on February 7, 2024. Forward-looking statements do not reflect the potential impact of any future licensing, collaborations, acquisitions, mergers, dispositions, joint ventures, or investments that Ascendis may enter into or make. Ascendis does not assume any obligation to update any forward-looking statements, except as required by law. Ascendis, Ascendis Pharma, the Ascendis Pharma logo, the company logo, TransCon, and SKYTROFA ® , are trademarks owned by the Ascendis Pharma group. © December 2024 Ascendis Pharma A/S.JACKPOT — Jackpot Combined School officials announced the school has received two grants totaling $61,565 from the state of Nevada Office of Science, Innovation and Technology. The school, which received a Developing STEM School rating earlier this year from the Governor’s Office of Science and Technology, was awarded the grants to raise the its rating, according to an announcement on Wednesday. The rating can be raised to an Established or Model STEM School by integrating STEM into lessons, the school culture and the community. STEM stands for science, technology, engineering and mathematics. “This funding allows us to create unique opportunities for our students to learn STEM concepts through hands-on, real-world applications,” Principal Stormi McCarthy said. Jackpot Combined School staff celebrate their designation as a Developing STEM school during a ceremony in March. The first grant, a $25,000 award, will fund the Skill Struck STEM learning platform and teacher professional development, according to an announcement from the Elko County School District. The learning platform includes the launch of a student-run school store in which students will manufacture and sell products, gaining practical experiences in entrepreneurship and financial literacy, the district said. The second grant of $36,565 will support the Jackpot Community Greenhouse Project, which aims to build a commercial-grade greenhouse and provide related materials and professional development. The greenhouse will serve as a year-round outdoor classroom where students will cultivate plants, conduct research and collaborate with local industry partners, the district said. Students will gain skills in landscape design, plant science and problem-solving while addressing real-world challenges. Both initiatives align with the school’s strategic goals of improving STEM education, fostering community partnerships and preparing students for careers, according to the district. Get our local education coverage delivered directly to your inbox.
MicroStrategy , the preferred high beta play on the price of bitcoin, will join the Nasdaq 100 index, a move that could further increase demand for the controversial stock that has been on a torrid run this year alongside the price of the cryptocurrency. > Philadelphia news 24/7: Watch NBC10 free wherever you are The Nasdaq 100 comprises 100 of the largest nonfinancial companies in the tech-focused Nasdaq Composite index . A stock's addition means that ETFs – including the highly popular Invesco QQQ Trust , which has $325 billion in assets – will become automatic buyers as well. Shares of the bitcoin proxy could be set to gain off the move. They're up more than sixfold this year, compared with bitcoin's nearly 140% gain in the same period. The change, which will become effective before the market open on Dec. 23, was announced Friday after the stock market close. MicroStrategy was widely telegraphed as a potential contender for membership by investors who were looking forward to the index's rebalancing this week. "This would lead to inclusion of MSTR in some of the largest ETFs such as QQQ (5th largest ETF) etc, leading to one-time fresh buying ... and ongoing participation in future inflows," said Gautam Chhugani, an analyst at Bernstein, in a note this week ahead of the reshuffle. Additionally, "the market will likely set its sight on S&P 500 inclusion for 2025," Chhugani said. "Currently, due to profitability of its software business, it may be challenging to be considered for S&P 500 inclusion." The Nasdaq changes the constitution of the Nasdaq 100 index annually. The companies selected for inclusion are based largely on market cap rankings on the last trading day of November, which was Nov. 29 this year. Stocks must also meet eligibility requirements around liquidity and the free float percentage of their shares. MicroStrategy originally sold enterprise software, but the firm has increasingly become a bitcoin holding company. It first added bitcoin to its balance sheet in 2020, with Michael Saylor as CEO at the time, and has been leaning into that strategy in the years since. MicroStrategy now issues convertible notes to leverage its purchases, and its stock's daily trading sometimes looks like a more volatile version of bitcoin. The company now has a market cap of roughly $90 billion despite having less than $500 million in revenue over its previous four quarters, according to FactSet. Saylor told CNBC's " Squawk Box " earlier this month that he sees the company's role as " securitizing bitcoin ." "Primarily, our job is to bridge the traditional capital markets that want bonds, or they want fixed income, or they want equity, or they want options, and we plug that into the crypto economy. And we use bitcoin as the vehicle to do that," said Saylor, who is now the company's executive chairman. MicroStrategy began cranking up its purchases after the U.S. presidential election. The victory of pro-crypto President-elect Donald Trump — specifically his promise to establish a national strategic bitcoin stockpile — has propelled bitcoin to new all-time highs, achieved in part by the company's purchases. MicroStrategy now owns 423,650 bitcoins. It bought 149,880 of them in four different purchases over the past month, beginning Nov. 11. As part of MicroStrategy's hot streak this year, activists have been pushing bitcoin investing as an agenda item in shareholder meetings at companies like Microsoft and Amazon. Mining stocks like Mara Holdings have also begun employing Saylor's bitcoin yield strategy . Palantir Technologies and Axon Enterprise will also be joining the Nasdaq 100 later this month. Illumina , Moderna and Super Micro Computer will be removed from the index. Last year, the Nasdaq 100 added six companies in its annual reconstitution, including DoorDash. Five of those six stocks rose the Monday after the announcement, with an average move of 1.21%. —With reporting by Jesse Pound.
AleAnna, Inc. Announces Completion of Business Combination between Swiftmerge Acquisition Corp. ...
Thomas takes 1-shot lead over Scheffler in the BahamasIn-form sides NEC and FC Utrecht will be looking to keep their momentum going when they face off against each other at the Goffertstadion on Sunday afternoon. Both teams head into this one seeking a fourth straight victory across all competitions off the back of respective wins in their final outings before the two-week hiatus for international duty. © Imago Fresh from picking up their largest win of the season against Groningen six days earlier, NEC headed to the Mandemakers Stadion on October 9 to lock horns with RKC Waalwijk aiming to win consecutive league games for the first time since August when they beat PEC Zwolle and Fortuna Sittard. An even first-half saw Rogier Meijer 's men head into the interval on level terms, but the dismissal of Daouda Weidmann just before the break would tip the balance in the second period as Koki Ogawa , Sami Ouaissa and Ivan Marquez all netted to decide the contest. Since winning just one of their six games between September 14 and October 25, the Eniesee have won three on the spin across league and cup duty to move up to eighth in the Eredivisie table and secure safe passage into the next round of the KNVB Beker. More impressively, NEC have been impressive at both ends of the pitch in that time, having scored a whopping 13 goals, while letting in only three—all of which came in their seven-goal thriller against Zwolle which ended in a 4-3 triumph. Ahead of a tough assignment against Ajax one week later, Sunday's hosts now target yet another victory to keep the juggernaut rolling in their push to secure continental football having come within touching distance last time out. © Imago Like NEC, Utrecht were also in contention for a place in the Conference League playoffs during the 2023-24 season but eventually lost out to Go Ahead Eagles in the final of the qualifiers following a 2-1 defeat. However, missing out on European football has turned out to be a blessing in disguise for Ron Jans 's men, who have flown out of the blocks to emerge as PSV Eindhoven's current biggest threat in the title race. De Domstedelingen battled hard to claim a narrow 1-0 win over Heracles in their most recent outing on November 8 and sit five points shy of PSV at the top of the standings with a game in hand on the league leaders. Utrecht are set to have their title credentials extensively tested in the first week of December when they face off against PSV and Ajax three days apart, so a win this weekend would set them up perfectly for those heavyweight meetings. Sunday's visitors will be confident of coming away with all three points given their recent record against the hosts having lost just one of the most recent nine meetings between the teams since 2016, picking up five wins in that time. © Imago Philippe Sandler will not be playing any part for NEC in Sunday's game as he continues his battle with a muscle problem, while fellow Dutchman Dirk Proper misses out with a shoulder problem. However, Bram Nuytinck is back in contention for the home side once again having missed the victory over RKC Waalwijk last time out through a brief illness. Utrecht's Kevin Gadellaa is still unavailable for selection due to a knee problem he picked up against Roda earlier this year, and the goalkeeper is still a considerable way off returning to action. Alonzo Engwanda is also unfit to feature for the away side as Can Bozdogan prepares to miss a second straight game after coming off injured against Sparta Rotterdam earlier this month. NEC possible starting lineup: Roefs; Verdonk, Sandler, Marquez, Pereira; Sano, Hoedemakers, Hansen, Gonzalez; Ogawa, Van Crooy FC Utrecht possible starting lineup: Barkas; Horemans, Van der Hoorn, Viergever, El Karouani; Fraulo, Aaronson; Rodriguez, Jensen, Cathline; Descotte Given the confidence levels of both teams heading into this one, we are anticipating a highly entertaining affair decorated by goals. That said, we are also backing a share of the spoils with honours even at the end of the 90 minutes. For data analysis of the most likely results, scorelines and more for this match please click here .
Here's How Much You Would Have Made Owning Thermo Fisher Scientific Stock In The Last 10 YearsFrom Pride employee resource groups to a recurring wave of rainbow logos each June, LGBTQ+-friendly workplaces can feel more like the rule than the exception in 2024. Yet, while corporate leaders pat themselves on the back, many queer employees across Canada are still quietly navigating challenging workplace dynamics tied to their sexual orientations and gender identities. For these employees, true equity and inclusivity goes beyond gender-neutral bathrooms and company-sponsored Pride events. It means addressing deeper, often overlooked issues that remain largely invisible to those outside the LGBTQ+ community. It’s an issue that Nate Shalev, an inclusivity speaker and adviser based in Brooklyn, N.Y., feels strongly about. They posted about some of those barriers in a LinkedIn post, where they are ranked as one of the U.S. and Canada’s Top LGBTQIA+ Voices. “When I was told I would have to travel for work, my immediate reaction would be panic,” they wrote. “I was concerned about booking travel with my legal name and risking my team calling me by a name I no longer use, getting through TSA as a trans person with my dignity intact ... [and] navigating queer and transphobia at hotels or in taxis, or anywhere, in front of my co-workers.” Through their consultancy, Revel Impact, Shalev draws on past experiences with “really bad bosses” to help build more inclusive workplaces, educating companies on the barriers their LGBTQ+ team members may be facing – on top of simply getting their jobs done. Barriers like: “Is the conference you asked me to go to safe? What about that client meeting? The whole team is going for a happy hour, but this bar isn’t LGBTQ-friendly. Should I leave? Would that make me look like I wasn’t a part of the team?” Shalev says these sorts of concerns are routinely dismissed or there’s no clear channel through which to handle them since they don’t rise to a legal level of discrimination, despite having negative affects. While most organizations in North America have anti-discrimination policies in place, Ottawa-based talent and brand specialist Lindsay Moorcroft says that doesn’t necessarily mean those policies are sufficient. “Unless you’re building your programs and policies with the [affected] people in the room, there’s always the possibility for something to be forgotten,” Moorcroft says, reflecting on a previous job at a small startup where she was the only out queer employee. “Pronouns weren’t being asked in meetings. They weren’t shared in e-mail signatures. There was no option to even talk about that. So then it’s like, do I want to be the person who brings it up?” she says. For Kaitlin Geiger-Bardswich, a communications and advocacy director in Ottawa, the risk of speaking up paid off. Although she works for a national non-profit she calls “progressive” and “feminist,” bereavement leave didn’t include pregnancy loss until she advocated for it after experiencing a miscarriage herself. “Even if it’s not a miscarriage, when a fertility treatment doesn’t work, when an embryo transfer doesn’t work, there is that grief,” she says. Fertility issues aren’t specific to the LGBTQ+ community, but “gay couples, by definition, typically need to access fertility treatment of some kind,” as Geiger-Bardswich says. “So it’s more likely that if you have gay employees who are interested in parenting, they’re going to have to navigate this.” According to Fertility Matters Canada , more than half of Canadian employers don’t provide fertility benefits, including drugs and treatment costs. And only seven provinces provide public funding to cover partial costs of fertility treatment. In Geiger-Bardswich’s case, she and her wife relied on limited OHIP coverage when trying to conceive, while paying thousands of dollars out-of-pocket for medication and donor sperm. She says she was grateful to have flexibility in her work hours, which made it easier to attend doctor’s appointments throughout the in-vitro fertilization process without fear of repercussions. Flexible work arrangements, including remote work, can also benefit transgender employees who are transitioning or who are repeatedly misgendered at the office, says Shalev. Geiger-Bardswich notes that as anti-trans and anti-LGBTQ+ rhetoric increases around the world, it adds another layer of concern for queer Canadians. She points to Italy’s push to remove non-biological parents from birth certificates as an example. “I hope that’s not going to happen in Canada,” she says. “But with how things are happening around the world, there is nervousness around the legal benefits and legal situations for parents like us.” So, what can workplaces do to achieve real, meaningful inclusivity? Shalev says it’s about taking a pro-active, rather than reactive, approach. This could look like ensuring there’s space for preferred names on all applications, forms and other communications. Before international trips, a systematic pretravel questionnaire might allow queer employees to request extra security, a travel companion, a NEXUS membership or a car service to make the experience safer and smoother, Shalev says. “It doesn’t have to feel complicated. Actively create spaces for these conversations to happen. Ask folks what they need,” says Shalev, noting that this has been more difficult in recent years with LGBTQ+ issues growing increasingly politicized. “Because queer issues have been politicized so much, there’s this sense that it’s a taboo topic. That’s a big shift I’ve seen, versus it just being inclusion work and wanting to support colleagues. Trans folks aren’t politics. We’re people.” One organization that appears to be embracing a pro-active approach is Moorcroft’s current employer, ecobee, a home automation company headquartered in Toronto. The company’s diversity, equity and inclusion (DEI) offerings include an LGBTQ+ allyship group, a private social channel for LGBTQ+ employees and a policy-focused working group. Most importantly, Moorcroft says, a variety of voices are in these rooms alongside her, including those of senior leadership. “DEI means nothing if the top of the company is not supporting it, and it’s not in their [budget],” she says. Every organization has different needs and resources, which is why Shalev says, “It’s not one-size-fits-all.” Pride at Work Canada and Great Place to Work provide toolkits for organizations looking to improve inclusion, with strategies ranging from collecting data on employee demographics to administering queer mentorship programs. While certain measures may seem niche, “LGBTQ+ inclusion benefits us all,” Shalev says. “When I do workshops, of course I know there are other queer folks in the room. But then there are the parents of trans kids, or somebody with a partner who’s trans. Our workplaces are microcosms of our larger society, and if we create better workplaces, we can also create better communities and [and better] worlds.” Interested in more perspectives about women in the workplace? Find all stories on The Globe Women’s Collective hub here , and subscribe to the new Women and Work newsletter here . Have feedback? E-mail us at [email protected] .