dwight howard spin ph

Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access. It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.Jim Harbaugh and Chargers focused on accomplishing more after wrapping up playoff berthdwight howard spin ph 。

EAGAN, Minn. (AP) — Minnesota Vikings linebacker Ivan Pace Jr. has been placed on injured reserve after hurting his hamstring Sunday in a 30-27 overtime victory over the Chicago Bears. The move announced Tuesday means that Pace must miss at least the Vikings next four games. The Vikings also activated outside linebacker Gabriel Murphy from injured reserve and signed linebacker Jamin Davis off the Green Bay Packers practice squad. Pace, 23, had started each of the Vikings nine games this season. The 2023 undrafted free agent from Cincinnati had 56 tackles — including six for loss — and three sacks. Murphy, 24, signed with the Vikings as an undrafted free agent this spring. He was placed on injured reserve Aug. 27. Davis had joined the Packers practice squad Oct. 29 after getting released by the Washington Commanders a week earlier. Washington selected him out of Kentucky with the 19th overall pick in the 2021 draft. The 25-year-old Davis has 282 tackles, seven sacks, one interception, two forced fumble recoveries and two forced fumbles in his NFL career. He led the Commanders with a career-high 104 tackles in 2022. The Vikings (9-2) host the Arizona Cardinals (6-5) on Sunday. AP NFL: https://apnews.com/hub/NFL

Otherworldly plans for vast HOLLOW skyscraper in the desert unveiled in latest part of £1tn NEOM Saudi vanity projectOil and gas expert, Tonye Cole, has expressed optimism that fuel prices would likely reduce with the repair of national refineries in Nigeria Cole, however, explained that fuel may not drop to the N700/litre mark due to some issues that the country has to deal with Legit.ng reports that currently, the price of fuel in Nigeria is above N1,000, much to the displeasure of many citizens PAY ATTENTION: Got a Minute? Complete Our Quick Survey About Legit.ng Today! Legit.ng journalist Ridwan Adeola Yusuf has a decade of business journalism experience with in-depth knowledge of the Nigerian economy , stocks, and general market trends. Port Harcourt, Rivers state - Tonye Cole has said "there has to be a concise and dedicated policy of ensuring that there is the manufacturing of critical fuel components so that Nigeria does not need to import those pieces of machinery". Cole, the governorship candidate of the All Progressives Congress (APC) in Rivers state in the 2023 general elections, spoke on Channels Television 's 'Politics Today' programme on Tuesday evening, November 26. The programme was monitored by Legit.ng . Read also NNPC reacts as trucks begin loading petrol after PH refinery begins production Cole reacts to Port Harcourt refinery revival The erstwhile Rivers gubernatorial candidate spoke against the backdrop of the trending update that the Nigerian National Petroleum Company (NNPC) Limited fulfilled its pledge of re-streaming the Port Harcourt Refining Company (PHRC), signalling the commencement of crude oil processing from the plant and delivery of petroleum products into the market. PAY ATTENTION: Follow us on Instagram - get the most important news directly in your favourite app! Ask about the possibility of Nigerians buying fuel for N700 per litre considering the NNPCL 's efforts, the one-time group executive director of energy conglomerate Sahara Group, explained: "There are certain things that you have to deal with. First of all, there are many components that you are still bringing in. All the things that were refurbished in the refinery were refurbished by machining brought into the country. So we still have a huge foreign exchange component that we have to deal with." Cole added: "There has to be machining of tools and replacement parts here in Nigeria for refineries that are here, for you to begin to see all of those gains. As long as we are still importing turbines, importing bolts, knots, screws, and all of that, we have an issue." Read also After Port Harcourt refinery, Shehu Sani mentions 1 fuel processing facility Nigerians look forward to Watch the video below: Sani reacts Port Harcourt refinery begins operation Earlier, Legit.ng reported that former Kaduna senator, Shehu Sani, shared his reaction after the Port Harcourt refinery commenced crude oil processing. Shehu Sani in a post shared on his X page on Tuesday, November 26, hailed the NNPCL led by Mele Kyari. He stated that the refinery's operations should lead to a reduction in petroleum prices and improve the lives of Nigerians. PAY ATTENTION : Legit.ng Needs Your Opinion! That's your chance to change your favourite news media. Fill in a short questionnaire Source: Legit.ng

In a strategic move paralleling real-world tensions, board game maker Mizo Games is set to unveil '2045', a game simulating Taiwan's defense against a hypothetical Chinese invasion. Scheduled for a January 2025 release, this immersive experience invites players to navigate the complexities of military strategy amid growing geopolitical unrest. The game's narrative unfolds against the backdrop of escalating Chinese military maneuvers near Taiwan, incorporating a mix of action cards and role-playing elements. Participants assume various roles, including Taiwanese soldiers and Chinese sleeper agents, to experience the prelude to a fictional invasion, a scenario that has garnered significant crowdfunding support. This initiative arrives as Taiwan ramps up its own defensive measures, recently conducting its inaugural 'tabletop' exercise simulating military engagement with China. As the game prepares for a global launch, it has already sparked discussions on military strategy and the implications of potential conflict in the region. (With inputs from agencies.)BEMIDJI — The Bemidji Area Full Gospel Businessmen’s Fellowship of America chapter is set to meet at 8 a.m. on Saturday, Dec. 7, in the Beltrami Electric Conference Room, 4111 Technology Drive NW. A light breakfast will be served and all are welcome to attend. The keynote speaker will be Ryan O'Leary. His testimony will focus on his ministry work with Indigenous groups in North America. O'Leary is a member of the Bois Forte Band of Ojibwe in northern Minnesota. He grew up playing hockey and eventually played at the University of Denver and was drafted to play professionally by the Calgary Flames in the fourth round back in his draft year, a release said. Along with his hockey background, O'Leary has an extensive ministry background and has served as a lead pastor for two congregations for a total of 13 years. He currently works for a global missions organization and leads two ministries based out of Bemidji. O'Leary leads a ministry called the First Peoples Initiative, which involves developing a ministry to all of the First Peoples groups in North America. According to the release, there are around 9.5 million tribal members in the U.S. and about another 2 million First Nations people in Canada. He also serves as president of the National Association of Native Evangelicals and serves on the National Association of Evangelicals board of directors based in Washington D.C. O'Leary and his family reside in Bemidji. He has been married to his wife Kristen for over 21 years and has four children.

The rise of dating apps, social media, and the prominence of technology in everyday life has transformed the dating landscape as we know it. With a world of information readily accessible at our fingertips—whether it's TikTokers sharing shocking first-date horror stories, viral threads dissecting awkward encounters, or podcasts breaking down relationship dynamics—one might assume that identifying "green" and "red flags" on a first date would be straightforward. But dating remains subjective, and opinions on what constitutes a "flag" can vary widely. While some express that modern dating places too much pressure on individuals by setting excessively high standards, others view it as an opportunity to be more selective—treating dating as a process of elimination, akin to a job interview, where only the best matches pass to the next stage. To navigate this evolving dating culture, we reached out to relationship experts to uncover what they consider the ultimate green flag on a first date. Their insights shed light on the subtle yet significant signs that reflect compatibility and mutual respect—factors that are more important than ever in today's fast-paced, high-pressure dating world. Lisa Marie Bobby, PhD, LMFT, LP, BCC, Founder & CEO, Growing Self Counseling & Coaching One of the most promising signs on a first date is sincerity combined with "boundaried openness." This means someone who is open and authentic, but also respectful of the context—like sharing just enough about themselves to build a connection, without oversharing or coming on too strong. Pay attention to how they talk about their relationships, too. People who have a history of healthy relationships tend to have positive things to say about their friends and family. They'll also likely demonstrate conscientiousness—showing up on time, being considerate, and showing genuine interest in getting to know you. And here's a surprising one: a green flag is not feeling crazy, overwhelming chemistry. While it's fun to feel sparks flying, those intense emotions can sometimes cloud judgment. Healthy, emotionally available people tend to feel more calming than chaotic. Instead of intense fireworks, you'll feel a sense of interest, curiosity, and ease—and that's a really good thing. Duana Welch, PhD, Author and Dating Coach If your date shows kindness and respect and honesty without oversharing about someone who hurt them, that's huge! Ask them, "If your ex were here right now, what would they say was behind the breakup?" "I thought we were exclusive, but they were still seeing other people" is a green flag, whereas "I don't know what they would say, but they were a total [insert insult]," or giving all the details to someone they barely know (you!), is deep red. My clients have found this to be a powerful early question, not only because it reveals character, self-control, and emotional intelligence, but it also detects potential danger: the worst way a person speaks about someone else is how they will eventually treat you. Ask them this question, and you'll give them room to show you who they are! Lorne Campbell, PhD, Professor, Psychology, Western University A demonstration of kindness is the biggest green flag on a first date. For example, if in a restaurant, how does the person interact with and treat the wait staff? Kindness is a core feature of interpersonal traits that most people tend to prefer in committed relationships. Denise Marigold, Associate Professor of Social Development Studies at Renison University College, University of Waterloo Paying attention to how the other person makes you feel is important. Do they make you feel comfortable and safe? Of course, a little bit of discomfort is okay to the extent that it reflects the awkwardness or anxiety that can come with a first date. But discomfort that feels threatening in some way—for example, your date exhibiting some controlling behaviours—should be taken more seriously. When two people are getting to know each other and develop a connection, reciprocal self-disclosure is important. You share a little bit, the other person shares a little bit, you share a bit more, they share a bit more, and so on. Ideally this would be pretty balanced, displaying mutual interest and respecting each other's boundaries. Also consider how the other person responds when you share something. Are they listening to understand you, or to decide what they will say next? Do they let you finish, or do they interrupt you with their own perspective? If they do the latter, it's a green flag. Ellyn Bader, PhD, C o-Founder & Director,The Couples Institute, Menlo Park, California The purpose of a first date is to see if you want to have a second date, that's all. So the biggest green flag on a first date is enjoying their company enough that you want to continue the connection. This could look like enjoying the way you feel, how you are when you're with them, enjoying what they bring out of you, feeling relaxed and at ease, etc. Another indicator of a green flag would be the following: shared interests, shared history, shared friendships, shared commitments to same causes.