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2025-01-12
The last fight for Jake Paul was a global phenomenon. An estimated 108-million live viewers in around 65 million households worldwide tuned in to Netflix last month to see the influencer-turned-boxer defeat legendary fighter Mike Tyson in a unanimous decision, making it the most-streamed sporting event. Paul, 27, and Tyson, 58, reportedly made tens of millions of dollars from the event in Texas. It’s only a slight exaggeration to say that everybody wants to be the next person to face Paul (11-1, 7 KOs). “It’s boxers, it’s athletes, it’s celebrities — pretty much everyone in the world wants to challenge Jake Paul at this point in time, which is pretty remarkable just four years into his career and 12 fights as a professional,” said Nakisa Bidarian, who co-founded and runs Most Valuable Promotions with Paul. So who will it be? And which platform will get to air the next fight that may attract millions of more eyeballs? Bidarian couldn’t say — not because it’s a closely guarded secret, but because those decisions have yet to be made. “We’re definitely still looking at what the options are,” Bidarian said. “It starts with getting to an alignment with MVP, Jake and the rest of the company on where we’re going to put our product going forward. We obviously have been very successful with DAZN , we’ve been very successful with Netflix , we’ve been successful on pretty much every platform that we’ve been on. “And now we’re at a point in time where we want to have a long-term media rights partner. Part of that would include Jake Paul, part of that would include Amanda Serrano and the rest of the MVP roster that we’re building. And then once we have that, we can then determine what’s the next appropriate step for Jake based on his career path, ambitions and aspirations.” Bidarian offered some insight into those decisions, a time frame for when Paul’s next fight will take place, the massive success of the Tyson fight and more during a phone interview Thursday. (The questions and answers have been edited for length and clarity) What is the thought process in determining Paul’s next opponent? It’s a very unique set of circumstances. We’re at a point in the sport of boxing where there is definitely a transition from the old guard to the new guard. Whether it’s Tyson Fury and [Oleksandr] Usyk , who are fighting in a couple of weeks, whether it’s Anthony Joshua or whether it’s Canelo [Álvarez] — any big name in the sport you can think of, they’re all getting to a point where their prime may be fading. When you look at the next generation, there’s really three names in the U.S. from my perspective. One, by a longshot, being Jake, that no one comes close to. And then there’s two other guys who’ve called out Jake — [Gervonta] “Tank” Davis and Ryan Garcia . Jake’s never been in a more fortunate position in terms of demand, and when I say demand I mean in terms of distribution partners that want to work with him and MVP and also in terms of fighters that want to share the ring with him because they understand the kind of box office and attention that he drives. Jake has two paths that he’s focused on. The most important path to him is to become a world champion. ... He’s going to continue on the path to grow as a boxer, increasing the level of competition to then get to the point where he can challenge for a championship. And then he’s also going to look to do these disruptive, big events which ... are still gonna be very competitive. Very, very competitive. Is there any particular opponent that might pique his interest over the other possibilities? I think we’re just evaluating. Part of when you have so much success is, you know, the biggest names are calling him out, but everyone has an expectation that is I’m gonna make tens of millions of dollars to fight Jake Paul . And we pay people very well and we want to be in a business that is profitable for all parties, but we’re not gonna do things that don’t make economic sense. So part of the process is understanding what opponents are realistic. Is there a timetable in mind for Jake’s next fight? We’re holding dates in different cities starting in mid-April all the way through mid-July, so giving ourselves the flexibility to have him return anywhere from April to July. Were you expecting the Tyson fight to generate as much interest as it did? I think what surprised us was how the entire world was interacting with this event. Seventy-eight countries on Netflix, it’s the No. 1 piece of content. There’s no piece of content like that that exists. It just doesn’t happen. ‘Cause even the World Cup final , there’s two countries that are highly engaged and there’s a lot of countries that don’t care. The Olympics on any given day there’s different competitions and different teams and different rounds that pique and don’t pique interest. So we had something that — you know, Super Bowl , unbelievable viewership, but highly concentrated. It was the first time — I heard this from multiple journalists — where journalists’ mothers, women who were in their 50s, 60s, 70s, were talking to the journalists’ children about a fight. That just doesn’t happen. So that was a very special combination when you connected to different audiences of these two guys and what it meant. Did any of this even seem possible just a few years ago? When we started MVP in August of 2021, we certainly had a vision of doing big, disruptive things. And if you look at Jake’s events, no matter how you slice ‘em, if you look at pure global interest, pure social media, they’re the biggest events outside of the Super Bowl . The amount of people who want to view and see what he’s up to is pretty phenomenal. And we do that with the right match making and bringing different audiences together. But did we think that we could within three years partner with the biggest media platform in the world and effectively break the internet? No.Max George ‘staying positive’ amid hospital stay due to heart issuesRevolutionary prostate cancer test set to save thousands of liveswild casino payout reviews

After more than 7 years of treatment for Parkinson's syndrome, trembling and stiffness are significantly reduced after robotic surgery 12-13-2024 10:58 PM CET | Health & Medicine Press release from: ABNewswire When it comes to Parkinson disease, many people think of Parkinson syndrome. In life, many people who do not have professional medical knowledge cannot clearly distinguish between these two diseases, and even confuse or completely equate them in many cases. .So what kind of disease is Parkinsonism and what are the specific effects it has on people?Today we will learn about it through a case. Image: https://ecdn6.globalso.com/upload/p/857/image_other/2024-10/h1-1.png Aunt Li is 68 years old this year. Seven years ago, there was no obvious cause for involuntary shaking of the lower left limb, which was a static tremor. She visited a hospital without a clear diagnosis and the drug treatment was ineffective.After half a year, it developed to the upper left limb and there was also a static tremor, slow movement, a slight stiffness of the limbs, and a loss of smell.Aunt Li, who has sought medical treatment for many times, developed involuntary shaking and stiffness of her limbs two years ago, and her movement was slow (difficult to start and slow to turn around). The symptoms were mainly on the left side. For further treatment, he came to our hospital.After a joint diagnosis by several experts in our hospital, it was found that Aunt Li is not a simple Parkinsonism, but belongs to Parkinsonism syndrome. There is an essential difference between the two.Parkinsonism also includes other diseases caused by other reasons that are similar to the symptoms of Parkinsonism.After fully communicating with Aunt Li herself and her family, it was decided that Professor Tian Zengmin would perform robotic stereotactic surgery for her to solve the problem of shaking and slow movement of the left limb.The difference between Parkinsonism and Parkinsonism1 Different age of onsetParkinsonism can occur in any age group, and the youngest patient with Parkinsonism that our hospital has ever treated is only 26 years old.Parkinson's disease usually develops in middle-aged and elderly people. In recent years, with the increase of social pressure, it has also shown a trend of youth.2 Different clinical manifestationsClinically, in addition to the same manifestations as Parkinson's disease such as slow movement, sluggish expression, increased muscle tone, tremor, etc., Parkinson's syndrome often has the same manifestations left over from the original onset. The 26-year-old juvenile patient with Parkinson's syndrome mentioned earlier is also accompanied by hereditary spastic paraplegia.The imaging manifestations of Parkinson's disease are not characteristic, while Parkinson's syndrome often has corresponding changes or characteristic changes.3The etiology and pathogenesis are different.The pathological changes of Parkinson's disease are mainly due to the degeneration of dopamine neurons in the melanoplasm of the midbrain, so that they cannot produce enough dopamine and become ill.On the other hand, Parkinson's syndrome is a syndrome of known etiology. The pathological changes in the brain are caused by lesions of the brain, the melanoplasm and striatum pathways of the midbrain, and degeneration of dopamine neurons, resulting in insufficient production of dopamine or inability to transmit dopamine to maintain normal nerve function. Caused.4 Different treatments.The treatment of Parkinsonism is not the same as the treatment of Parkinsonism. Early drug treatment has a better effect on Parkinsonism, but the effect on Parkinsonism is poor.Technical introduction. Robotic stereotactic surgery.In 2019, Nuolai International Medical Center introduced robot-assisted frameless brain stereotactic surgery. With the help of medical image scanning, three-dimensional visualization, multi-modal image fusion and other technologies, the brain lesion area can be accurately found.After planning the puncture path to accurately reach the surgical target, and solving the lesion problem through thermal coagulation, biological therapy, etc., brain diseases can be fundamentally treated, and the effect is very mature and successful.Technical advantage.Compared with the trauma caused by traditional craniotomy, frameless brain stereotactic surgery has the advantages of scientific and technological innovation in four aspects: minimally invasive, accurate, efficient and safe.The entire operation takes only 30 minutes, the wound is only 2-3 mm, and the positioning accuracy reaches 1 mm. After 2-3 days of postoperative observation, you can be discharged from the hospital.The risk rate of surgery such as infection and bleeding is much lower than 1%, and it has obvious effects on nearly 100 kinds of extranasal diseases such as cerebral palsy, epilepsy, cerebral hemorrhage, and Parkinsonism. Image: https://ecdn6.globalso.com/upload/p/857/image_other/2024-10/h2.pngImage: https://ecdn6.globalso.com/upload/p/857/image_other/2024-10/h3.pngImage: https://ecdn6.globalso.com/upload/p/857/image_other/2024-10/h4.png After the operation, combined with a series of symptomatic treatments such as drugs and rehabilitation, Aunt Li's upper left limb trembling, stiffness and other symptoms were significantly reduced, and walking was more flexible than before. The patient and his family were very satisfied with the treatment effect. Media Contact Company Name: Nuolai Biomedical Technology Co., Ltd. Email:Send Email [ https://www.abnewswire.com/email_contact_us.php?pr=after-more-than-7-years-of-treatment-for-parkinsons-syndrome-trembling-and-stiffness-are-significantly-reduced-after-robotic-surgery ] Phone: +86 18500761086 Address:Tai'an, China: No. 282, Tianzhufeng Road, Taishan District, Taian City, Shandong Province Beijing Branch Office: Chang'an Taihe, Dongcheng District City: Beijing Country: China Website: https://www.bjnuolai.com/ This release was published on openPR.Max George ‘staying positive’ amid hospital stay due to heart issues

RALEIGH — North Carolina Gov. Roy Cooper is leaving his job after eight years in which the southern Democrat picked his moments against a Republican-dominated legislature, winning big on Medicaid expansion and clean energy while falling short in fights over private-school vouchers and abortion rights. Cooper, who steered the state through the coronavirus pandemic, Hurricanes Helene and Florence and an early flashpoint in the culture wars over access to public restrooms, was barred from seeking a third consecutive term. He is wrapping up 24 consecutive years in statewide office — the first 16 as attorney general. In a December interview with The Associated Press at the executive mansion, Cooper reflected on his gubernatorial terms with an emphasis on the positive — an easier undertaking compared with many Democrats around the country in the aftermath of this year's election. "To be able to wake up every morning and get to lead the state that you love has been humbling, challenging and fulfilling. I have really valued every day," said Cooper, who will be succeeded by state Attorney General Josh Stein, a fellow Democrat, in early January. Faced with veto-proof majorities for almost half of his time as governor, Cooper was unable to stop many GOP initiatives, including deep income tax cuts, taxpayer-funded vouchers to help public school students attend private schools and new restrictions on abortion. But Cooper, one of several Democratic governors seen as potential contenders for federal office, managed last year to persuade GOP legislative leaders to expand Medicaid under the Affordable Care Act — something he had sought since getting sworn in as governor in 2017. Now 600,000 low-income adults are enrolled in the program a year ahead of expectations. "This is a generational investment in people's health," Cooper said during a farewell address last week in Nash County, where he grew up and launched his first gubernatorial campaign in 2015. Another bipartisan agreement was reached in 2021 on a milestone energy bill that ordered sharp reductions in greenhouse gas emissions from power plants. Cooper takes credit for conditions that led to big corporate expansions that he says have contributed to hundreds of thousands of new jobs being created during the past eight years, including those in the clean energy sector. But he also gives his rare praise to Republican lawmakers for all working together on offering economic incentives that have lured companies such as Apple, Toyota and Boom Supersonic to build in the state. Still, Republicans contend Cooper receives too much acclaim for the state's broad economic success and has pushed for reckless state spending at every turn. Half of his record 100-plus vetoes were overridden. "There has not been a governor who has had less of his agenda enacted and North Carolina has succeeded in spite of his leadership failures," state GOP spokesperson Matt Mercer said. Regardless, Cooper's perceived accomplishments in a swing state raised his national profile during this year's presidential campaign, making him as a potential running mate for Kamala Harris until he said it "just wasn't the right time" for him and for North Carolina. Now Cooper, 67, will have to decide whether trying to unseat U.S. Sen. Thom Tillis, a Republican, in 2026 is in the cards after holding what he calls the "best job I have ever had." While North Carolina Democrats have won eight of past nine gubernatorial elections, they haven't won a U.S. Senate race since 2008. "If you're going to run for public office again, you must have your heart and soul in it, you must have the fire in the belly," Cooper told the AP. With that in mind, he said he planned to take a couple of months to clear his head before deciding what's next: "I'm going to think about how I can best contribute to the things that I care about." It's little wonder why many North Carolina Democrats want Cooper to remain on the political stage. He has never lost a race for state office, from the legislature in the mid-1980s and including a 10,000-vote win over then-GOP Gov. Pat McCrory in 2016. "What he's done really from my perspective is he's kept the progressive flame alive in North Carolina in a difficult time," said Gary Pearce, a longtime Democratic political consultant who worked with four-term Gov. Jim Hunt. "I'm not sure anybody else could have done it as well as he did." Cooper took on Republicans even before he was sworn in. As governor-elect he began a series of lawsuits challenging legislation approved weeks before he took office that shifted executive branch powers to the legislature. The legal results were mixed, and even now litigation over his appointment powers remains in court. This month, Republican lawmakers enacted more changes that would weaken Stein's gubernatorial authority. Two lawsuits related to that law have been filed so far. In his first three months in office, Cooper worked with lawmakers to partially repeal the 2016 "bathroom bill," which had required transgender people to use public bathrooms aligned with the gender on their birth certificate. The law had lost the state business, including canceled sporting events and job expansions, and "North Carolina's reputation was in tatters," Cooper said. Eight years later, "we built a North Carolina that is healthier, better educated, with more money in people's pockets, and we stand ready to welcome prosperity with open arms for generations to come," Cooper said. Republicans cite several shortcomings in Cooper's administration. They include spending overruns at the state Department of Transportation; continued delays to rebuild or renovate homes for eastern North Carolina residents after Hurricanes Matthew in 2016 and Florence in 2018; and executive orders that helped extend restrictions on businesses and school instruction during the COVID-19 pandemic. "It's been painful dealing with the governor fiscally," Republican state Sen. Warren Daniel said. "I just think he's not very good at managing government." Cooper has defended his actions, particularly his pandemic leadership, saying North Carolina came out better than many other states. Even in policy defeats, Cooper secured the admiration of supporters. The Democratic governor used lots of political capital in 2023 trying unsuccessfully to block a law that changed the state's ban on most abortions from after 20 weeks of pregnancy to 12 weeks. Republicans overrode his veto. "There's simply no governor who's ever fought as hard or as publicly as Gov. Cooper has to protect access to abortion," said Paige Johnson with Planned Parenthood South Atlantic. Plenty of North Carolinians see that differently. Cooper's opposition to the abortion bill reflects an administration that "has been consistently hostile to policies that serve the best interests of North Carolina families," said Tami Fitzgerald, executive director of the NC Values Coalition. Cooper said he has confidence that Stein, who succeeded him as attorney general, will "continue a lot of the progress that we have made." Cooper hired Stein two decades ago, while attorney general, to be his consumer protection chief. Otherwise, Cooper knows that he'll miss "having the opportunity every single day to do something to make a real difference." "That's what you can do in this job," he added. "And whatever I decide to do, that's going to be hard to replicate."'Where are we supposed to go?': Emotional reaction to Ford government’s hard line on encampmentsThe Wanted star Max George has said he is “staying positive” while in hospital waiting for tests that could shine a light on issues with his heart. In a post to Instagram on Thursday the singer, 36, explained that he went to hospital after feeling “really unwell” and added that he needed “a lot more tests” to determine “what surgery I will need to get me back on my feet.” Updating his fans, George posted a video from his hospital bed on Friday, and said he “had a bit of a rough day”. A post shared by Max George (@maxgeorge) He added: “My heart rate dropped a bit this morning, which was, it was a little bit scary. “But everyone here is amazing, so wanted to get it back up a little bit and get it stable again, which is great. “Reason I’m not... like a lot of friends and family are asking why I’m not just going in and having anything (like surgery) done yet, because there’s so many tests that need to be done before we do anything. “So I just need to get through till, I guess, next week. Get all the tests done, and then they’ll know exactly what to do, because otherwise, obviously, they’ll be able to do something, but it’ll be better doing it with all the information that they need. “But, yeah, it’s shit, but still here and staying positive. “And thanks everyone as well for all the lovely messages and any friends and family and that that have messaged that I haven’t got back to. “I see you all and yeah, means a lot. Much love and have a nice Friday night.” George rose to fame in the 2010s with The Wanted, who had a number of hit songs including All Time Low, Glad You Came and Heart Vacancy. His bandmate Tom Parker died in 2022 at the age of 33 after being diagnosed with an inoperable brain tumour. George, who helped carry Parker’s coffin at his funeral alongside fellow bandmates Siva Kaneswaran, Jay McGuiness and Nathan Sykes, previously said on This Morning that he continued to message his late bandmate following his death as it brought him “a bit of comfort”. He also appeared in the US musical series Glee as Clint and in his band’s reality series The Wanted Life. Over the years, he has competed in a number of competition series including Strictly Come Dancing in 2020, Bear Grylls: Mission Survive and Richard Osman’s House Of Games. George’s girlfriend is former EastEnders star Maisie Smith, who appeared on BBC One dancing competition series Strictly Come Dancing in 2020 at the same time as George, though they have previously said that romantic sparks only began to fly in 2022. He was due to appear on a MasterChef Christmas special before the BBC pulled the show from its festive schedule amid allegations about the conduct of judge Gregg Wallace across a range of shows.

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A NEW test for prostate cancer shown to be more than 90 per cent accurate at detecting the disease is set to save thousands of lives. The simple blood test, developed by a British biotech company, identifies abnormal immune cells which act as a marker of this cancer. Ministers have been urged to adopt this test as the existing prostate specific antigen (PSA) blood test is notoriously unreliable. Three out of four men with a raised PSA level do not have prostate cancer and one in seven men with a normal PSA result have the disease. Six times gold-medal winning Olympic cyclist Sir Chris Hoy, 48, who was diagnosed with terminal prostate cancer earlier this year, has been campaigning for more screening of men aged 45, as opposed to the current age of 50. Trials have shown the new test, the Epi-Switch PSE, developed with scientists from the University of East Anglia and London’s Imperial College, in collaboration with Oxford Biodynamics, can pick out men with prostate cancer 92 per cent of the time. It was also able to correctly identify men who did not have prostate cancer 94 per cent of the time. The charity Prostate Cancer Research recently delivered a report to Parliament outlining the benefits of the EpiSwitch PSE test and other similar advanced prostate cancer blood tests. Its report was presented at a summit of MPs attended by Gary Lineker , the Match of the Day presenter, Oscar-winning film director Sir Steve McQueen and the Foreign Secretary David Lammy. The charity believes the new blood test could save thousands of lives a year and reduce the number of unnecessary biopsies by 50 per cent. There are more than 52,000 new cases of prostate cancer diagnosed each year and 12,000 deaths. But unlike breast, bowel and cervical cancer, there is currently no reliable NHS screening for the disease. Every year tens of thousands of men undergo a tissue biopsy of the prostate gland and an expensive MRI as a result. The EpiSwitch PSE test detects specific immune cell changes in the blood if prostate cancer is present. When combined with the PSA test the cancer check is far more accurate than PSA alone. Dr Jayne Spink, research director of the charity, said: “The future of prostate cancer screening lies in integrating new tests. “Our report finds we could save 19 thousand years of life from a five-year screening programme if the technology that already exists were to be adopted.” Prostate Cancer Research believes that the timing is ideal to explore innovative screening strategies and consider their benefits to patients, their loved ones and society as a whole. Despite the significant increase in accuracy detection rates demonstrated by the EpiSwitch PSE, Oxford BioDynamics has been unable to land a large-scale clinical study with the NHS. The PSE test is on offer privately in the UK, including at the London Clinic which diagnosed King Charles with a prostate-related condition, and a network of more than 140 Goodbody clinics across the country. A Department of Health and Social Care spokesperson said: "Prostate cancer patients are waiting too long for diagnosis and treatment, and we are working to change that. "The UK National Screening Committee is urgently reviewing the evidence for prostate cancer screening programmes including targeted approaches for those at higher risk. "Our first ever men's health strategy will consider how to prevent and tackle the biggest health problems affecting men of all ages.”

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