COPENHAGEN, Denmark, Dec. 12, 2024 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced that the U.S. Food & Drug Administration (FDA) has accepted for review its supplemental Biologics License Application (sBLA) in adult growth hormone deficiency (GHD) for TransCon hGH (lonapegsomatropin-tcgd; marketed as SKYTROFA ® for pediatric GHD). The FDA set a Prescription Drug User Fee Act (PDUFA) goal date of July 27, 2025. “This marks another step towards achieving our objective to expand SKYTROFA’s label beyond pediatric GHD and expand its reach to address new groups of patients,” said Jan Mikkelsen, Ascendis Pharma’s President and Chief Executive Officer. “Adult GHD is an undertreated condition associated with significant comorbidities and higher annual healthcare costs compared to the 5-10% of patients who receive treatment, indicative of the high unmet need.” The sBLA submission is based on results from foresiGHt, a Phase 3 randomized, parallel-arm, placebo-controlled (double-blind) and active-controlled (open-label) trial that compared the efficacy and safety of weekly TransCon hGH with weekly placebo and daily human growth hormone (hGH) in adults with GHD. The trial evaluated 259 adults with GHD aged 23 to 80 years old, randomized 1:1:1, titrated to receive a target fixed dose of TransCon hGH, placebo, or daily hGH based on age and oral estrogen intake with approximately equivalent hGH mg/week for TransCon hGH and daily hGH. TransCon hGH demonstrated superiority on its primary efficacy and key secondary efficacy endpoints at Week 38, with TransCon hGH-treated participants showing a statistically significant reduction from baseline in trunk fat and increase in total body lean mass at Week 38 compared to placebo. In the trial, TransCon hGH was generally safe and well tolerated, with no discontinuations related to study drug and with comparable safety and tolerability to daily hGH treatment. About Adult Growth Hormone Deficiency Growth hormone plays an essential role in the health of children and adults, promoting normal growth in children and maintenance of normal body composition and cardiometabolic health throughout adulthood. In adults, growth hormone boosts protein production, promotes fat utilization, enhances muscle mass, and helps regulate blood sugar levels. Adult GHD is a condition in which an individual’s body does not produce enough growth hormone. Symptoms and morbidity can include central obesity, metabolic syndrome, decreased bone density, alterations in lipid profile and markers of cardiovascular risk, fatigue, general weakness, lack of muscle tone, and psychological symptoms such as cognitive impairment, social isolation, lack of motivation, and depression. 1 About Ascendis Pharma A/S Ascendis Pharma is applying its innovative TransCon technology platform to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients’ lives. Guided by its core values of Patients, Science, and Passion, Ascendis uses its TransCon technologies to create new and potentially best-in-class therapies. Ascendis is headquartered in Copenhagen, Denmark and has additional facilities in Europe and the United States. Please visit ascendispharma.com to learn more. Forward-Looking Statements This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, included in this press release regarding Ascendis’ future operations, plans and objectives of management are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to (i) the PDUFA goal date for SKYTROFA, (ii) Ascendis’ objective to expand SKYTROFA’s label and reach to address new groups of patients, (iii) Ascendis’ ability to apply its TransCon technology platform to build a leading, fully integrated biopharma company, and (iv) Ascendis’ use of its TransCon technologies to create new and potentially best-in-class therapies. Ascendis may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, expectations, and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Ascendis makes, including the following: dependence on third party manufacturers, distributors and service providers for Ascendis’ products and product candidates; unforeseen safety or efficacy results in Ascendis’ development programs or on-market products; unforeseen expenses related to commercialization of any approved Ascendis products; unforeseen expenses related to Ascendis’ development programs; unforeseen selling, general and administrative expenses, other research and development expenses and Ascendis’ business generally; delays in the development of its programs related to manufacturing, regulatory requirements, speed of patient recruitment or other unforeseen delays; Ascendis’ ability to obtain additional funding, if needed, to support its business activities; the impact of international economic, political, legal, compliance, social and business factors. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Ascendis’ business in general, see Ascendis’ prospectus supplement filed on September 20, 2024 and Ascendis’ current and future reports filed with, or submitted to, the U.S. Securities and Exchange Commission (SEC), including its Annual Report on Form 20-F filed with the SEC on February 7, 2024. Forward-looking statements do not reflect the potential impact of any future licensing, collaborations, acquisitions, mergers, dispositions, joint ventures, or investments that Ascendis may enter into or make. Ascendis does not assume any obligation to update any forward-looking statements, except as required by law. Ascendis, Ascendis Pharma, the Ascendis Pharma logo, the company logo, TransCon, and SKYTROFA ® , are trademarks owned by the Ascendis Pharma group. © December 2024 Ascendis Pharma A/S. 1 . Hoffman AR, Mathison T, Andrews D, Murray K, Kelepouris N, Fleseriu M. Adult Growth Hormone Deficiency: Diagnostic and Treatment Journeys From the Patients' Perspective. J Endocr Soc. 2022;6(7):bvac077. Published 2022 May 12. doi:10.1210/jendso/bvac077WASHINGTON — Celebrities, cultural icons and a few surprise guests are gathering for the annual Kennedy Center Honors celebration Sunday evening in Washington. This year's recipients of the lifetime achievement award for artistic accomplishment are director Francis Ford Coppola, the Grateful Dead , jazz trumpeter Arturo Sandoval , and singer-songwriter Bonnie Raitt. In addition, the venerable Harlem theater The Apollo , which has launched generations of Black artists, is being recognized. There will be personalized tributes with performances and testimonials from fellow artists during the gala at the John F. Kennedy Center for the Performing Arts. Medallions were presented during the traditional Saturday night ceremony at the State Department. The tribute performances are often kept secret from the recipients themselves, most notably in 2018 when Cyndi Lauper flat out lied to her longtime friend Cher about being unable to attend. Lauper appeared on stage to perform Cher's hit, “If I Could Turn Back Time.” Several of the latest honorees have themselves participated in past tributes to friends and colleagues at the Kennedy Center. Coppola spoke during fellow director Martin Scorsese’s induction in 2007. Sandoval performed in the tribute to his mentor, jazz trumpet legend Dizzy Gillespie. Raitt has taken part in tributes to Buddy Guy and Mavis Staples. Raitt even attended the Kennedy Center Honors in the 1970s when her father, Broadway performer John Raitt, was taking part in a tribute to composer Richard Rogers. The tribute to the Grateful Dead is expected to double as a memorial to the band's founding bass player Phil Lesh , who died in October at age 84. This could also be the last Kennedy Center Honors ceremony without political intrigue for a while. During Republican Donald Trump's first four years in office, Kennedy Center officials were forced to walk a public tightrope between the tradition of the president attending the ceremony and the open antipathy toward Trump from multiple honorees. In 2017, recipient Norman Lear threatened to boycott his own ceremony if Trump attended. Trump, who takes office in January, skipped the ceremony for the entirety of his first term. Democratic President Joe Biden is scheduled to host a reception for the honorees at the White House and plans to attend the Kennedy Center ceremony afterward. The show will air on CBS on Dec. 22.MLB NOTES
Shopping on Shein and Temu for holiday gifts? You're not the only one
Another key difference is the tax implications of year-end bonuses and thirteenth-month pay. Year-end bonuses are often subject to tax deductions and may be considered as part of an employee's regular income, which can affect their overall tax liability. Thirteenth-month pay, on the other hand, is sometimes excluded from taxable income or may be taxed at a lower rate in certain jurisdictions.OTTAWA—Three key premiers whose provinces generate energy exports dismissed Premier suggestion that Canada should slap punitive tariffs on America or shut off electricity, gas and oil shipments to the U.S. in retaliation for Donald Trump’s threatened tariffs on Canadian products, as Trump shrugged off Ford’s warning. Alberta Premier Danielle Smith, Quebec Premier François Legault, and Newfoundland and Labrador’s Andrew Furey said bluntly they do not support Ford’s threat to “cut off their energy” which he said would make Americans “feel the pain.” Ford made the threat after all 13 premiers met the night before with Prime Minister Justin Trudeau on Canada’s response, and he reiterated it Thursday. However Trump, the incoming U.S. president appeared unmoved by Ford’s tough talk when speaking with a CNBC reporter Thursday on the floor of the New York Stock Exchange. “That’s OK if he that does that. That’s fine,” Trump told CNBC, repeating his about the Canada-U.S. trade deficit. “The United States is subsidizing Canada and we shouldn’t have to do that,” Trump said. “And we have a great relationship. I have so many friends in Canada, but we shouldn’t have to subsidize a country. We’re subsidizing more than a $100 billion a year. We shouldn’t have to be doing that.” Alberta’s Smith dismissed throttling Canadian energy shipments as she unveiled Alberta’s own plan to beef up border security with new provincial sheriff patrol teams to allay Trump’s border concerns. “Under no circumstances will Alberta agree to cut off oil and gas exports,” Smith said. “We don’t support tariffs. I don’t support tariffs on Canadian goods, and I don’t support tariffs on U.S. goods, because all it does is make life more expensive for everyday Canadians and everyday Americans,” Smith said. “Instead, we’re taking a diplomatic approach, and we’re meeting with our allies in the U.S. We’re making the case for Alberta oil and gas to be part of the solution to energy affordability, to energy security and to, generally speaking, North American defence security as well,” she said. Ford reiterated the notion of cutting off Canadian energy exports to the U.S. right before Quebec and Newfoundland and Labrador unveiled a blockbuster new $225-billion hydroelectricity , one those two provinces touted as key to Canada’s renewable energy commitments. The deal replaces a scorned decades-old contract due to expire in 2041, and requires Quebec to pay 30 times more for thousands of kilowatt hours of power generated from the Churchill Falls plant. It will also see the two provinces develop new hydro power projects along the Churchill River, and generate 2,400 more megawatts for Quebec. Legault called it an “extraordinary” deal for Quebec that means Labrador hydroelectricity will ramp up from a 17 per cent share of Quebec’s supply to 50 per cent. Furey said the agreement “changes everything.” “It is a fair deal for both parties. It’s a good commercial deal that recognizes the ills of the past and creates a new path forward for Newfoundland and Labrador, while allowing Quebec some certainty moving forward. So Premier Legault did show us the money,” Furey quipped. So it was no surprise when both premiers immediately dismissed any call to shut off energy exports to U.S. markets. “These tariffs will have significant impact on families and macro economies on both sides of the border. We hope it is just bluster. We’re preparing as if it is not. There will be no winners in a trade war,” Furey said, echoing Smith’s pledge. “Certainly from Newfoundland and Labrador’s perspective, we have no interest in stopping the flow of oil and gas, our incredibly valuable and now well-sought-after-world-class oil and gas to the United States. Nor do we now have any interest in stopping export of any electrons that could be produced in Labrador to the Northeastern seaboard.” Legault said he met Trump in Paris last weekend, “and he told me very clearly that we can avoid those tariffs if we do what needs to be done with the borders.” “He doesn’t want to see any more illegal immigrants coming from Canada to U.S. So I think the best choice right now for Mr. Trudeau is to very fast table a plan with money, with the number of people, to better secure the border. I think we have to do that. It’s a lot better than getting 25-per-cent tariffs starting on Jan. 21. So I prefer that than starting a war and stopping sending energy to (the) United States.” The Alberta premier said her new measures, which include sheriff patrol teams, and a “red zone” within two kilometres of the Alberta-Montana border, had been in the works since 2023 and would have been implemented even without Trump’s tariff threat. Steve Verheul, Canada’s former top trade negotiator, has suggested that Canada could put export levies on key Canadian goods like oil and agricultural commodities, saying it would quickly drive up the cost of fuel and food to American consumers, and could be used as leverage to negotiate a “broader exemption across all the sectors” that may be hit by Trump’s tariffs. Smith dismissed that, too, as a “terrible idea.” Manitoba Premier Wab Kinew said Thursday he also intends to beef up border security using provincial conservation officers and spend more on overtime for RCMP officers at the border. Kinew did not directly answer whether he would restrict electricity exports, but Kinew said Manitoba is drafting a list of potential retaliatory tariffs in order to protect Canadian jobs at risk from Trump’s tariffs. He said Canada must show “how are we going to stand up for the ag industry? How are we going to stand up for our energy industry and the manufacturing industry here in Manitoba? So we have to make sure that our response is comprehensive,” he said. But at Queen’s Park, Ford did not walk anything back. He said he’s “sending a message to the U.S.” not to impose tariffs on Canadian goods or else — as a “last resort” — Ontario will strike back. “We power 1.5 million homes,” Ford said Thursday, referring to the electricity Ontario supplies Michigan, New York and Minnesota. “If they put on tariffs, it’s going to be unaffordable for Americans to buy electricity,” the premier said, noting his province alone does about $500 billion in annual two-way trade with the U.S. and nine million American jobs depend on trading with Ontario. “Just like if they put tariffs on the 4.3 million barrels of oil that Alberta is shipping down to the U.S. — if you put 25 per cent increases, every barrel of oil, every gallon of gasoline (goes up) by $1,” he said at Queen’s Park. Ford said that “along with the federal government, all the premiers are putting a list together” of American goods that could be targeted with counter-tariffs. “We can’t just roll over as we’re being under attack and hurting our families and our jobs.” Trudeau on Monday said Canada would to Trump’s threat to impose a 25-percent surcharge on all Canadian and Mexican products on his first day in office to force the two border countries to “stop” illegal immigration and fentanyl from entering the U.S. But it is far from clear what American products the Liberal government would levy counter-tariffs on. Deputy Prime Minister Chrystia Freeland said only that several premiers said critical minerals and metals needed by the U.S. should be on any “robust” Canadian retaliatory tariff list.NEW YORK — Juan Soto put on a New York Mets jersey and cap for the first time Thursday after his record $765 million, 15-year contract was finalized and talked about what made the difference in his decision. “They showed me a lot of love. ... How they're going to make it comfortable for me,” he said. "That's one of the things I was looking for." Soto was introduced at Citi Field a day after his deal was finalized. Speaking in the Piazza 31 Club, he was flanked by Mets owner Steve Cohen, president of baseball operations David Stearns and his agent, Scott Boras. “They always talk about family. They always talk about stick(ing) together,” Soto said. “That's one of the things that opened my eyes.” Security men in gray suits wearing earpieces were off to the side. Soto walked in led by Boras, wearing a dark suit, black turtle neck shirt and gold chain with his No. 22. “I’m excited by the Mets future,” Cohen said. “I think this accelerates our goal of winning championships.” Soto chose the Mets' offer on Sunday, deciding to leave the Yankees after helping them reach the World Series in his only season in the Bronx. SAN FRANCISCO — Willy Adames wasted little time making one thing clear: He wants to play all 162 games for the San Francisco Giants. So when introduced as their new shortstop Thursday, Adames looked to his left and gently put a hand on manager Bob Melvin's right shoulder, smiled and said, “if he lets me.” Melvin might not need much convincing, thrilled to suddenly have stability at a position that lacked continuity this year in his first season as skipper. Adames didn't hesitate to also offer a thought to new boss Buster Posey: He plans to win a few championships with the Giants just like the catcher-turned-executive did here. Surrounded by his parents and other family and friends, Adames was formally introduced and welcomed at Oracle Park after signing a $182 million, seven-year contract — the first big, splashy move made by Posey since he became President of Baseball Operations in late September. “There’s no words to describe my feeling right now to be here in this beautiful city, I’m just so happy to be here,” Adames said. "... This is a dream come true for me. I’m thrilled to be here, I’m so excited. Hopefully we can win a few championships like you did, and that’s one of the main reasons I’m here.” PUERTO PLATA, Dominican Republic — The trial against Tampa Bay Rays shortstop Wander Franco, who has been charged with sexually abusing a minor, sexual and commercial exploitation against a minor, and human trafficking, was postponed on Thursday and scheduled to resume June 2, 2025. Dominican judge Yacaira Veras postponed the hearing at the request of prosecutors because of the absence of several key witnesses in the case. Only three out of 31 witnesses arrived to the hearing on Thursday. Franco’s lawyers asked the court to reconsider the postponement, arguing Franco must report to spring training in mid-February. “There is no case against Wander, for as many witnesses as they present, there is no case now,” Franco's lead lawyer Teodosio Jáquez told The Associated Press after the hearing. The judge replied that Franco is obligated to continue with the trial schedule and his conditional release from detainment. Get local news delivered to your inbox!
The concept of "extraordinary counter-cyclical adjustment" refers to measures taken by the government to stabilize the economy during periods of economic downturn or recession. These measures typically involve increasing government spending, providing targeted stimulus packages, and implementing structural reforms to boost economic activity and employment. By strengthening these measures, policymakers aim to prevent a sharp economic decline and mitigate the negative impacts of external shocks or internal imbalances.
Shopping on Shein and Temu for holiday gifts? You're not the only one
(The Center Square) – Homeowners in the market for washers and dryers may have better-performing options to choose from in the near future due to a bill limiting the extent of energy efficiency mandates on laundry appliances passing the U.S. House. The Republican-led House Resolution 1612 , or Liberty in Laundry Act, would prohibit the Secretary of Energy from enforcing energy conservation standards for clothes washers or dryers that “are not cost-effective or technologically feasible.” Rep. Andy Ogles, R-Tenn., who introduced the legislation, said the move is a response to the “slew of woke, ‘environmental’ nonsense rulemaking attempts” by the Biden administration and U.S. Department of Energy. “I have spent much of my time in Congress fighting back the federal government’s vast overreach into the lives of hardworking Americans,” Ogles announced after the bill’s passage Tuesday. “Americans should be able to do their laundry in peace without the input of Big Brother.” Earlier this year, the DOE finalized new updated standards for residential clothes washers and dryers which aim to cut costs and pollution. It estimates the regulations will reduce nearly 71 million metric tons of carbon dioxide emissions–equivalent to the combined annual emissions of nearly 9 million homes–and up to $39 billion on Americans’ energy and water bills over the next 30 years. House Democrats opposed the legislation's passage, saying "absolutely no one" stands to benefit from the law and accused Republicans of trying to curry favor with special interest groups. "H.R. 7673 guts popular energy efficiency standards for laundry machines – standards that save Americans money on their utility bills and reduce dangerous greenhouse gas pollution at the same time," said Energy and Commerce Committee Ranking Member Frank Pallone, Jr., D-N.J. "These efficiency standards create certainty for manufacturers and they protect consumers from rising costs. And, in the case of these laundry machine standards, they also reduce water use – a benefit that could greatly aid drought-prone regions around the nation." But the less electricity and water laundry appliances use, the less effectively they tend to perform, according to an Oct. 2024 report by the Institute for Energy Research. “Historically, appliances meeting Energy Department standards have often underperformed and have higher costs,” the report stated. “The Biden-Harris administration is imposing a series of regulations that are raising appliance prices and compromising quality for homeowners.” Unless the bill is signed into law, laundry appliance makers have until March 2028 to comply with the new rules.
Isra’ila ta shirya kai hari cibiyoyin makaman nukiliyar Iran
For fans of the show, this collaboration represents a unique opportunity to bring a piece of their favorite animated series into their daily lives. The designs on the Pepsi bottles showcase iconic characters and scenes from "The Legend of Sun Wukong: A Myth of Black," making them a must-have collectible for enthusiasts of the series.Moreover, the AI Director Collaboration Plan also includes a series of workshops, training sessions, and collaborative projects that bring together filmmakers, AI experts, and social impact organizations to explore the potential of AI technology in driving positive change and creating impactful content.But the question remains - would you buy it? Is the allure of a limited edition co-branded product enough to convince consumers to part ways with their hard-earned money? Let's delve deeper into the factors that might influence a consumer's decision.
Chargers QB Justin Herbert does not practice because of left ankle injury
Another key difference is the tax implications of year-end bonuses and thirteenth-month pay. Year-end bonuses are often subject to tax deductions and may be considered as part of an employee's regular income, which can affect their overall tax liability. Thirteenth-month pay, on the other hand, is sometimes excluded from taxable income or may be taxed at a lower rate in certain jurisdictions.Erdoğan receives Blinken for talks on post-Assad Syria
NEW YORK — Juan Soto put on a New York Mets jersey and cap for the first time Thursday after his record $765 million, 15-year contract was finalized and talked about what made the difference in his decision. “They showed me a lot of love. ... How they're going to make it comfortable for me,” he said. "That's one of the things I was looking for." Soto was introduced at Citi Field a day after his deal was finalized. Speaking in the Piazza 31 Club, he was flanked by Mets owner Steve Cohen, president of baseball operations David Stearns and his agent, Scott Boras. “They always talk about family. They always talk about stick(ing) together,” Soto said. “That's one of the things that opened my eyes.” Security men in gray suits wearing earpieces were off to the side. Soto walked in led by Boras, wearing a dark suit, black turtle neck shirt and gold chain with his No. 22. “I’m excited by the Mets future,” Cohen said. “I think this accelerates our goal of winning championships.” Soto chose the Mets' offer on Sunday, deciding to leave the Yankees after helping them reach the World Series in his only season in the Bronx. SAN FRANCISCO — Willy Adames wasted little time making one thing clear: He wants to play all 162 games for the San Francisco Giants. So when introduced as their new shortstop Thursday, Adames looked to his left and gently put a hand on manager Bob Melvin's right shoulder, smiled and said, “if he lets me.” Melvin might not need much convincing, thrilled to suddenly have stability at a position that lacked continuity this year in his first season as skipper. Adames didn't hesitate to also offer a thought to new boss Buster Posey: He plans to win a few championships with the Giants just like the catcher-turned-executive did here. Surrounded by his parents and other family and friends, Adames was formally introduced and welcomed at Oracle Park after signing a $182 million, seven-year contract — the first big, splashy move made by Posey since he became President of Baseball Operations in late September. “There’s no words to describe my feeling right now to be here in this beautiful city, I’m just so happy to be here,” Adames said. "... This is a dream come true for me. I’m thrilled to be here, I’m so excited. Hopefully we can win a few championships like you did, and that’s one of the main reasons I’m here.” PUERTO PLATA, Dominican Republic — The trial against Tampa Bay Rays shortstop Wander Franco, who has been charged with sexually abusing a minor, sexual and commercial exploitation against a minor, and human trafficking, was postponed on Thursday and scheduled to resume June 2, 2025. Dominican judge Yacaira Veras postponed the hearing at the request of prosecutors because of the absence of several key witnesses in the case. Only three out of 31 witnesses arrived to the hearing on Thursday. Franco’s lawyers asked the court to reconsider the postponement, arguing Franco must report to spring training in mid-February. “There is no case against Wander, for as many witnesses as they present, there is no case now,” Franco's lead lawyer Teodosio Jáquez told The Associated Press after the hearing. The judge replied that Franco is obligated to continue with the trial schedule and his conditional release from detainment. Be the first to know Get local news delivered to your inbox!In a much-anticipated announcement, the highly acclaimed anime series "Demon Slayer" is set to captivate audiences once again with its upcoming theatrical release of the "Infinity Castle Arc" in 2025. Fans worldwide have been eagerly awaiting the next chapter in the gripping tale of Tanjiro Kamado and his companions as they continue their battle against the demons that threaten humanity.FRANKFORT, Ky. (AP) — Looking for hard-to-find bottles of Kentucky bourbon to toast the holidays or add to a collection? Get your bids ready as the Bluegrass State launches its first online auction of confiscated alcohol. Whiskeys up for sale include two bottles of Old Rip Van Winkle, a Blanton’s Single Barrel Gold in box with Japanese markings and a bottle of Four Roses Small Batch Barrel Strength 2011. The sale is the result of a new Kentucky law, which allows alcohol confiscated from closed criminal investigations by the state's alcoholic beverage control agency to be auctioned. Online bidding opens Wednesday and closes at midnight on Dec. 11. Proceeds will support programs promoting responsible alcohol use by adults and awareness programs for youths. “This is a really good auction,” Eric Gregory, president of the Kentucky Distillers’ Association, said by phone Tuesday. “There are some hard-to-find and rare bottles on there.” No estimate has been given on how much the auction might raise. “We look forward to seeing the response to this auction and have started planning additional auctions for 2025,” said Allyson Taylor, commissioner of the Kentucky Department of Alcoholic Beverage Control. The auction features 32 bottles of alcohol and includes a “stock the bar” bundle with bottles of wine, vodka, rum and whiskey, the agency said. But the stars are the hard-to-find and rare bourbons up for sale. “It’s not every day you go to a liquor store and find a bottle of Blanton’s Gold," Gregory said. “You never go to a liquor store and find a bottle of Four Roses 2011.” The lineup includes bottles of E.H. Taylor bourbon, Blanton’s Single Barrel, Eagle Rare 10 yr., Weller Antique 107, Willett Family Estate Single Barrel Rye, Michter’s, an Old Forester gift set and more. A link to the online auction is available at ABC.ky.gov . Auction items cannot be shipped, so winning bidders must pick up items in Frankfort, the state said. The auctions will become a “can't miss opportunity” for bourbon connoisseurs, Gregory said. Previously, confiscated bourbon or other spirits could end up being destroyed, he said. “We don't like to see good bourbon poured down the drain,” Gregory said. Kentucky distillers produce 95% of the global bourbon supply, the Kentucky distillers’ group says.
NASHVILLE, Tenn. — The University of South Dakota women’s basketball team notched a season-high scoring output en route to a 79-69 victory over Dayton on Tuesday during the first of two games for the Coyotes at the Music City Classic. Grace Larkins and Alexi Hempe paced the Coyotes with big performances. Larkins matched a career-high with 34 points on 50% shooting from the field with seven rebounds as well. Meanwhile, Hempe scored a career-high 23 points in the matchup to go along with eight rebounds of her own. ADVERTISEMENT The Coyotes got out to an early advantage of 19-9 through the first quarter with a stifling defense that only allowed the Flyers to shoot 22% from the field in the opening 10 minutes. The advantage grew by halftime, with USD leading 41-29 at the intermission. Dayton was the team to come out of the locker room on the front to start the third quarter though. The Flyers began to close the gap, hitting as many field goals in the third quarter as they did in the first two combined. However, the Coyotes still held a 59-52 advantage thanks to seven points from Hempe in the final four minutes of the quarter. Larkins and Hempe stayed hot as the two combined for 13 of the Coyotes' 20 points in the fourth quarter as they went on to close out the Flyers for their third win of the season and third straight. For Dayton, Nicole Stephens led the way with 15 points, Arianna Smith was right behind with 14 points of her own, while Ivy Wolf also finished in double-figures with 13. USD (3-4) will finish out the Music City Classic against Arizona State at 11 a.m. Wednesday.
Commentary: Outrage jolts health insurersN.Y., N.J. senators pen letter to feds, Homeland Security, FAA requesting drone activity briefing