PALO ALTO, Calif., Dec. 27, 2024 (GLOBE NEWSWIRE) -- Vincerx Pharma, Inc. (Nasdaq: VINC), a biopharmaceutical company aspiring to address the unmet medical needs of patients with cancer through paradigm-shifting therapeutics, today announced that it has entered into a binding term sheet for a proposed merger with Oqory, Inc., a privately-held, clinical-stage company developing ADCs for the treatment of multiple oncology indications. Upon completion of the proposed merger, Oqory, Inc. will merge with Vincerx Pharma, Inc. Post-closing, Oqory equity holders are expected to own approximately 95% of the combined entity, while Vincerx equity holders will hold about 5%. The transaction includes a minimum fully diluted equity value of $13.66 million for existing Vincerx stockholders at closing and, as a condition to the closing of the merger, completion of a concurrent offering of Vincerx equity securities of at least $20 million. Additionally, Oqory-designated investors will provide interim financing to Vincerx of $1.5 million in two tranches, approximately $1,000,000 of which was funded today through the issuance of common stock and pre-funded warrants along with accompanying common stock warrants and approximately $500,000 of which will be funded on or prior to January 31, 2025. The merger is subject to customary closing conditions, including due diligence, regulatory approvals, negotiation of a definitive merger agreement, stockholder approval from both parties, completion of the minimum $20 million financing, and the continued listing of Vincerx's common stock on Nasdaq. Vincerx is also implementing additional streamlining and cost-control measures, including a workforce reduction, as it pursues due diligence and transaction-related work. As part of this workforce reduction, Dr. Ahmed Hamdy, Chairman and Chief Executive Officer (CEO), has stepped down as CEO but will remain as Chairman. Dr. Raquel Izumi has stepped down as President and Chief Operations Officer and taken over as Acting CEO in a consulting capacity. Alexander Seelenberger has stepped down as Chief Financial Officer, and Kevin Hass, the Company’s Vice President and Controller, has taken over as Acting Chief Financial Officer. Mr. Seelenberger has agreed to provide ongoing assistance in a consulting capacity to assist the Company as it pursues its strategic efforts. “This strategic transaction highlights Vincerx’s commitment to develop ADCs with improved safety profiles that allow patients to thrive on—rather than endure—their cancer therapies,” said Raquel Izumi, Ph.D., Acting Chief Executive Officer. “Oqory’s anti-TROP2 ADC has shown favorable efficacy and safety in the clinic. Among approximately 150 treated patients, results include an 83% overall response rate and 100% disease control rate in first-line triple-negative breast cancer (TNBC; n=30). Unlike other TROP2 ADCs in Phase 3, no cases of interstitial lung disease or Grade 3 and above stomatitis have been reported. Oqory’s Phase 3 studies of OQY-3258 are ongoing to confirm these promising findings.” About OQY-3258 (also known as ESG401) OQY-3258 is Oqory’s anti-TROP2 ADC with an optimized enzyme-dependent linker technology and an SN-38 payload with established efficacy and manageable side effect profile. OQY-3258 has completed Phase 1/2 development in over 150 patients with solid tumors, including metastatic HR+/HER2- and triple-negative breast cancer. OQY-3258 has shown efficacy in these patients, including reduction of brain metastasis and responses in heavily pretreated patients. To date, OQY-3258 has exhibited a differentiated safety profile vs. Trodelvy and other TROP2 ADCs in Phase 3 development. Notably, no interstitial lung disease or ocular surface events have been observed. Gastrointestinal effects have been mild and mainly Grade 1/2. Neutropenia and leukopenia have been the major AEs, which were manageable and did not result in discontinuation of study drug. OQY-3258 is being evaluated in a Phase 3 study as first-line treatment in patients with unresectable recurrent or metastatic triple-negative breast cancer ( NCT06732323 ) and in a Phase 3 study in patients with unresectable locally advanced or metastatic HR+/HER2- breast cancer ( NCT06383767 ). About Oqory, Inc. Oqory, Inc. is an innovator in the field of ADCs with expertise in advancing targeted cancer therapies. The Company’s pipeline includes multiple ADC programs, with two currently in clinical development and several next-generation ADCs in preclinical stages. These programs are designed to address critical unmet needs in indications such as breast cancer, non-small cell lung cancer, small cell lung cancer, multiple myeloma, and other metastatic solid tumors. Powered by a proprietary ADC platform, Oqory is delivering therapies that have demonstrated promising efficacy and safety paving the way for improved patient outcomes. About Vincerx Pharma, Inc. Vincerx Pharma, Inc. is a clinical-stage biopharmaceutical company committed to developing differentiated and novel therapies to address the unmet medical needs of patients with cancer. Vincerx’s pipeline consists of a next-generation ADC, VIP943, currently in Phase 1; a small molecule drug conjugate, VIP236, which has completed its Phase 1 study; a CDK9 inhibitor, enitociclib, which has completed a Phase 1 monotherapy study; a preclinical ADC, VIP924; and VersAptxTM, a versatile, next-generation bioconjugation platform. Vincerx is based in Palo Alto, California, and has a research subsidiary in Monheim, Germany. Forward-Looking Statements This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the Securities Act), and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the “safe harbor” created by those sections. Forward-looking statements, which are based on certain assumptions and describe future plans, strategies, expectations and events, can generally be identified by the use of forward-looking terms such as “believe,” “expect,” “may,” “will,” “should,” “would,” “could,” “suggest,” “seek,” “intend,” “plan,” “goal,” “potential,” “on-target,” “on track,” “project,” “estimate,” “anticipate,” or other comparable terms. All statements other than statements of historical facts included in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, the entry into a definitive merger agreement; the anticipated terms and closing of the merger, the $20 million equity investment, and the amount and timing of the interim financing; the expected ownership structure and value to Vincerx stockholders upon closing of the merger; the anticipated benefits of a merger transaction; and the clinical results of Oqory’s product candidates. Forward-looking statements are neither historical facts nor assurances of future performance or events. Instead, they are based only on current beliefs, expectations, and assumptions regarding future business developments, future plans and strategies, projections, anticipated events and trends, the economy, and other future conditions. Forward-looking statements are subject to inherent uncertainties, risks, and changes in circumstances that are difficult to predict, many of which are outside Vincerx’s control. Actual results, conditions, and events may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause actual results, conditions, and events to differ materially from those indicated in the forward-looking statements include, but are not limited to, Vincerx’s capital requirements, availability and sufficiency of capital, and cash runway; the ability of the parties to enter into a definitive merger agreement and the final terms thereof; the parties’ ability to satisfy the conditions precedent to the merger, including stockholder approval; the closing of the merger; the risk that any definitive agreement is terminated after it is entered into but before consummation of any proposed merger;; Vincerx’s reliance on receipt of interim funding; market acceptance of the combined company; risks associated with clinical development of the Vincerx and Oqory product candidates; general economic, financial, legal, political, and business conditions; and the risks and uncertainties set forth in Vincerx’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2024 and subsequent reports filed with the Securities and Exchange Commission by Vincerx. Forward-looking statements speak only as of the date hereof, and Vincerx disclaims any obligation to update any forward-looking statements. Vincerx and the Vincerx logo are trademarks of Vincerx. This press release also contains trademarks and trade names that are the property of their respective owners. Contacts: Gabriela Jairala Vincerx Pharma, Inc. gabriela.jairala@vincerx.com Totyana Simien Inizio Evoke Comms totyana.simien@inizioevoke.comUnlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access. It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
Trump's casting call as he builds out his administration: TV experience preferredFormer Tulane quarterback Darian Mensah has already found a new program in Duke, while Mississippi State's Michael Van Buren Jr., Wisconsin's Braedyn Locke and Cal's Fernando Mendoza are exploring changes of their own in the transfer portal. Mensah, a redshirt freshman with three years of eligibility remaining, told ESPN on Wednesday he has transferred to Duke. He attended the Blue Devils men's basketball game against Incarnate Word on Tuesday night. The Blue Devils (9-3) will face Mississippi in the Gator Bowl, but without 2024 starting quarterback Maalik Murphy and backup Grayson Loftis, who also entered the portal. Mensah, viewed as one of the top players in the portal, threw for 2,723 yards and 22 touchdowns and completed 65.9% of his passes. He led the Green Wave to a 9-4 record and the American Athletic Conference championship game, where they lost 35-14 to Army. Tulane will play Florida in the Gasparilla Bowl on Sunday. Van Buren, Mendoza and Locke announced on social media they had entered the portal. Van Buren started eight games as a true freshmen for the Bulldogs. He threw for 1,886 yards on 55% passing with 16 total touchdowns and seven interceptions for the Bulldogs (2-10, 0-8 Southeastern Conference). He took over as the starter when Blake Shapen suffered a season-ending shoulder injury in a 45-28 loss to Florida on Sept. 21. Shapen has said he plans to return next season. Van Buren, a 6-foot-1, 200-pound passer from St. Frances Academy in Maryland, had two 300-yard performances for the Bulldogs, including 306 yards and three touchdown passes in a 41-31 road loss against Georgia. Mendoza threw for 3,004 yards in 2024 with 16 TDs, six interceptions and a 68.7 completion percentage. "For the sake of my football future this is the decision I have reached," he posted. Locke passed for 1,936 yards with 13 touchdowns and 10 interceptions for Wisconsin this season. He said he will have two years of eligibility remaining at his next school. ANN ARBOR, Mich. — Michigan cornerback Will Johnson has joined defensive tackle Mason Graham in the NFL draft. Johnson declared for the draft on Wednesday, one day after Graham decided he would also skip his senior season with the Wolverines. Both preseason All-America players are expected to be first-round picks. Johnson was limited to six games this year due to an injury. He had two interceptions, returning them both for touchdowns to set a school record with three scores off interceptions. Johnson picked off nine passes in three seasons. Graham played in all 12 games this season, finishing with 3 1/2 sacks and seven tackles for losses. He had 18 tackles for losses, including nine sacks, in his three-year career. Tennessee running back Dylan Sampson is The Associated Press offensive player of the year in the Southeastern Conference and South Carolina defensive lineman Kyle Kennard is the top defensive player. Vanderbilt quarterback Diego Pavia was voted the top newcomer on Wednesday while the Gamecocks' Shane Beamer is coach of the year in voting by the panel of 17 media members who cover the league. Sampson led the SEC and set school records by rushing for 1,485 yards and 22 touchdowns. He is tied for third nationally in rushing touchdowns, recording the league's fifth-most in a season. Sampson was chosen on all but two ballots. Mississippi wide receiver Tre Harris and his quarterback, Jaxson Dart, each got a vote. Kennard led the SEC with 11-1/2 sacks and 15-1/2 tackles for loss. He also had 10 quarterback hurries and forced three fumbles. Beamer led the Gamecocks to just their fifth nine-win season, including a school-record four wins over Top 25 opponents. They've won their last six games and ended the regular season with a win over eventual ACC champion Clemson. South Carolina plays Illinois on Dec. 31 in the Citrus Bowl. Pavia helped lead Vandy to its first bowl game since 2018 after transferring from New Mexico State. He passed for 2,133 yards and 17 touchdowns with four interceptions. He ran for another 716 yards and six touchdowns, directing an upset of Alabama. AMES, Iowa — Matt Campbell, who led Iowa State to its first 10-win season and became the program's all-time leader in coaching victories, has agreed to an eight-year contract that would keep him with the Cyclones through 2032. University president Wendy Wintersteen and athletic director Jamie Pollard made the announcement Wednesday, four days after the Cyclones lost to Arizona State in the Big 12 championship game. “Given all the uncertainty currently facing college athletics, it was critical that we moved quickly to solidify the future of our football program,” Pollard said. “Matt is the perfect fit for Iowa State University and I am thrilled he wants to continue to lead our program. Leadership continuity is essential to any organization’s long-term success." The Cyclones won their first seven games for their best start since 1938 and are 10-3 heading into their game against Miami in the Pop Tarts Bowl in Orlando, Florida, on Dec. 28. BRIEFLY FLAG PLANT: Ohio Republican state Rep. Josh Williams said Wednesday on social media he's introducing a bill to make flag planting in sports a felony in the state. His proposal comes after the Nov. 30 fight at the Michigan-Ohio State rivalry football game when the Wolverines beat the Buckeyes 13-10 and then attempted to plant their flag at midfield. MALZAHN: Gus Malzahn, who resigned as UCF’s coach last month to become Mike Norvell’s offensive coordinator at Florida State, said he chose to return to his coaching roots rather than remain a head coach distracted by a myriad of responsibilities. Get local news delivered to your inbox!
TORONTO, Dec. 27, 2024 (GLOBE NEWSWIRE) -- Abaxx Technologies Inc., (CBOE: ABXX) (OTCQX: ABXXF) (“ Abaxx ” or the “ Company ”), a financial software and market infrastructure company, indirect majority shareholder of Abaxx Singapore Pte Ltd. (“ Abaxx Singapore ”), the owner of Abaxx Commodity Exchange and Clearinghouse (individually, “ Abaxx Exchange ” and “ Abaxx Clearing ”), and producer of the SmarterMarketsTM Podcast, today announces that it has filed an early warning report in respect of MineHub Technologies Inc. (“ MineHub ”). On December 27, 2024, pursuant to a share purchase agreement between Abaxx and MineHub dated December 3, 2024 (the “ SPA ”), Abaxx acquired 8,810,000 common shares of MineHub (“ MineHub Shares ”). Prior to the closing of the SPA (the “ Closing ”), Abaxx held 8,333,333 MineHub Shares representing 10.83% of the issued and outstanding MineHub Shares on an undiluted and a partially diluted basis. Immediately after Closing, Abaxx held 17,143,333 MineHub Shares, representing 19.87% of the issued and outstanding MineHub Shares on an undiluted and a partially diluted basis. As a result of the MineHub Shares issued in connection with the SPA, Abaxx’s holdings have changed by more than 2% on a partially diluted basis since the filing of its previous early warning report. The MineHub Shares held by Abaxx are for investment purposes. In accordance with applicable securities laws, Abaxx may, from time to time and at any time, acquire additional shares and/or other equity, debt or other securities or instruments of MineHub in the open market or otherwise, and reserves the right to dispose of any or all of such securities in the open market or otherwise at any time and from time to time, and to engage in similar transactions with respect to such securities, the whole depending on market conditions, the business and prospects of MineHub and other relevant factors. This disclosure is issued pursuant to National Instrument 62-103 - The Early Warning System and Related Take-Over Bid and Insider Reporting Issues , which also requires an early warning report to be filed with the applicable securities regulators containing additional information with respect to the foregoing matters. A copy of the early warning report will be filed by Abaxx under MineHub’s profile on SEDAR+ at www.sedarplus.com or may be obtained at Abaxx’s head office address at 110 Young St., Suite 1601, Toronto, Ontario M5C 1T4. The MineHub Shares are listed on the TSX Venture Exchange under the symbol “MHUB”. MineHub is a corporation existing under the laws of British Columbia with its head office at Suite 918 - 1030 West Georgia St., Vancouver, British Columbia, V6E 2Y3, Canada. About Abaxx Technologies Abaxx is building Smarter Markets — markets empowered by better financial technology and market infrastructure to address our biggest challenges, including the energy transition. In addition to developing and deploying financial technologies that make communication, trade, and transactions easier and more secure, Abaxx is an indirect majority-owner of subsidiaries Abaxx Exchange and Abaxx Clearing, recognized by MAS as a “recognised market operator” (RMO) and “approved clearing house” (ACH), respectively. Abaxx Exchange and Abaxx Clearing are a Singapore-based commodity futures exchange and clearinghouse, introducing centrally cleared, physically deliverable commodities futures and derivatives to provide better price discovery and risk management tools for the commodities critical to our transition to a lower-carbon economy. For more information please visit abaxx.tech , abaxx.exchange and smartermarkets.media . Media and investor inquiries: Abaxx Technologies Inc. Investor Relations Team Tel: +1 246 271 0082 E-mail: ir@abaxx.tech Cautionary Statement Regarding Forward-Looking Information This press release includes certain “forward-looking statements” which do not consist of historical facts. Forward-looking statements include estimates and statements that describe Abaxx’s future plans, objectives, or goals, including words to the effect that Abaxx expects a stated condition or result to occur. Forward-looking statements may be identified by such terms as “seeking”, “should”, “intend”, “predict”, “potential”, “believes”, “anticipates”, “expects”, “estimates”, “may”, “could”, “would”, “will”, “continue”, “plan” or the negative of these terms and similar expressions. Since forward-looking statements are based on current expectations and assumptions and address future events and conditions, by their very nature they involve inherent risks and uncertainties. Although these statements are based on information currently available to Abaxx, Abaxx does not provide any assurance that actual results will meet respective management expectations. Risks, uncertainties, assumptions, and other factors involved with forward-looking information could cause actual events, results, performance, prospects, and opportunities to differ materially from those expressed or implied by such forward-looking information. Forward-looking information related to Abaxx in this press release includes but is not limited to, Abaxx’s objectives, goals, and future plans. Forward-looking statements are necessarily based upon a number of estimates and assumptions including material estimates and assumptions related to the factors set forth below that, while considered reasonable by Abaxx as at the date of this press release in light of management’s experience and perception of current conditions and expected developments, are inherently subject to significant business, economic and competitive uncertainties and contingencies. Such factors impacting forward-looking information include, among others: risks relating to the global economic climate and extreme weather events; dilution; Abaxx’s limited operating history; future capital needs and uncertainty of additional financing; the competitive nature of the industry; currency exchange risks; the need for Abaxx to manage its planned growth and expansion; the effects of product development and need for continued technology change; protection of proprietary rights; the effect of government regulation and compliance on Abaxx and the industry; regulatory risks in Singapore and Canada; the ability to list Abaxx’s securities on stock exchanges in a timely fashion or at all; network security risks; the ability of Abaxx to maintain properly working systems; reliance on key personnel; global economic and financial market deterioration impeding access to capital or increasing the cost of capital; taxation; resource shortages; damage to the Company’s reputation due to the actual or perceived occurrence of any number of events, including negative publicity with respect to the Company’s operations, whether true or not; risk of loss due to acts of war, terrorism, sabotage and civil disturbances; the impact of inflation, including global energy cost increases; and volatile securities markets impacting security pricing unrelated to operating performance. In addition, particular factors which could impact future results of the business of Abaxx include but are not limited to: operations in foreign jurisdictions, protection of intellectual property rights, contractual risk, third-party risk; clearinghouse risk, malicious actor risks, third-party software license risk, system failure risk, risk of technological change; dependence of technical infrastructure; changes in the price of commodities, capital market conditions and restriction on labor and international travel and supply chains. Abaxx has also assumed that no significant events occur outside of Abaxx’s normal course of business. Abaxx cautions that the foregoing list of material factors is not exhaustive. In addition, although Abaxx has attempted to identify important factors that could cause actual results to differ materially, there may be other factors that cause results not to be as anticipated, estimated, or intended. When relying on forward-looking statements and information to make decisions, investors and others should carefully consider the foregoing factors and other uncertainties and potential events. Readers are cautioned that forward-looking statements are not guarantees of future performance. Abaxx has assumed that the material factors referred to in the previous paragraphs will not cause such forward-looking statements and information to differ materially from actual results or events. However, the list of these factors is not exhaustive and is subject to change and there can be no assurance that such assumptions will reflect the actual outcome of such items or factors. The forward-looking statements and information contained in this press release represents the expectations of Abaxx as of the date of this press release and, accordingly, is subject to change after such date. Abaxx undertakes no obligation to update or revise any forward-looking statements and information, whether as a result of new information, future events or otherwise, except as required by law. Accordingly, readers are cautioned not to place undue reliance on these forward-looking statements and information. Cboe Canada does not accept responsibility for the adequacy or accuracy of this press release.Police deny sitting on evidence as Netflix doc brings renewed attention to JonBenet Ramsey's killingAP Business SummaryBrief at 6:15 p.m. EST
Former Tulane quarterback Darian Mensah has already found a new program in Duke, while Mississippi State's Michael Van Buren Jr., Wisconsin's Braedyn Locke and Cal's Fernando Mendoza are exploring changes of their own in the transfer portal. Mensah, a redshirt freshman with three years of eligibility remaining, told ESPN on Wednesday he has transferred to Duke. He attended the Blue Devils men's basketball game against Incarnate Word on Tuesday night. The Blue Devils (9-3) will face Mississippi in the Gator Bowl, but without 2024 starting quarterback Maalik Murphy and backup Grayson Loftis, who also entered the portal. Mensah, viewed as one of the top players in the portal, threw for 2,723 yards and 22 touchdowns and completed 65.9% of his passes. He led the Green Wave to a 9-4 record and the American Athletic Conference championship game, where they lost 35-14 to Army. Tulane will play Florida in the Gasparilla Bowl on Sunday. Van Buren, Mendoza and Locke announced on social media they had entered the portal. Van Buren started eight games as a true freshmen for the Bulldogs. He threw for 1,886 yards on 55% passing with 16 total touchdowns and seven interceptions for the Bulldogs (2-10, 0-8 Southeastern Conference). He took over as the starter when Blake Shapen suffered a season-ending shoulder injury in a 45-28 loss to Florida on Sept. 21. Shapen has said he plans to return next season. Van Buren, a 6-foot-1, 200-pound passer from St. Frances Academy in Maryland, had two 300-yard performances for the Bulldogs, including 306 yards and three touchdown passes in a 41-31 road loss against Georgia. Mendoza threw for 3,004 yards in 2024 with 16 TDs, six interceptions and a 68.7 completion percentage. "For the sake of my football future this is the decision I have reached," he posted. Locke passed for 1,936 yards with 13 touchdowns and 10 interceptions for Wisconsin this season. He said he will have two years of eligibility remaining at his next school. ANN ARBOR, Mich. — Michigan cornerback Will Johnson has joined defensive tackle Mason Graham in the NFL draft. Johnson declared for the draft on Wednesday, one day after Graham decided he would also skip his senior season with the Wolverines. Both preseason All-America players are expected to be first-round picks. Johnson was limited to six games this year due to an injury. He had two interceptions, returning them both for touchdowns to set a school record with three scores off interceptions. Johnson picked off nine passes in three seasons. Graham played in all 12 games this season, finishing with 3 1/2 sacks and seven tackles for losses. He had 18 tackles for losses, including nine sacks, in his three-year career. Tennessee running back Dylan Sampson is The Associated Press offensive player of the year in the Southeastern Conference and South Carolina defensive lineman Kyle Kennard is the top defensive player. Vanderbilt quarterback Diego Pavia was voted the top newcomer on Wednesday while the Gamecocks' Shane Beamer is coach of the year in voting by the panel of 17 media members who cover the league. Sampson led the SEC and set school records by rushing for 1,485 yards and 22 touchdowns. He is tied for third nationally in rushing touchdowns, recording the league's fifth-most in a season. Sampson was chosen on all but two ballots. Mississippi wide receiver Tre Harris and his quarterback, Jaxson Dart, each got a vote. Kennard led the SEC with 11-1/2 sacks and 15-1/2 tackles for loss. He also had 10 quarterback hurries and forced three fumbles. Beamer led the Gamecocks to just their fifth nine-win season, including a school-record four wins over Top 25 opponents. They've won their last six games and ended the regular season with a win over eventual ACC champion Clemson. South Carolina plays Illinois on Dec. 31 in the Citrus Bowl. Pavia helped lead Vandy to its first bowl game since 2018 after transferring from New Mexico State. He passed for 2,133 yards and 17 touchdowns with four interceptions. He ran for another 716 yards and six touchdowns, directing an upset of Alabama. AMES, Iowa — Matt Campbell, who led Iowa State to its first 10-win season and became the program's all-time leader in coaching victories, has agreed to an eight-year contract that would keep him with the Cyclones through 2032. University president Wendy Wintersteen and athletic director Jamie Pollard made the announcement Wednesday, four days after the Cyclones lost to Arizona State in the Big 12 championship game. “Given all the uncertainty currently facing college athletics, it was critical that we moved quickly to solidify the future of our football program,” Pollard said. “Matt is the perfect fit for Iowa State University and I am thrilled he wants to continue to lead our program. Leadership continuity is essential to any organization’s long-term success." The Cyclones won their first seven games for their best start since 1938 and are 10-3 heading into their game against Miami in the Pop Tarts Bowl in Orlando, Florida, on Dec. 28. BRIEFLY FLAG PLANT: Ohio Republican state Rep. Josh Williams said Wednesday on social media he's introducing a bill to make flag planting in sports a felony in the state. His proposal comes after the Nov. 30 fight at the Michigan-Ohio State rivalry football game when the Wolverines beat the Buckeyes 13-10 and then attempted to plant their flag at midfield. MALZAHN: Gus Malzahn, who resigned as UCF’s coach last month to become Mike Norvell’s offensive coordinator at Florida State, said he chose to return to his coaching roots rather than remain a head coach distracted by a myriad of responsibilities. Get local news delivered to your inbox!
LONDON — Pooches in pullovers paraded past Buckingham Palace on Saturday for a gathering of dogs in Christmas sweaters to raise funds for rescue charities. People and dogs take part in the Rescue Dogs of London and Friends Christmas Jumper Parade on Saturday outside Buckingham Palace in central London. James Manning, PA About 130 pets, and their owners, walked Saturday from St. James's Park and along the Mall, the wide boulevard that leads to the royal palace as part of the Christmas Jumper Parade. Flossie the dog barks Saturday during the Rescue Dogs of London and Friends Christmas Jumper Parade in central London. James Manning, PA Prizes were awarded for best-dressed pets, with contenders including canine Santas, puppy elves and a French bulldog dressed in a red beret and pink jacket adorned with red bows. People and dogs take part in the Rescue Dogs of London and Friends Christmas Jumper Parade on Saturday in central London. James Manning, PA The event was organized by Rescue Dogs of London and Friends to raise money for charities that rehome dogs from overseas. People take part in the Rescue Dogs of London and Friends Christmas Jumper Parade on Saturday in central London. James Manning, PA Christmas sweater animal parades have become something of an annual tradition in London. People and dogs take part in the Rescue Dogs of London and Friends Christmas Jumper Parade on Saturday outside Buckingham Palace in central London. James Manning, PA There are more to come this year, including an event for corgis — the late Queen Elizabeth II's favorite breed — on Dec. 7 and the dachshund-friendly Hyde Park Sausage Walk on Dec 15. People are also reading... Most popular dog breeds in the US and the states where they're #1 Most popular dog breeds in the US and the states where they're #1 From bags of kibble in the grocery store to modern home sizes, things are getting smaller—and evidently, Americans are starting to look for furry friends that match. Small breeds like terriers and toys have largely dethroned the retrievers that once dominated the most popular breed rankings. This is a continuation of a trend that began in 2022 when the Labrador retriever lost its 31-year-long streak as #1 to the French bulldog, according to the American Kennel Club.This shift may be partially attributable to the rising costs of pet products and veterinary care since smaller dogs are more economical for tighter budgets. Moreover, as remote work and nomadic living become increasingly more common, smaller dogs may appeal to those looking for pets that require less space and are easier to transport.In fact, only two sporting dog breeds are the most popular in any American state—and neither is a Labrador retriever. The most popular dog overall represents 4% of all dogs in the country—constituting over 2.3 million out of 58 million households with dogs.Ollie used data from U.S. News & World Report to further explore which dog breeds are the most popular in which states and what factors may drive residents' preferences. otsphoto // Shutterstock Chihuahua Named after the northern Mexican state from which it originates, the Chihuahua is the smallest dog breed and one of the oldest, with a lineage that dates as far back as the ninth century. Today, the breed makes up a remarkable 4% of all dogs in the United States and is the most popular overall in 21 states. It ranks within the top five most common breeds in 42 states in total. Requiring just 200 to 250 calories per day but boasting a lifespan of 14 to 16 years, the Chihuahua offers owners low-cost longevity and is known for its adaptability and amusing personality. Canva French bulldog The French bulldog is a compact companion known for being friendly yet quiet, making it suitable for a range of lifestyles and homes. The breed has roots in the English bulldog, which was bred to a smaller size to accompany its working English owners, many of whom were artisans.As such trades closed amid the Industrial Revolution, these workers and their little bulldogs moved to France, where the breed's popularity began. The French developed a more standardized appearance which was iterated upon in the U.S. to develop the iconic bat ears. The breed has recently seen a massive increase in popularity, with AKC registrations surging by 1,000% between 2012 and 2022. Now, the French bulldog is the most popular dog in Florida, California, and Hawaii and is in the top five most common dogs in nearly half the remaining states. Branislav Nenin // Shutterstock Golden retriever With webbed paws and an affinity for water, golden retrievers are lucky pups to be the favored breed of the Midwest. They are the most popular dogs in states bordering the Great Lakes—Minnesota, Wisconsin, Michigan, Illinois, and Ohio; the entirety of the New England region minus Rhode Island; plus North Dakota, Nebraska, Colorado, and Virginia.The iconic golden breed was developed in 19th-century Scotland to retrieve both from land and water during hunts, hence its swimming-related adaptations. Golden retrievers are known for their affectionate nature and eagerness to please, making them well-suited for service and other working dog roles. PeopleImages.com - Yuri A Shih tzu The shih tzu, whose name means "lion" in Chinese, is king of the Empire State (New York) as well as Iowa, Rhode Island, and New Jersey. Roughly a quarter of New York state residents live in apartments, making the dog that averages 9 to 16 pounds perfect for compact households. Despite being known for its playfulness, the breed does not require much physical activity or space. The breed dates back over 1,000 years but was first brought to America surprisingly recently, following World War II. According to the American Kennel Club, every shih tzu alive today has direct lineage to just 14 shih tzus that were saved when the breed nearly went extinct during the Communist revolution. Canva Goldendoodle Representing the best of both worlds, the golden retriever and poodle hybrid is known for its friendly, sociable demeanor and trainability. Bred to be guide dogs in the 1960s, the hybrid is not recognized as an official breed by the AKC, so there is no breed standard. Goldendoodles can thus range from mini-sized to about 90 pounds and may have fur that is curly, straight, or somewhere in between. While not official, the family-friendly dog has left paw prints all over the country, ranking in the top five most popular dogs in 37 states. In Idaho and Utah, the goldendoodle is the most popular overall. Cavan-Images // Shutterstock Yorkshire terrier Maxing out at just 7 pounds, the Yorkshire terrier is the most popular breed among Maryland and Washington D.C. residents. This is not necessarily surprising considering the housing stock of the nation's capital is comprised mostly of apartment units, making the pint-sized pup perfect for metropolitans. The toy breed was bred to chase rats out of mines and mills in 19th-century England, arriving in North America in the 1870s and gaining official recognition by the AKC in 1885. Now, the breed is among the top five most common dogs in 26 states. The breed is a true terrier at heart, known for its feisty yet affectionate nature.'Additional research by Eliza Siegel. Story editing by Carren Jao. Additional editing by Kelly Glass. Copy editing by Tim Bruns.This story originally appeared on Ollie and was produced and distributed in partnership with Stacker Studio. Anna Averianova // Shutterstock German shepherd As loyal as they are intelligent, German shepherds are among the favored breeds for guide, military, police, and search and rescue roles. The breed, which first arrived in America in the early 20th century, also enjoys peak popularity in Alaska, Montana, Wyoming, Delaware, and Pennsylvania. Athletic in nature, the breed requires lots of exercise, making them well-suited for homes with or near lots of open land. They are also well-adapted to cold temperatures and harsher climates due to their thick double coats of fur. 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Emmanuel Addeh in Abuja The Nigerian Society of Engineers (NSE) yesterday said that there was a need for massive intervention in Nigeria’s agricultural sector to reduce the 40 per cent seasonal post-harvest losses for farm produce in-country. In a communiqué in Abuja, read by the NSE’s President, Margaret Oguntala, the umbrella body for all engineers in the country, stated that storage facilities, cold chains, and transportation networks were needed to ensure food security. The release of the communiqué marked the end of the 2024 edition of the NSE’s 57th International Engineering Conference, Exhibition and Annual General Meeting, themed: ‘Sustainable Engineering Solutions to Food Security and Climate Change’. Besides, the conference observed that about 70 per cent of Nigeria’s agriculture produce is from rural areas, where poor road network hinders transportation and distribution of produce from farms to market, causing spoilage, raising costs and reducing accessibility to consumers. Oguntala said, “With substantial post-harvest losses representing about 40 per cent of food produced in Nigeria challenging food security, conference underscored the importance of improved storage facilities, cold chains, and transportation networks. “Such infrastructure reduces food spoilage, ensures better market access, and strengthens the resilience of food supply chains.” According to her, water scarcity and inadequate irrigation systems are significant constraints to sustainable agriculture in Nigeria, stressing that out of over 84 million hectares of arable land, only about 1.6 million hectares are irrigated, leaving the rest reliant on unpredictable rainfall. The conference therefore observed the need for advanced water management solutions, including water-efficient irrigation, rainwater harvesting, and wastewater reuse. The NSE also called for the deployment of solar and wind energy to power irrigation, mechanised farming, and cold storage, reducing dependence on fossil fuels and contributing to sustainable food security. On how environmental pollution was affecting food production, the organisation said that oil spills have devastating effects on farmland and ecosystems. It explained that with engineering innovation, oil companies should adopt technology to prevent oil spills and minimise damages to agricultural land in their operational areas. The NSE also lauded President Bola Tinubu for the pronouncement to establish the National Engineering and Innovation Fund which is purposely designed to provide grants and resources to engineers and technologists working on solutions for Nigeria’s unique challenges. According to the engineers, government and relevant stakeholders, including research institutes, food processors, aggregators, exporters among others, should embrace and promote innovations and technologies that enhance agricultural productivity and reduce greenhouse gas emission. The NSE further recommended that there should be synergy among stakeholders in mitigating climate change at both individual and societal levels. “Also, relevant government agencies should implement recommendations on different climate change mitigation and adaptation strategies relevant to Nigeria as contained in Intergovernmental Panel on Climate Change (IPCC) report of Conference of Parties (COPs). “It recommends that government policies should prioritise funding for research, capacity-building, and incentives for adopting sustainable practices in agriculture through Bank of Agriculture (BOA), Bank of Industry (BOI) and other funding bodies,” the NSE added.Citius Pharmaceuticals, Inc. Reports Fiscal Full Year 2024 Financial Results and Provides Business Update