b-bye

b-bye Luigi Nicholas Mangione, the suspect in the fatal shooting of a healthcare executive in New York City, apparently was living a charmed life: the grandson of a wealthy real estate developer, valedictorian of his elite Baltimore prep school and with degrees from one of the nation's top private universities. Friends at an exclusive co-living space at the edge of touristy Waikiki in Hawaii where the 26-year-old Mangione once lived widely considered him a “great guy,” and pictures on his social media accounts show a fit, smiling, handsome young man on beaches and at parties. Now, investigators in New York and Pennsylvania are working to piece together why Mangione may have diverged from this path to make the violent and radical decision to gun down UnitedHealthcare CEO Brian Thompson in a brazen attack on a Manhattan street. The killing sparked widespread discussions about corporate greed, unfairness in the medical insurance industry and even inspired folk-hero sentiment toward his killer. But Pennsylvania Gov. Josh Shapiro sharply refuted that perception after Mangione's arrest on Monday when a customer at a McDonald's restaurant in Pennsylvania spotted Mangione eating and noticed he resembled the shooting suspect in security-camera photos released by New York police. “In some dark corners, this killer is being hailed as a hero. Hear me on this, he is no hero,” Shapiro said. “The real hero in this story is the person who called 911 at McDonald’s this morning.” Mangione comes from a prominent Maryland family. His grandfather, Nick Mangione, who died in 2008, was a successful real estate developer. One of his best-known projects was Turf Valley Resort, a sprawling luxury retreat and conference center outside Baltimore that he purchased in 1978. The Mangione family also purchased Hayfields Country Club north of Baltimore in 1986. On Monday, Baltimore County police officers blocked off an entrance to the property, which public records link to Luigi Mangione’s parents. Reporters and photographers gathered outside the entrance. The father of 10 children, Nick Mangione prepared his five sons — including Luigi Mangione’s father, Louis Mangione — to help manage the family business, according to a 2003 Washington Post report. Nick Mangione had 37 grandchildren, including Luigi, according to the grandfather's obituary. Luigi Mangione’s grandparents donated to charities through the Mangione Family Foundation, according to a statement from Loyola University commemorating Nick Mangione’s wife’s death in 2023. They donated to various causes, including Catholic organizations, colleges and the arts. One of Luigi Mangione’s cousins is Republican Maryland state legislator Nino Mangione, a spokesman for the lawmaker’s office confirmed. “Our family is shocked and devastated by Luigi’s arrest,” Mangione’s family said in a statement posted on social media by Nino Mangione. “We offer our prayers to the family of Brian Thompson and we ask people to pray for all involved.” Mangione, who was valedictorian of his elite Maryland prep school, earned undergraduate and graduate degrees in computer science in 2020 from the University of Pennsylvania, a university spokesman told The Associated Press. He learned to code in high school and helped start a club at Penn for people interested in gaming and game design, according to a 2018 story in Penn Today, a campus publication. His social media posts suggest he belonged to the fraternity Phi Kappa Psi. They also show him taking part in a 2019 program at Stanford University, and in photos with family and friends at the Jersey Shore and in Hawaii, San Diego, Puerto Rico, and other destinations. The Gilman School, from which Mangione graduated in 2016, is one of Baltimore’s elite prep schools. The children of some of the city’s wealthiest and most prominent residents, including Orioles legend Cal Ripken Jr., have attended the school. Its alumni include sportswriter Frank Deford and former Arizona Gov. Fife Symington. In his valedictory speech, Luigi Mangione described his classmates’ “incredible courage to explore the unknown and try new things.” Mangione took a software programming internship after high school at Maryland-based video game studio Firaxis, where he fixed bugs on the hit strategy game Civilization 6, according to a LinkedIn profile. Firaxis' parent company, Take-Two Interactive, said it would not comment on former employees. He more recently worked at the car-buying website TrueCar, but has not worked there since 2023, the head of the Santa Monica, California-based company confirmed to the AP. From January to June 2022, Mangione lived at Surfbreak, a “co-living” space at the edge of touristy Waikiki in Honolulu. Like other residents of the shared penthouse catering to remote workers, Mangione underwent a background check, said Josiah Ryan, a spokesperson for owner and founder R.J. Martin. “Luigi was just widely considered to be a great guy. There were no complaints,” Ryan said. “There was no sign that might point to these alleged crimes they’re saying he committed.” At Surfbreak, Martin learned Mangione had severe back pain from childhood that interfered with many aspects of his life, including surfing, Ryan said. “He went surfing with R.J. once but it didn’t work out because of his back,” Ryan said, but noted that Mangione and Martin often went together to a rock-climbing gym. Mangione left Surfbreak to get surgery on the mainland, Ryan said, then later returned to Honolulu and rented an apartment. An image posted to a social media account linked to Mangione showed what appeared to be an X-ray of a metal rod and multiple screws inserted into someone's lower spine. Martin stopped hearing from Mangione six months to a year ago. An X account linked to Mangione includes recent posts about the negative impact of smartphones on children; healthy eating and exercise habits; psychological theories; and a quote from Indian philosopher Jiddu Krishnamurti about the dangers of becoming “well-adjusted to a profoundly sick society.” Mangione likely was motivated by his anger at what he called “parasitic” health insurance companies and a disdain for corporate greed, according to a law enforcement bulletin obtained by AP. He wrote that the U.S. has the most expensive healthcare system in the world and that the profits of major corporations continue to rise while “our life expectancy” does not, according to the bulletin, based on a review of the suspect’s handwritten notes and social media posts. He appeared to view the targeted killing of the UnitedHealthcare CEO as a symbolic takedown, asserting in his note that he is the “first to face it with such brutal honesty,” the bulletin said. Mangione called “Unabomber” Ted Kaczynski a “political revolutionary” and may have found inspiration from the man who carried out a series of bombings while railing against modern society and technology, the document said. Associated Press reporters Lea Skene in Baltimore; Jennifer Sinco Kelleher in Honolulu; Maryclaire Dale in Philadelphia; John Seewer in Toledo, Ohio; and Michael Kunzelman in Washington, D.C., contributed to this report.

WASHINGTON — President-elect Donald Trump called his meeting with Justin Trudeau productive and says the prime minister made a commitment to work with the United States to end the drug crisis amid the threat of stiff tariffs. “We discussed many important topics that will require both Countries to work together to address, like the Fentanyl and Drug Crisis that has decimated so many lives as a result of Illegal Immigration, Fair Trade Deals that do not jeopardize American Workers, and the massive Trade Deficit the U.S. has with Canada,” Trump said in a post on Truth Social Saturday. Trudeau flew to Florida Friday evening to attend a dinner at Mar-a-Lago, where Trump’s transition team is based. The in-person meeting came at the end of a rocky week in which Trump threatened to impose stiff tariffs on all imports from Canada and Mexico, unless the two countries stop illegal border crossings and prevent illicit drugs from entering the United States. Trump said he and Trudeau discussed the drug crisis and the president-elect made it “very clear that the United States will no longer sit idly by as our Citizens become victims” of the drug epidemic, which he attributed to cartels and fentanyl coming from China. “Prime Minister Trudeau has made a commitment to work with us to end this terrible devastation of U.S. Families,” Trump posted. Trump said the pair also discussed illegal immigration, as well as trade, energy and the Arctic. Trump’s post did not directly mention tariffs and it’s unclear whether the prime minister’s visit has alleviated his concerns about the border. Trudeau, in West Palm Beach Saturday morning, answered a reporter’s question about the dinner, calling it “an excellent conversation.” A statement from the Prime Minister’s Office said the two leaders “shared a productive wide-ranging discussion over dinner.” It was centred on collaboration and strengthening the bilateral relationship. “As Canada’s closest friend and ally, the United States is our key partner, and we are committed to working together in the interests of Canadians and Americans,” the statement said. Trudeau had a notably rocky relationship with the Republican leader during the first Trump administration. However, the prime minister was the first G7 leader to visit Trump since the Nov. 5 election. Trump’s tariff threats are critical for Canada. More than 77 per cent of Canadian exports go to the United States. Trudeau said earlier Friday that he would resolve the issue by talking with Trump.The latest environmental, social and governance (ESG) information can be found at avistacorp.com . SPOKANE, Wash., Dec. 23, 2024 (GLOBE NEWSWIRE) -- Today, Avista (NYSE: AVA) published its latest Corporate Responsibility report and other environmental, social and governance (ESG) information on its corporate website, avistacorp.com . The content reports on Avista’s operations and includes commitments in four areas: environment, people, customers and communities, and ethical governance. The latest report includes progress updates regarding Avista’s aspirational goals for Clean Energy, for workplace Equity, Inclusion, and Diversity, for Supplier Diversity, and the publication of Avista’s current Equal Employment Opportunity (EEO) 2023 Employer Information Report EEO-1 Consolidated Report. The website also provides links to Avista’s continued reporting on a series of key ESG reporting frameworks and industry specific ESG disclosures and metrics that include new reports adhering to the Task Force on Climate-Related Financial Disclosures (TCFD), the Sustainability Accounting Standards Board (SASB), the Edison Electric Institute (EEI) and the American Gas Association (AGA) ESG and sustainability reporting frameworks. “Our mission is to enable vibrant communities through safe, responsible, and affordable energy. Avista’s annual Corporate Responsibility Report is an opportunity for us to provide information and concrete examples that demonstrate our company’s commitments to our stakeholders in support of this mission. From ensuring robust energy supply and delivery systems, partnering in the shared clean energy economy, inspiring engaged and thriving employees, to committing to financial strength, these are just some of the ways we are delivering upon our mission,” said Avista CEO Dennis Vermillion. Avista’s Corporate Responsibility report and ESG disclosures can be found here and at avistacorp.com. About Avista Corp. Avista Corp. is an energy company involved in the production, transmission, and distribution of energy as well as other energy-related businesses. Avista Utilities is our operating division that provides electric service to 418,000 customers and natural gas to 382,000 customers. Our service territory covers 30,000 square miles in eastern Washington, northern Idaho, and parts of southern and eastern Oregon, with a population of 1.7 million. AERC is an Avista subsidiary that, through its subsidiary AEL&P, provides retail electric service to 17,000 customers in the city and borough of Juneau, Alaska. Our stock is traded under the ticker symbol “AVA”. For more information about Avista, please visit www.avistacorp.com. Avista Corp. and the Avista Corp. logo are trademarks of Avista Corporation. To unsubscribe from Avista’s news release distribution, send reply message to dalila.sheehan@avistacorp.com. SOURCE: Avista Corporation Contact: Media: Lena Funston (509) 495-8090 lena.funston@avistacorp.com Investors: Stacey Wenz (509) 495-2046 stacey.wenz@avistacorp.com Avista 24/7 Media Access (509) 495-4174

Coastal Financial Corporation Announces Proposed Public Offering of Common Stock

Canadian news publishers sue OpenAI over alleged copyright infringementSan Diego State edges No. 6 Houston 73-70 in overtime to finish 3rd in Players Era tournament(The Center Square) – Bob Casey Jr. is finally ready to say goodbye. Seventeen days after the polls closed, the two-term Democratic senator called Republican challenger Dave McCormick to congratulate him on his win. “As the first count of ballots is completed, Pennsylvanians can move forward with the knowledge that their voices were heard, whether their vote was the first to be counted or the last,” he said in a video posted on X . The concession comes after 16 of 67 counties finished recounting ballots cast, with results showing Casey falling even further behind. Of 702,000 ballots tallied again, McCormick, who declared victory three days after the election, increased his lead by seven votes. During my time in office, I have been guided by an inscription on the Finance Building in Harrisburg: “All public service is a trust, given in faith and accepted in honor.” Thank you for your trust in me for all these years, Pennsylvania. It has been the honor of my lifetime. pic.twitter.com/RSXEFwdge8 The close margin – less than 17,000 ballots or 0.2% – triggered an automatic recount last week, to which Casey could have objected. Counties have until Tuesday to finish the job. Elizabeth Gregory, spokeswoman for McCormick, said in a release “there’s only five more days until the obvious happens.” “Another day closer to this waste of time and money being over,” she said. “We all know how this will end. We’ll be there in five days.” The campaign had maintained there were not enough votes left in the state to overcome the gap . Chief strategist Mark Harris said Casey’s decision to opt for the recount, estimated to cost $1 million, won’t change things. The Associated Press, reached the same conclusion on Nov. 7 when declaring the former hedge fund CEO turned Republican nominee the winner . The flip padded the Republican majority in the U.S. Senate to 53-47 and ended the Casey family’s six-decade presence in state and national political office. “During my time in office, I have been guided by an inscription on the Finance Building in Harrisburg: ‘All public service is a trust, given in faith and accepted in honor,’” Casey said. “Thank you for your trust in me for all these years, Pennsylvania. It has been the honor of my lifetime.”

NHL insider: Jim Montgomery ‘had one eye on the Blues’ after Bruins firingHow wine jargon leaves Brits in terroir: More than 50% of wine lovers are baffled by its terminology while a third are left embarrassed when asked to describe a type By DAILY MAIL REPORTER Published: 17:35 EST, 21 November 2024 | Updated: 17:55 EST, 21 November 2024 e-mail 5 View comments We may be changing from beer fans to wine buffs, but most of us still don't know our terroir from our tannins. More than half of so-called wine lovers are baffled by its terminology. According to a survey, 48 per cent have been caught out at a dinner party for using jargon they did not properly understand. Meanwhile, 34 per cent were left embarrassed when asked to describe a wine they brought to a dinner party, and 36 per cent would not feel confident explaining what a blended wine is. The most confusing term for those intimidated by the grapes of wrath, according to 60 per cent of those polled, is 'terroir', with one in 20 thinking it means 'terribly good'. In fact, it refers to the environmental conditions that affect the taste and quality of a wine. Other wine words that leave Brits scratching their heads include 'caudalie' (44 per cent) – the measurement of how long the taste stays on the palate, and 'oenology' (41 per cent) – the science of wine and wine-making. The terms 'maceration' (41 per cent) – the process of soaking wine skins to extract colour and tannins, and 'cuvee' (41 per cent) – a wine made with a blend of different varieties of grapes, were also among the list of the 20 terms many don't really understand. More than half of so-called wine lovers are baffled by its terminology according to a new survey 48 per cent of wine drinkers have been caught out at a dinner party for using jargon they did not properly understand The most confusing term for those intimidated by the grapes of wrath, according to 60 per cent of those polled, is 'terroir' Despite the challenges, more than two-thirds (84 per cent) would like to increase their wine knowledge, the motivations including, feeling more confident when discussing wine (50 per cent) improving their ability to pair wine with food (42 per cent), navigating wine lists more comfortably (29 per cent), and even appearing more intelligent (22 per cent). One in five (19 per cent) would like to impress friends and family with their wine knowledge, so much so that more than half (52 per cent) enjoy receiving advice on wines when shopping in stores. A significant 69 per cent love trying new wines, according to the research by new wine range CTZN. Oliver Hoey from Aussie wine brand CTZN, which commissioned the survey of 2,000 Brits, said: 'Brits love wine, but want the confidence to talk about it more in social settings. 'We are giving wine lovers the tools they need to feel confident and informed, with SOM, our AI-powered virtual sommelier, providing an engaging and interactive way to deepen the understanding of the wine in their glass.' Share or comment on this article: How wine jargon leaves Brits in terroir: More than 50% of wine lovers are baffled by its terminology while a third are left embarrassed when asked to describe a type e-mail Add comment

Special counsel moves to dismiss election interference case against Donald TrumpInside the Gaetz ethics report, a trove of new details alleging payments for sex and drug use

Rays will play 13 of first 16 games at home and 47 of 59, then have 69 of last 103 on roadThe decision by special counsel Jack Smith, who had fiercely sought to hold Mr Trump criminally accountable for his efforts to subvert the 2020 election, represented the end of the federal effort against the former president following his election victory this month despite the election-related cases and multiple other unrelated criminal charges against him. The move, announced in court papers, marks the end of the Justice Department’s landmark effort to hold Mr Trump accountable for what prosecutors called a criminal conspiracy to cling to power in the run-up to his supporters’ attack on the US Capitol on January 6 2021. In court papers, prosecutors said the Justice Department’s position “is that the Constitution requires that this case be dismissed before the defendant is inaugurated”. Mr Smith’s team emphasised that the move to abandon the prosecutions, in federal courts in Washington and Florida, was not a reflection of their view on the merits of the cases but rather a reflection of their commitment to longstanding department policy. “That prohibition is categorical and does not turn on the gravity of the crimes charged, the strength of the Government’s proof, or the merits of the prosecution, which the Government stands fully behind,” the prosecutors wrote in Monday’s court filing in the election interference case. The decision was expected after Mr Smith’s team began assessing how to wind down both the 2020 election interference case and the separate classified documents case in the wake of Mr Trump’s victory over Vice President Kamala Harris. The Justice Department believes Trump can no longer be tried in accordance with longstanding policy that says sitting presidents cannot be prosecuted. Mr Trump has cast both cases as politically motivated and has vowed to fire Mr Smith as soon as he takes office in January. The 2020 election case brought last year was once seen as one of the most serious legal threats facing the Republican as he vied to reclaim the White House. However, it quickly stalled amid legal fighting over Mr Trump’s sweeping claims of immunity from prosecution for acts he took while in the White House. The US Supreme Court in July ruled for the first time that former presidents have broad immunity from prosecution, and sent the case back to US District Judge Tanya Chutkan to determine which allegations in the indictment, if any, could proceed to trial. The case was just beginning to pick up steam again in the trial court in the weeks leading up to this year’s election. Mr Smith’s team filed a lengthy brief in October laying out new evidence they planned to use against him at trial, accusing him of “resorting to crimes” in an increasingly desperate effort to overturn the will over voters after he lost to President Joe Biden.

Dazzling artistry, mechanical creativityPLEASANTON, Calif. , Dec. 23, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today it had secured a permanent injunction in the U.S. District Court for the District of Delaware against the GeoMx products sold by Bruker Corporation (Nasdaq: BRKR), which acquired the product line from NanoString Technologies. To minimize the risk of disruption to ongoing research, 10x Genomics requested a carve-out for GeoMx users who installed an instrument prior to the trial in November 2023 . The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc.

Danielle Smith congratulates the loser of the Lethbridge-West by-election

PLEASANTON, Calif. , Dec. 23, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today it had secured a permanent injunction in the U.S. District Court for the District of Delaware against the GeoMx products sold by Bruker Corporation (Nasdaq: BRKR), which acquired the product line from NanoString Technologies. To minimize the risk of disruption to ongoing research, 10x Genomics requested a carve-out for GeoMx users who installed an instrument prior to the trial in November 2023 . The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc.Anderson .Paak and Mariah Carey may not share a lot on the surface (outside of being musicians), but they've both gone through some heartbreak. In early 2024, the Silk Sonic bandmate painfully decided to move on from his wife of 13 years, Jae Lin. Making matters worse is that they share two children, so you can only imagine the stress. Then, for Mariah, she's been trying to move on from losing her mother Patricia and her sister Alison on the same day. However, beyond just the grieving, a close friend of her sister made some pretty bombshell claims that Mariah knew about her sibling's declining health and did nothing to help. We can only imagine how hard it's been at times for both of them, so we continue to send our best to them. So, why are we comparing Anderson .Paak and Mariah Carey anyway? Well, it seems that they could be possibly dating, or at least getting there, according to TMZ . Paparazzi caught the two R&B superstars walking into a bougie chain restaurant known as Catch Steak, with this one being in Aspen, Colorado. Read More: Kendrick Lamar Named Billboard's Greatest Pop Star Of 2024 Sparking Social Media Uproar If you want to see the photographic evidence of their "dinner date," check out the "[Via]" link below. If you do take a look you'll see .Paak opening the door for Mariah while also placing his hand on her back. Moreover, there's a closer shot of them holding hands and they were all smiles throughout! However, where the sensual tension dissipates is that sources at the restaurant say they left separately. As it stands, they are not dating but instead working on music together. During the summer, .Paak posted some videos documenting their Electric Lady recording studio in New York City. So, it seems they were just taking some time away from work to grab a bite and kick back. However, we are holding out hope for these two potential lovebirds, especially with the holiday spirit in the air! Also, that music is hopefully coming soon as well! A possible "All I Want For Christmas" Silk Sonic remix?! Yes please! Read More: Kim Kardashian Covers Eartha Kitt's Classic "Santa Baby" Just In Time For The Holiday

Jets' Aaron Rodgers shares thoughts on drones flying over New Jersey: 'What the hell is that?'Breaking News Don't miss out on the headlines from Breaking News. Followed categories will be added to My News. After a far-right pro-Russia candidate secured a surprise lead in Romania's presidential election Monday, the eastern European NATO member is bracing for a high-stakes parliamentary vote on Sunday, amid fears it could bring about a strategic shift in the country. Calin Georgescu was in pole position with almost 23 percent after the first round of voting, a political earthquake in the country of 19 million people that has so far resisted nationalist appeals that have gained traction in Hungary and Slovakia. His victory ahead of centre-right mayor Elena Lasconi -- who scored 19.18 percent -- ended the hopes of Prime Minister Marcel Ciolacu to compete for the presidency in the December runoff. After coming third at 19.15, Ciolacu said his Social Democratic Party (PSD) won't challenge the narrow result, and announced his resignation as party leader. Experts say the far right's surprise success could affect the parliamentary elections later this week, and even influence the chances of forming a future government. - 'Existential battle' - In the runoff ballot on December 8, Lasconi will face Georgescu, a NATO critic who in the past expressed his admiration for Russian President Vladimir Putin. Georgescu's popularity surged ahead of the vote with a viral TikTok campaign calling for an end to aid for Ukraine, which shares a 650-kilometre (400-mile) border with Romania. In a first reaction on his YouTube channel, the 62-year-old independent candidate insisted "there is no East or West", stressing that neutrality was "absolutely necessary". "I am not an extremist, I am not a fascist -- I am a Romanian who loves his country," he said in reference to media reports that "tried to portray" him in a wrongful way. For his rival Lasconi, the upcoming runoff represents "an existential battle", "a historic confrontation" between those who wish to "preserve Romania's young democracy" and those who want to "return to the Russian sphere of influence". "We must not allow anger to throw us back into the past," she said to thunderous applause from her supporters, vowing to stand up for Europe and NATO. The political earthquake comes amid soaring inflation and mounting fears of Romania being potentially dragged into Russia's war in neighbouring Ukraine, as the country has emerged as a key player on the alliance's eastern flank. - 'Serious and patriotic' - In Sunday's vote, another far-right contender, AUR party leader George Simion, secured nearly 14 percent. Already pounding the campaign trail for this week's parliamentary elections, Simion said Romania now has "the chance to have a sovereign government and a sovereign president". Overall, the far right won more than a third of all votes in Sunday's presidential ballot. "The far right is by far the big winner of this election," political scientist Cristian Pirvulescu told AFP, predicting a possible "contagion effect" in the parliamentary vote. Extremist forces and Lasconi's centre-right party now have "wind in their sails", sociologist Gelu Duminica said, though "it remains to be seen if they know how to capitalise" on it. The PSD, which has shaped the country's politics for more than three decades, has never before been eliminated in the first round of a presidential election. The National Liberal Party (PNL) party, with whom the PSD currently governs, also suffered a defeat. While many expressed their disbelief over the poll in the streets of the capital Bucharest, others were enthused. Maria Chis, 70, said she was surprised by Georgescu's lead in the first round but had been impressed after watching his TikTok videos. "He seems a man of integrity, serious and patriotic. He inspires seriousness. I think only someone like him can bring change," said the pensioner, who was planning to vote for him in the second round. Alex Tudose, the owner of a construction company, was gloomy. "There is sorrow, disappointment, that after so many years in Euro-Atlantic structures we voted for a pro-Russian by over 20 percent," the 42-year-old said. "There is clearly a strong fragmentation both in society and in the political class, and I think we saw that yesterday," he said. ani-anb-kym/sbk Originally published as Romania braces for parliamentary vote after far right's poll upset More related stories National Cops probe woman’s mysterious death New details have emerged as a man faced court on a slew of violent charges just days after the body of a woman was discovered. Read more Breaking News 40k homebuyers to get major boost Eligible first-homebuyers are closer to being able to co-purchase a home with the government after Labor finally passed its Help to Buy legislation through the Senate. Read more

Telangana: Surekha suspects RS Praveen’s hand in food poisoning cases in GurukulsSaturday, November 30, 2024 Cuba continues to captivate Uruguayan tourists with its vibrant culture, stunning landscapes, and warm hospitality. As a destination rich in geography, history, and traditions, Cuba remains a top choice for travelers seeking an immersive experience. With recent advancements in travel processes and connectivity, visiting this tropical paradise has never been easier. Cuba’s tourism industry is thriving, welcoming over 2.4 million international visitors in 2023. While Canadian tourists made up the majority, the surge reflects a growing global interest, including a rising number of travelers from Uruguay. For these tourists, Cuba offers an unmatched blend of pristine beaches, cultural richness, and culinary delights, making it a top-tier destination. Varadero Beach, recently named the second-best beach in the world, remains a crown jewel for visitors. Equally alluring is Havana, celebrated as the “Latin American capital of cocktails,” where travelers can enjoy Cuba’s famed rum and indulge in its rich musical heritage as the birthplace of son music. Beyond leisure, Cuba also shines as a hub for international events and is rapidly gaining recognition in the health tourism sector. Getting to Cuba from Uruguay is now more convenient than ever. With regular flights from airlines such as Latam, Copa, Avianca, and Bolivia’s Boa, travel to the island is seamless. Excitingly, an exploratory mission by Cubana de Aviación scheduled for December 6 aims to solidify direct flights between South America and Cuba, further improving accessibility for Uruguayan tourists. In a significant step to boost tourism, Cuba recently introduced an electronic visa system, simplifying the travel process for Uruguayans. The e-visa eliminates traditional barriers, making it easier than ever to plan a trip. This innovation is expected to encourage more Uruguayan travelers to experience Cuba’s charm. The shared cultural ties between Uruguay and Cuba add another layer of appeal for Uruguayan tourists. These enhanced travel processes and connectivity improvements underscore Cuba’s commitment to fostering stronger bonds with Uruguay, ensuring an unforgettable journey for those exploring its vibrant destinations. By simplifying travel and boosting connectivity, Cuba has positioned itself as a must-visit destination for Uruguayans, offering easy access to an array of extraordinary experiences. Cuba is a vibrant blend of history, culture, and natural beauty. Its cities are alive with music, color, and a unique charm that promises unforgettable experiences. Here’s your guide to the must-visit cities of Cuba: Havana is a city like no other, where old-world charm meets contemporary vibrancy. Top Attractions : Local Tips : Known for its turquoise waters and powdery sands, Varadero is the ultimate tropical getaway. Top Attractions : Local Tips : Step back in time in Trinidad, where cobblestone streets and pastel-colored buildings tell stories of the past. Top Attractions : Local Tips : Known as the cradle of the Cuban Revolution, Santiago is a hub of Afro-Cuban culture and music. Top Attractions : Local Tips : Cienfuegos boasts French-inspired architecture and a serene coastal atmosphere. Top Attractions : Local Tips : Famous for its labyrinthine streets and artistic vibe, Camagüey offers a quieter side of Cuba. Top Attractions : Local Tips : Santa Clara is the final resting place of Che Guevara and a must-visit for history buffs. Top Attractions : Local Tips : Home to Cuba’s lush tobacco fields and stunning landscapes, Pinar del Río is ideal for nature lovers. Top Attractions : Local Tips : Cuba is a destination that offers something for everyone, from history and culture to relaxation and adventure. Pack your bags and get ready to explore this enchanting island!