mnl777 login app philippines download
MAPS IMPORTANT DEADLINE: ROSEN, SKILLED INVESTOR COUNSEL, Encourages WM Technology, Inc. ...Bihar Guv CM condole Manmohan Singh's death
SAN FRANCISCO , Dec. 26, 2024 /PRNewswire/ -- AusperBio Therapeutics, Inc . and Ausper Biopharma Co., Ltd . (collectively AusperBio ), a privately held clinical-stage biotechnology company dedicated to advancing targeted oligonucleotide therapies to achieve a functional cure for chronic hepatitis B ( CHB ), today announced the successful completion of a USD 73 million Series B financing. The round was led by HanKang Capital , with participation from Sherpa Capital , CDH Investments , and a strategic investor, as well as continued participation from existing investors Qiming Venture Partners , InnoPinnacle Fund , and YuanBio Venture Capital . This financing followed the company's Series A round completed in July this year, demonstrating continued investor confidence in its proprietary platform and strategic direction. The proceeds will fund the continued Phase 2 development of AHB-137 , AusperBio's lead investigational therapy, supporting both clinical studies in China and global trials, as well as the development of commercial-scale manufacturing processes. The funding will also facilitate the expansion of the company's therapeutic pipeline and operational capabilities to drive sustained growth. Dr. Guofeng Cheng , co-founder and CEO of AusperBio, stated, " We are honored by our investors' confidence and support. This milestone financing recognizes our scientific and clinical accomplishments to date and enables us to accelerate our clinical programs and move closer to delivering a functional cure for CHB patients in need." Dr. Chris Yang , co-founder and CSO, added, "AHB-137 continues to attract attention from the scientific and clinical communities, particularly after the late-breaking oral presentation at the recent AASLD conference. The promising clinical data further validates our Med-OligoTM platform, strengthening our development of groundbreaking targeted oligonucleotide therapies for CHB and other serious chronic diseases." AusperBio is committed to delivering patient-centered innovations, aiming to alleviate the global health burden of CHB and transform treatment paradigms for this serious chronic disease. About AHB-137 AHB-137, a novel unconjugated antisense oligonucleotide ( ASO ) developed within AusperBio's proprietary Med-OligoTM ASO technology platform, was designed to treat chronic hepatitis B for a functional cure. Its compelling preclinical and Phase 1 clinical data were highlighted at the 2023 EASL conference and the 2024 EASL conference, respectively. Interim Phase 2a data was presented in a late-breaking oral session at the 2024 AASLD. This novel dual-mechanism ASO has completed its global Phase 1b trial and is now undergoing multiple Phase 2 trials in China . With its global development strategy, AHB-137 is advancing rapidly toward the goal of an HBV cure. About AusperBio. AusperBio is a clinical-stage biopharmaceutical company with operations in the USA and China , dedicated to advancing oligonucleotide and targeted delivery technologies for transformative therapies, with an initial focus on curing chronic hepatitis B infection. The company has developed a proprietary Med-OligoTM ASO platform which has been shown to substantially enhance the current ASO therapeutics, through novel insights into ASO design. Combining with efficient targeted delivery conjugation technologies, the modular Med-OligoTM Platform empowers ASO therapeutics to treat a broad range of diseases, including viral infections, metabolic conditions, genetic disorders, and immune diseases. For further information, please contact: Media Contact Email: info@ausperbio.com Investor Relations Contact: Tel: 650-888-1756 (US) Email: growth@ausperbio.com View original content to download multimedia: https://www.prnewswire.com/news-releases/ausperbio-secures-73-million-in-series-b-financing-to-advance-functional-cure-for-chronic-hepatitis-b-302339451.html SOURCE AusperBio Therapeutics Inc.
‘An appalling tragedy’: Tributes paid to Leinster House usher killed while cycling in CastleknockIran said on Sunday that it would hold nuclear talks in the coming days with the three European countries that initiated a censure resolution against it adopted by the UN's atomic watchdog. Foreign ministry spokesman Esmaeil Baghaei said the meeting of the deputy foreign ministers of Iran, France, Germany and the United Kingdom would take place on Friday, without specifying a venue. "A range of regional and international issues and topics, including the issues of Palestine and Lebanon, as well as the nuclear issue, will be discussed," the spokesman said in a foreign ministry statement. Baghaei described the upcoming meeting as a continuation of talks held with the countries in September on the sidelines of the annual session of the United Nations General Assembly in New York. On Thursday, the 35-nation board of governors of the UN's International Atomic Energy Agency (IAEA) adopted a resolution denouncing Iran for what it called a lack of cooperation. The move came as tensions ran high over Iran's atomic programme, which critics fear is aimed at developing a nuclear weapon -- something Tehran has repeatedly denied. In response to the resolution, Iran announced it was launching a "series of new and advanced centrifuges". Centrifuges enrich uranium transformed into gas by rotating it at very high speed, increasing the proportion of fissile isotope material (U-235). "We will substantially increase the enrichment capacity with the utilisation of different types of advanced machines," Behrouz Kamalvandi, Iran's atomic energy organisation spokesman, told state TV. The country, however, also said it planned to continue its "technical and safeguards cooperation with the IAEA". During a recent visit to Tehran by IAEA head Rafael Grossi, Iran agreed to the agency's demand to cap its sensitive stock of near weapons-grade uranium enriched up to 60 percent purity. Iranian President Masoud Pezeshkian, in power since July and a supporter of dialogue with Western countries, has said he wants to remove "doubts and ambiguities" about his country's nuclear programme. In 2015, Iran and world powers reached an agreement that saw the easing of international sanctions on Tehran in exchange for curbs on its nuclear programme. But the United States unilaterally withdrew from the accord in 2018 under then-president Donald Trump and reimposed biting economic sanctions, which prompted Iran to begin rolling back on its own commitments. On Sunday afternoon, the United Kingdom confirmed the upcoming meeting between Iran and the three European countries. "We remain committed to taking every diplomatic step to prevent Iran from developing nuclear weapons, including through snapback if necessary," London's Foreign Office said. The 2015 deal contains a "snapback" mechanism that can be triggered in case of "significant non-performance" of commitments by Iran, allowing many sanctions to be reimposed. Ali Vaez, an Iran expert with the International Crisis Group think tank, told AFP that Friday's meeting was set to happen earlier, but "those plans were derailed as a result of Iran-Israel tensions" over the Gaza war. Though the parties will be meeting "without knowing what the incoming Trump administration wants to do", Vaez said that "after a lose-lose cycle of mutual escalation, now both sides are back to realising that engagement might be the least costly option." Tehran has since 2021 decreased its cooperation with the IAEA by deactivating surveillance devices monitoring the nuclear programme and barring UN inspectors. At the same time, it has increased its stockpiles of enriched uranium and the level of enrichment to 60 percent. That level is close, according to the IAEA, to the 90 percent-plus threshold required for a nuclear warhead, and substantially higher than the 3.67 percent limit it agreed to in 2015. pdm/smw/amiBeacon Healthcare Systems Expands Leadership Team with Addition of Ayman Mohamed as Chief Technology Officer
WASHINGTON — Donald Trump said he can't guarantee that his promised tariffs on key U.S. foreign trade partners won't raise prices for American consumers and he suggested once more that some political rivals and federal officials who pursued legal cases against him should be imprisoned. The president-elect, in a wide-ranging interview with NBC's “Meet the Press” that aired Sunday, also touched on monetary policy, immigration, abortion and health care, and U.S. involvement in Ukraine, Israel and elsewhere. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.
Women will for the first time make up a majority of state legislators in Colorado and New Mexico next year, but at least 13 states saw losses in female representation after the November election, according to a count released Thursday by the Rutgers Center for American Women and Politics. While women will fill a record number of state legislative seats in 2025, the overall uptick will be slight, filling just over third of legislative seats. Races in some states are still being called. "We certainly would like to see a faster rate of change and more significant increases in each election cycle to get us to a place where parity in state legislatures is less novel and more normal," said Kelly Dittmar, director of research at the CAWP, which is a unit of the Eagleton Institute of Politics at Rutgers University. As of Wednesday, at least 2,450 women will serve in state legislatures, representing 33.2% of the seats nationwide. The previous record was set in 2024 with 2,431 women, according to the CAWP. People are also reading... Mitchell Gold + Bob Williams making furniture in Alexander County again Statesville survives test from Franklin in high school football playoff opener Iredell County bridge to close for $1.2 replacement project Lake Norman residents voice concerns with Marshall Steam Station changes Believers bought airplane for dead preacher thinking he’d rise from grave to fly in it Basketball transfer Patterson back home at West Iredell to 'bring in some wins' MerMade: Workspace opens in Statesville, caters to artists, crafters With supermajority in NC House gone, Iredell's Republican lawmakers talk changes, challenges Catawba native Christina Eagle appears on season 26 of 'The Voice' Statesville embraces underdog role in rematch with defending champ Hickory Iredell County woman wins first $150,000 top prize in new game Mooresville puts up 70 points, routs Alexander Central in high school football playoffs West Iredell starts season strong with win over Bunker Hill Statesville sweeps varsity doubleheader with South Iredell; Shehan reaches 1,000 points in Lake Norman win Statesville native's book offers clues to 5 hidden treasures The number of Republican women, at least 851, will break the previous record of 815 state lawmakers set in 2024. "But still, Republican women are very underrepresented compared to Democratic women," Debbie Walsh, director of the CAWP, said. From left, House Maj. Whip Reena Szczepanski, D-Santa Fe, Rep. D. Wonda Johnson, D-Church Rock and Rep. Cristina Parajon, D-Albuquerque, talk July 18 before the start of a special session, in Santa Fe, N.M. States with gains By the most recent count, 19 states will have increased the number of women in their state legislatures, according to the CAWP. The most notable increases were in New Mexico and Colorado, where women will for the first time make up a majority of lawmakers. In New Mexico, voters sent an 11 additional women to the chambers. Colorado previously attained gender parity in 2023 and is set to tip over to a slight female majority in the upcoming year. The states follow Nevada, which was the first in the country to see a female majority in the legislature following elections in 2018. Next year, women will make up almost 62% of state lawmakers in Nevada, far exceeding parity. Women in California's Senate will make up the chamber's majority for the first time in 2025 as well. Women also made notable gains in South Dakota, increasing its number by at least nine. Four of South Carolina's Sister Senators, from left, Sen. Margie Bright Matthews, D-Walterboro, Sen. Mia McLeod, I-Columbia, Sen. Katrina Shealy, R-Lexington, and Sen. Penry Gustafson, R-Camden, stand in front of the Senate on June 26 with their John F. Kennedy Profile in Courage award in Columbia, S.C. States that lost At least thirteen states emerged from the election with fewer female lawmakers than before, with the most significant loss occurring in South Carolina. This year, the only three Republican women in the South Carolina Senate lost their primaries after they stopped a total abortion ban from passing. Next year, only two women, who are Democrats, will be in the 46-member Senate. No other state in the country will have fewer women in its upper chamber, according to the CAWP. Women make up 55% of the state's registered voters. Half the members in the GOP dominated state were elected in 2012 or before, so it will likely be the 2040s before any Republican woman elected in the future can rise to leadership or a committee chairmanship in the chamber, which doles out leadership positions based on seniority. A net loss of five women in the legislature means they will make up only about 13% of South Carolina's lawmakers, making the state the second lowest in the country for female representation. Only West Virginia has a smaller proportion of women in the legislature. West Virginia stands to lose one more women from its legislative ranks, furthering its representation problem in the legislature where women will make up just 11% of lawmakers. Why it matters Many women, lawmakers and experts say that women's voices are needed in discussions on policy, especially at a time when state government is at its most powerful in decades. Walsh, director of the CAWP, said the new changes expected from the Trump administration will turn even more policy and regulation to the states. The experiences and perspectives women offer will be increasingly needed, she said, especially on topics related to reproductive rights, healthcare, education and childcare. "The states may have to pick up where the federal government may, in fact, be walking away," Walsh said. "And so who serves in those institutions is more important now than ever." 20 political cartoons draw out Donald Trump's win November 7, 2024: Trump Victory Stay up-to-date on the latest in local and national government and political topics with our newsletter.