bookmaker board
In conclusion, Neymar's unwavering determination to join Barcelona highlights the deep emotional connection and desire he holds for his former club. As the transfer saga continues to unfold, the issue of registration looms large as a crucial factor that could determine the outcome of the deal. Only time will tell whether Neymar's dream of returning to Camp Nou will become a reality, but one thing is clear – his passion and commitment to the club remain as strong as ever.
Cadillac has “agreement in principle” to join F1 as 11th team in 2026 | Formula 1On the demand side, the global economy continues to show signs of resilience, with strong demand for oil from major consuming nations. Rapid industrialization and urbanization in emerging economies, coupled with robust economic growth in developed countries, have led to an increase in oil consumption. As a result, the demand for oil remains robust, providing support for higher prices.
By Jody Godoy (Reuters) - Andrew Ferguson, President-elect Donald Trump's pick to chair the U.S. Federal Trade Commission, has expressed the desire to go after Big Tech companies while taking a hands-off approach to regulating artificial intelligence. Ferguson's views on social media, data privacy, AI and the need to boost American competitiveness are likely to affect the regulator's approach to companies including Meta Platforms, Microsoft and Alphabet's Google. Here are some of the views Ferguson has expressed in statements during his term as an FTC commissioner which began in April and ends in 2030. ARTIFICIAL INTELLIGENCE The "pro-regulation side of the AI debate" is "the wrong one," Ferguson said. "A knee-jerk regulatory response will only squelch innovation, further entrench Big Tech incumbents, and ensure that AI innovators move to jurisdictions friendlier to them — but perhaps hostile to the United States," he said in a September statement on the FTC's report on social media. The report called for comprehensive legislation to protect users' data and prevent AI from perpetuating discrimination. ONLINE PRIVACY Ferguson has described the vast collection, aggregation and indefinite storage of data on social media and internet users in the U.S. as an "online privacy crisis" that regulators should focus on. However, he has warned against regulating how such information is used to target advertising. "If regulators and lawmakers attempt to ban or seriously curtail targeted advertising, they will be undoing the balance of the online economy," he said. CONTENT MODERATION POLICIES Ferguson has criticized social media platforms for instituting "Orwellian policies banning nebulous categories of content like 'misinformation,' 'disinformation,' and 'hate speech.'" The FTC could take action against social media platforms if their terms of service misled users about content moderation policies. With more transparent policies, users could decide if they want to stay on the platforms, Ferguson said in December. "But the choice would be real only if there are suitable free-speech-respecting substitutes to the censorious platforms," Ferguson said, praising Elon Musk's "unusually firm commitment to free and open debate" after the billionaire took over social media platform X. PLATFORM COLLABORATION ON CONTENT Ferguson has expressed concern that social media platforms may have coordinated in banning Trump in 2021, taking down posts they deemed harmful during the COVID-19 pandemic, and restricting dissemination of stories about Hunter Biden's laptop computer. "If the platforms colluded amongst each other to set shared censorship policies, such an agreement would be tantamount to an agreement not to compete on contract terms or product quality," which would violate antitrust laws, Ferguson said. ADVERTISER COORDINATION Coordination between advertisers to pull money from platforms such as X over content concerns could violate antitrust laws, Ferguson said. The World Federation of Advertisers' Global Alliance for Responsible Media, which was formed to help advertisers avoid their ads being placed next to harmful content on social media, shut down after X sued, accusing it of facilitating group boycotts. Ferguson has said the FTC could investigate similar efforts. KIDS AND TEENS ONLINE Congress should pass a law that would require online service providers to give parents more control over children's online privacy, Ferguson said. "Congress should empower parents to impose whatever level of supervision and control over internet messaging they feel is right for their family and their children," he said. (Reporting by Jody Godoy in New York; Editing by Matthew Lewis)As the gavel fell and the bidding war came to a close, the ruby slippers found a new home with a lucky collector who will undoubtedly cherish and preserve them for generations to come. Their sale not only set a new benchmark for the value of film memorabilia but also reaffirmed the lasting power of storytelling and the emotional connections we form with the objects that bring our favorite films to life.Court challenge over vote to extend post-Brexit trading arrangements dismissed
In a recent development, Manchester United has decided to abolish the position of a sporting director within the club. This decision marks a significant shift in the management structure as the club aims to streamline its operations and decision-making process. The move has sparked a debate among fans and analysts, with many questioning the implications it may have on the club's future performance and strategic planning.ANN ARBOR, Mich. (AP) — Michigan's defense of the national championship has fallen woefully short. The Wolverines started the season ranked No. 9 in the AP Top 25 , making them the third college football team since 1991 to be ranked worse than seventh in the preseason poll after winning a national title. Michigan (6-5, 4-4 Big Ten) failed to meet those modest expectations, barely becoming eligible to play in a bowl and putting the program in danger of losing six or seven games for the first time since the Brady Hoke era ended a decade ago. The Wolverines potentially can ease some of the pain with a win against rival and second-ranked Ohio State (10-1, 7-1, No. 2 CFP) on Saturday in the Horseshoe, but that would be a stunning upset. Ohio State is a 21 1/2-point favorite, according to the BetMGM Sportsbook, and that marks just the third time this century that there has been a spread of at least 20 1/2 points in what is known as “The Game.” Michigan coach Sherrone Moore doesn't sound like someone who is motivating players with an underdog mentality. “I don’t think none of that matters in this game,” Moore said Monday. “It doesn’t matter the records. It doesn’t matter anything. The spread, that doesn’t matter.” How did Michigan end up with a relative mess of a season on the field, coming off its first national title since 1997? Winning it all with a coach and star player contemplating being in the NFL for the 2024 season seemed to have unintended consequences for the current squad. The Wolverines closed the College Football Playoff with a win over Washington on Jan. 8; several days later quarterback J.J. McCarthy announced he was skipping his senior season; and it took more than another week for Jim Harbaugh to bolt to coach the Los Angeles Chargers. In the meantime, most quality quarterbacks wanting to transfer had already enrolled at other schools and Moore was left with lackluster options. Davis Warren beat out Alex Orji to be the team's quarterback for the opener and later lost the job to Orji only to get it back again. No matter who was under center, however, would've likely struggled this year behind an offensive line that sent six players to the NFL. The Wolverines lost one of their top players on defense, safety Rod Moore, to a season-ending injury last spring and another one, preseason All-America cornerback Will Johnson, hasn't played in more than a month because of an injury. The Buckeyes are not planning to show any mercy after losing three straight in the series. “We’re going to attack them," Ohio State defensive end Jack Sawyer said. “We know they’re going to come in here swinging, too, and they’ve still got a good team even though the record doesn’t indicate it. This game, it never matters what the records are." While a win would not suddenly make the Wolverines' season a success, it could help Moore build some momentum a week after top-rated freshman quarterback Bryce Underwood flipped his commitment from LSU to Michigan. “You come to Michigan to beat Ohio,” said defensive back Quinten Johnson, intentionally leaving the word State out when referring to the rival. "That's one of the pillars of the Michigan football program. “It doesn’t necessarily change the fact of where we are in the season, but it definitely is one of the defining moments of your career here at Michigan.” AP Sports Writer Mitch Stacy in Columbus, Ohio, contributed to this report. Get alerts on the latest AP Top 25 poll throughout the season. Sign up here . AP college football: https://apnews.com/hub/college-football and https://apnews.com/hub/ap-top-25-college-football-poll
The new partnership will unveil ScreenX and 4DX theaters in El Segundo , Folsom , and Concord, California HOLLYWOOD, Calif. , Nov. 21, 2024 /PRNewswire/ -- CJ 4DPLEX , the world's leading producer of premium film formats and cinema technologies, has partnered with Cinema West, an independently owned movie theater company with locations throughout California and Idaho , to launch a new lineup of premium auditoriums. This collaboration will introduce three expansive 270-degree panoramic ScreenX theaters, starting with Cinema West's Palladio 16 Cinema in Folsom, CA , which will open this week featuring the highly anticipated film "Wicked" from Universal Pictures. The CinemaWest Beach Cities location in El Segundo, CA , and the Veranda Luxe Cinema in Concord, CA , are both scheduled to open in December. Additionally, two state-of-the-art 4DX auditoriums will be established at the CinemaWest Beach Cities location in El Segundo and Palladio 16 Cinema in Folsom , with expected openings early next year. The CinemaWest Beach Cities location, servicing the Manhattan , Hermosa, & Redondo Beach neighborhoods, formerly known as ArcLight Beach Cities, is the latest addition to the exhibitor's portfolio and is poised to make a significant impact upon its opening. This location has undergone extensive renovations and upgrades, featuring ScreenX and 4DX auditoriums as part of its top premium offerings. "With ScreenX and 4DX, we will showcase the future of cinema, delivering unforgettable and upscale experiences. There is no other cinema experience like CJ 4DPLEX's ScreenX and 4DX technologies, which dramatically highlight the difference between cinema and home viewing. These exceptional cinema innovations will set our complexes apart from the rest in the important Los Angeles market," said Dave Corkill , President, and CEO of Cinema West. "The addition of a ScreenX and 4DX auditorium to the beautifully remodeled CinemaWest Beach Cities perfectly complements the needs of moviegoers seeking next-generation, super-premium offerings that are distinct from the home viewing experience," said Don Savant , CEO and President of CJ 4DPLEX Americas. "The Beach Cities location has a remarkable legacy, and we are excited to partner with Cinema West to deliver both our cutting-edge premium experiences to moviegoers in the South Bay area of Los Angeles . We are also looking forward to launching our super-premium experiences at Cinema West's Concord and Folsom locations." The ScreenX format lets moviegoers experience key scenes from each film in a stunning, 270-degree panoramic view that is displayed across dual-sided screens. This creates all-encompassing visuals like never before and provides the most differentiated and premium moviegoing experience available. 4DX pushes movie-going boundaries through a multi-sensory experience that incorporates motion-based seating synchronized with more than 21 different effects. 4DX connects audiences with movies through motion, vibration, water, wind, snow, lightning, scents, and other special effects that enhance the visuals on-screen. Upcoming titles in ScreenX and 4DX include Universal Pictures Wicked , Paramount's Gladiator 2 and Sonic The Hedgehog 3 , Disney's Moana 2 and Mufasa: The Lion King and Sony's Kraven The Hunter . About CJ 4DPLEX: CJ 4DPLEX is a leading, next-generation cinema technology company, headquartered in Seoul with international offices in Los Angeles and Beijing . The company has created innovative film technologies for theaters worldwide that include 'ScreenX', '4DX', and '4DX Screen' for consumers to experience films in ways that were never before possible. CJ 4DPLEX is a part of the CJ Group conglomerate that also includes entertainment powerhouses CJ CGV, the fifth largest theater chain in the world, and CJ ENM (CJ Entertainment & Media), who produced the Academy Award®, Golden Globe® and SAG Awards winning film, "Parasite". ScreenX is the world's first multi-projection cinema with an immersive 270 degree field of view. By expanding the image beyond the frame and onto the walls of the theater, ScreenX places the audience directly at the center of the story, creating a visually immersive viewing experience unlike any other. To date, there are over 370 ScreenX auditoriums around the world in 40 countries. 4DX provides moviegoers with a multi-sensory cinema-going experience, allowing audiences to connect with movies through motion, vibration, water, wind, snow, lightning, scents, and other special effects that enhance the visuals on-screen. Each 4DX auditorium incorporates motion-based seating synchronized with more than 21 different effects and optimized by a team of skilled editors. To date, there are over 790 4DX auditoriums around the world, spanning over 70 countries. About Cinema West: Headquartered in Petaluma, CA , Cinema West is a privately owned company that owns and operates 18 locations throughout California and Idaho . View original content to download multimedia: https://www.prnewswire.com/news-releases/cj-4dplex-and-cinema-west-sign-multi-theater-deal-to-launch-270-degree-panoramic-screenx-and-multisensory-4dx-auditoriums-across-california-302313629.html SOURCE CJ 4DPLEX
AGNC Investment Corp. Declares Monthly Common Stock Dividend of $0.12 per Common Share for December 2024CAMBRIDGE, Mass., Dec. 09, 2024 (GLOBE NEWSWIRE) -- Relay Therapeutics, Inc. (Nasdaq: RLAY), a clinical-stage precision medicine company transforming the drug discovery process by combining leading-edge computational and experimental technologies, today announced that updated clinical data for RLY-2608 600mg BID + fulvestrant in patients with PI3Kα-mutated, HR+, HER2- locally advanced or metastatic breast cancer will be presented at the upcoming San Antonio Breast Cancer Symposium, taking place December 10-13, 2024. Details of the RLY-2608 + fulvestrant poster presentation are as follows: Abstract Title : PS7-01: Efficacy of RLY-2608, a mutant-selective PI3Kα inhibitor in patients with PIK3CA-mutant HR+HER2- advanced breast cancer: ReDiscover trial Abstract Number: SESS-2211 Session : Concurrent Poster Spotlight Session 7: Targeting the ER and PI3K pathway: Novel drugs and combinations Date/Time : Wednesday, December 11, 8:00-9:30 a.m. ET (7:00-8:30 a.m. CT) Conference Call Information Relay Therapeutics will host a conference call to discuss these data on Wednesday, December 11, 2024 at 7:00 a.m. ET (6:00 a.m. CT). Registration and dial-in for the conference call and webcast may be accessed through Relay Therapeutics’ website under Events in the News & Events section through the following link: https://ir.relaytx.com/news-events/events-presentations . An archived replay of the webcast will be available following the event. The poster will be available at the start of the session on the company’s website at https://relaytx.com/publications/ . About RLY-2608 RLY-2608 is the lead program in Relay Therapeutics’ efforts to discover and develop mutant selective inhibitors of PI3Kα, the most frequently mutated kinase in all cancers, with oncogenic mutations detected in about 14% of patients with solid tumors. RLY-2608 has the potential, if approved, to address more than 300,000 patients per year in the United States, one of the largest patient populations for a precision oncology medicine. Traditionally, the development of PI3Kα inhibitors has focused on the active, or orthosteric, site. The therapeutic index of orthosteric inhibitors is limited by the lack of clinically meaningful selectivity for mutant versus wild-type (WT) PI3Kα and off-isoform activity. Toxicity related to inhibition of WT PI3Kα and other PI3K isoforms results in sub-optimal inhibition of mutant PI3Kα with reductions in dose intensity and frequent discontinuation. The Dynamo® platform enabled the discovery of RLY-2608, the first known allosteric, pan-mutant, and isoform-selective PI3Kα inhibitor, designed to overcome these limitations. Relay Therapeutics solved the full-length cryo-EM structure of PI3Kα, performed computational long time-scale molecular dynamic simulations to elucidate conformational differences between WT and mutant PI3Kα, and leveraged these insights to support the design of RLY-2608. RLY-2608 is currently being evaluated in a first-in-human trial designed to treat patients with advanced solid tumors with a PIK3CA (PI3Kα) mutation. For more information on RLY-2608, please visit here . About Relay Therapeutics Relay Therapeutics is a clinical-stage precision medicine company transforming the drug discovery process by combining leading-edge computational and experimental technologies with the goal of bringing life-changing therapies to patients. As the first of a new breed of biotech created at the intersection of complementary techniques and technologies, Relay Therapeutics aims to push the boundaries of what’s possible in drug discovery. Its Dynamo® platform integrates an array of leading-edge computational and experimental approaches designed to drug protein targets that have previously been intractable or inadequately addressed. Relay Therapeutics’ initial focus is on enhancing small molecule therapeutic discovery in targeted oncology and genetic disease indications. For more information, please visit www.relaytx.com or follow us on Twitter . Cautionary Note Regarding Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including, without limitation, implied and express statements regarding Relay Therapeutics’ strategy, business plans and focus; the progress and timing of the clinical development of the programs across Relay Therapeutics’ portfolio; the expected therapeutic benefits and potential efficacy and tolerability of RLY-2608, both as a monotherapy and in combination with other agents, and its other programs, including lirafugratinib as well as the clinical data for RLY-2608; the interactions with regulatory authorities and any related approvals; the potential market opportunity for RLY-2608; the cash runway projection and the expectations regarding Relay Therapeutics’ use of capital, expenses and potential cost savings. The words “may,” “might,” “will,” “could,” “would,” “should,” “plan,” “anticipate,” “intend,” “believe,” “expect,” “estimate,” “seek,” “predict,” “future,” “project,” “potential,” “continue,” “target” and similar words or expressions, or the negative thereof, are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements in this press release are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and important factors that may cause actual events or results to differ materially from those expressed or implied by any forward-looking statements contained in this press release, including, without limitation, risks associated with: the impact of global economic uncertainty, geopolitical instability and conflicts, or public health epidemics or outbreaks of an infectious disease on countries or regions in which Relay Therapeutics has operations or does business, as well as on the timing and anticipated results of its clinical trials, strategy, future operations and profitability; the delay or pause of any current or planned clinical trials or the development of Relay Therapeutics’ drug candidates; the risk that the preliminary or interim results of its preclinical or clinical trials may not be predictive of future or final results in connection with future clinical trials of its product candidates and that interim and early clinical data may change as more patient data become available and are subject to audit and verification procedures; Relay Therapeutics’ ability to successfully demonstrate the safety and efficacy of its drug candidates; the timing and outcome of its planned interactions with regulatory authorities; and obtaining, maintaining and protecting its intellectual property. These and other risks and uncertainties are described in greater detail in the section entitled “Risk Factors” in Relay Therapeutics’ most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q, as well as any subsequent filings with the Securities and Exchange Commission. In addition, any forward-looking statements represent Relay Therapeutics' views only as of today and should not be relied upon as representing its views as of any subsequent date. Relay Therapeutics explicitly disclaims any obligation to update any forward-looking statements. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. Contact: Megan Goulart 617-322-0814 mgoulart@relaytx.com Media : Dan Budwick 1AB 973-271-6085 dan@1abmedia.com
The inclusion of language-focused programs in the selection process is seen as a significant departure from previous years, signaling a shift towards greater cultural diversity and inclusivity in the gala lineup. This move has been met with enthusiasm by many, who see it as a positive step towards broadening the scope of content featured in the annual event.
Wang Sicong's Company Faces Forced Execution for 148,000 RMB Debt and Multiple Risk FactorsRegardless of the outcome, one thing is certain – the reunion of old teammates in the same group has reignited the flames of nostalgia and rivalry in the esports community. It serves as a reminder of the bonds and memories forged through countless hours of practice and competition, and the enduring passion and dedication that drive players to strive for greatness.
In conclusion, Xiang Zuo's recent haircut by Zhao Xiaohua not only received positive feedback from fans but also brought double happiness for the celebrity chef duo as they reunited in the kitchen to showcase their culinary talents once again. Their unwavering passion for food, cooking, and each other continues to captivate audiences, making them a force to be reckoned with in the world of entertainment and gastronomy.Ex-Colorado footballer Bloom dedicates time to fulfilling wishes for older adults
The significance of the ruby slippers extends far beyond their aesthetic appeal. They represent a symbol of hope, magic, and the power of believing in oneself. In The Wizard of Oz, Dorothy's journey to the Emerald City and back home to Kansas is guided by the magic of the ruby slippers, which have the power to transport her wherever she wishes to go. The shoes serve as a reminder that with courage, determination, and a little bit of magic, anything is possible.Court challenge over vote to extend post-Brexit trading arrangements dismissed
The Onion's rejected purchase of Infowars in an auction bid supported by families of the Sandy Hook Elementary shooting dealt them a new setback Wednesday and clouded the future of Alex Jones' conspiracy theory platform, which is now poised to remain in his control for at least the near future. What's next for Infowars and Sandy Hook families' long-sought efforts to hold Jones accountable over calling one of the deadliest school shootings in U.S. history a hoax was unclear, after a federal judge in Houston late Tuesday rejected The Onion's winning bid for the site. U.S. Bankruptcy Judge Christopher Lopez in Houston said he did not want another auction but offered no roadmap over how to proceed. One possibility includes ultimately allowing Sandy Hook families — who comprise most of Jones' creditors — to return to state courts in Connecticut and Texas to collect on the nearly $1.5 billion in defamation and emotional distress lawsuit judgments that Jones was ordered to pay them. "Our hope is that when this process ends, and it will end, and it will end sooner rather than later, is that all assets that Alex Jones has available are paid to the families, and that includes Infowars, and that as a result of that process Alex Jones is deprived of the ownership and control of the platform that he's used to hurt so many people," Christopher Mattei, an attorney for the Sandy Hook families, said in a phone interview Wednesday. The families, meanwhile, were preparing the mark the 12th anniversary of the Dec. 14 shooting. Why was The Onion bid rejected? The sale of Infowars is part of Jones' personal bankruptcy case, which he filed in late 2022 after he was ordered to pay the $1.5 billion. Jones was sued for repeatedly saying on his show that the 2012 massacre of 20 first graders and six educators was staged by crisis actors to spur more gun control. Lopez said there was a lack of transparency in the bidding process and too much confusion about The Onion's bid. He also said the amount of money offered in the only two bids was too low and there needed to be more effort to try to raise as much money possible from the selling of Infowars' assets. The Onion's parent company, Global Tetrahedron, submitted a $1.75 million cash offer with plans to kick Jones out and relaunch Infowars in January as a parody. The bid also included a deal with many of the Sandy Hook families for them to forgo $750,000 of their auction proceeds and give it to other creditors. Lopez called it a complex arrangement that led to different interpretations of the bid's actual value as well as last-minute changes to a proposed sale order. The other bidder was First United American Companies, which runs a website in Jones' name that sells nutritional supplements and planned to let Jones stay on the Infowars platforms. It offered $3.5 million in cash and later, with Jones, alleged fraud and collusion in the bidding process. Lopez rejected the allegations, saying that while mistakes were made there was no wrongdoing. Christopher Murray, the trustee who oversaw the auction, said he picked The Onion and its deal with the Sandy Hook families because it would have provided more money to Jones' other creditors. What happens next? The next steps remained unclear Wednesday. The judge directed Murray to come up with a new plan to move forward. Murray and representatives of The Onion did not immediately return messages seeking comment. The judge said there was a possibility there could be a trial in 2025 to settle Jones' bankruptcy. He said Murray could try to sell the equity in Infowars' parent company. He also said Murray could abandon the efforts, which could allow the Sandy Hook families to return to the state courts where they won their lawsuits against Jones and begin collection proceedings against him. The judge said he wanted to hear back from Murray and others involved in the bankruptcy within 30 days on a plan to move forward. Mattei, who represented the Sandy Hook families in the Connecticut lawsuit, said everyone is waiting to see what plan the trustee comes up with. Jones, meanwhile, continued to allege fraud and collusion on his show Wednesday and threatened legal action over what he called an attempted "rigged auction." On the social media platform X, he called the judge's ruling a "Major Victory For Freedom Of The Press & Due Process." "I don't want to have to go after these people, lawsuit-wise, but we have to because if you don't then you're aiding and abetting and they do it to other people. They made some big mistakes," he said. Sandy Hook families to mark shooting anniversary It's a solemn and heartbreaking week for relatives of victims of the Sandy Hook shooting in Newtown, Connecticut. The 12th anniversary is Saturday, and some of the victims' relatives were traveling to Washington, D.C., to attend the annual National Vigil for All Victims of Gun Violence on Wednesday evening. The families usually mark the anniversary out of the public eye. Many of the families said their lawsuits against Jones bought back the unbearable pain of losing their loved ones, as well as the trauma of being harassed and threatened by believers of Jones' hoax conspiracy. Relatives said they have been confronted in public by hoax believers and received death and rape threats. Robbie Parker, whose 6-year-old daughter Emilie was killed, testified at the Connecticut lawsuit trial in 2022 that the decade of abuse his family suffered made them move across the country to Washington state, and even there he was accosted in person. The families have not received any money from Jones since winning the trials. Jones has been appealing the $1.5 billion in judgments, and has since conceded that the shooting did happen. Last week, a Connecticut appeals court upheld most of the judgment in that state but reduced it by $150 million.