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Dyskinetic Cerebral Palsy: A Closer Look at Symptoms, Diagnosis and Clinical Research UnderwayFranklin Resources Inc. bought a new stake in shares of TORM plc ( NASDAQ:TRMD – Free Report ) in the third quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission. The institutional investor bought 32,974 shares of the company’s stock, valued at approximately $1,047,000. Other hedge funds have also recently added to or reduced their stakes in the company. Centiva Capital LP acquired a new stake in shares of TORM during the third quarter worth $3,077,000. DekaBank Deutsche Girozentrale grew its holdings in TORM by 1,166.7% during the 3rd quarter. DekaBank Deutsche Girozentrale now owns 38,000 shares of the company’s stock worth $1,289,000 after acquiring an additional 35,000 shares during the period. International Assets Investment Management LLC bought a new position in shares of TORM in the 3rd quarter worth about $7,359,000. Lighthouse Investment Partners LLC lifted its stake in shares of TORM by 276.2% in the 2nd quarter. Lighthouse Investment Partners LLC now owns 110,049 shares of the company’s stock valued at $4,267,000 after purchasing an additional 80,793 shares during the period. Finally, Hsbc Holdings PLC bought a new stake in shares of TORM during the 2nd quarter valued at about $9,619,000. Institutional investors own 73.89% of the company’s stock. TORM Stock Performance Shares of TRMD opened at $19.34 on Friday. TORM plc has a one year low of $17.77 and a one year high of $40.47. The company has a market cap of $1.58 billion, a PE ratio of 2.50 and a beta of 0.21. The stock has a 50-day moving average of $22.39 and a 200-day moving average of $31.18. The company has a debt-to-equity ratio of 0.51, a current ratio of 2.47 and a quick ratio of 2.24. TORM Cuts Dividend Analyst Ratings Changes TRMD has been the subject of a number of research analyst reports. Fearnley Fonds upgraded TORM to a “hold” rating in a report on Friday, September 27th. Jefferies Financial Group lowered their price objective on shares of TORM from $37.00 to $32.00 and set a “buy” rating for the company in a research note on Thursday, November 14th. Read Our Latest Analysis on TRMD TORM Profile ( Free Report ) TORM plc, a shipping company, owns and operates a fleet of product tankers in the United Kingdom. It operates in two operating segments, Tanker and Marine Exhaust. The Tanker segment transports refined oil products, such as gasoline, jet fuel, kerosene, naphtha, and gas oil, as well as dirty petroleum products, including fuel oil. Featured Stories Five stocks we like better than TORM Dividend Capture Strategy: What You Need to Know Buffett Takes the Bait; Berkshire Buys More Oxy in December How to Calculate Return on Investment (ROI) Top 3 ETFs to Hedge Against Inflation in 2025 EV Stocks and How to Profit from Them These 3 Chip Stock Kings Are Still Buys for 2025 Want to see what other hedge funds are holding TRMD? Visit HoldingsChannel.com to get the latest 13F filings and insider trades for TORM plc ( NASDAQ:TRMD – Free Report ). Receive News & Ratings for TORM Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for TORM and related companies with MarketBeat.com's FREE daily email newsletter .Serhiy Tokarev Explains Why Health Tech Startups Are Worth Investing Ingame 2 player

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Hope is fragile as Assad fallsFranklin Resources Inc. decreased its stake in Fidelis Insurance Holdings Limited ( NYSE:FIHL – Free Report ) by 11.4% in the 3rd quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund owned 55,770 shares of the company’s stock after selling 7,191 shares during the period. Franklin Resources Inc.’s holdings in Fidelis Insurance were worth $1,027,000 at the end of the most recent quarter. Other hedge funds have also recently added to or reduced their stakes in the company. Ashton Thomas Private Wealth LLC bought a new position in shares of Fidelis Insurance in the 2nd quarter valued at $140,000. Y Intercept Hong Kong Ltd acquired a new position in Fidelis Insurance in the 3rd quarter worth about $195,000. Summit Global Investments bought a new position in Fidelis Insurance in the third quarter valued at about $238,000. Caprock Group LLC acquired a new stake in shares of Fidelis Insurance during the second quarter valued at about $265,000. Finally, Intech Investment Management LLC bought a new stake in shares of Fidelis Insurance during the third quarter worth about $269,000. Institutional investors and hedge funds own 81.99% of the company’s stock. Analysts Set New Price Targets FIHL has been the topic of several recent research reports. The Goldman Sachs Group initiated coverage on shares of Fidelis Insurance in a research report on Tuesday, September 17th. They set a “neutral” rating and a $18.50 target price on the stock. Keefe, Bruyette & Woods boosted their price objective on shares of Fidelis Insurance from $25.00 to $26.00 and gave the stock an “outperform” rating in a research note on Thursday, November 14th. Finally, Barclays began coverage on Fidelis Insurance in a research report on Wednesday, September 4th. They set an “equal weight” rating and a $21.00 target price for the company. Three investment analysts have rated the stock with a hold rating and three have issued a buy rating to the company. According to data from MarketBeat.com, Fidelis Insurance currently has a consensus rating of “Moderate Buy” and a consensus target price of $21.50. Fidelis Insurance Price Performance Shares of NYSE FIHL opened at $17.61 on Friday. The company has a quick ratio of 0.68, a current ratio of 0.68 and a debt-to-equity ratio of 0.17. The company has a market capitalization of $2.08 billion, a PE ratio of 4.45 and a beta of 0.30. The firm has a fifty day simple moving average of $18.79 and a 200 day simple moving average of $17.92. Fidelis Insurance Holdings Limited has a twelve month low of $11.80 and a twelve month high of $21.32. Fidelis Insurance Announces Dividend The firm also recently announced a quarterly dividend, which was paid on Friday, December 20th. Investors of record on Friday, November 29th were given a dividend of $0.10 per share. The ex-dividend date of this dividend was Friday, November 29th. This represents a $0.40 annualized dividend and a dividend yield of 2.27%. Fidelis Insurance’s payout ratio is 10.10%. Fidelis Insurance Company Profile ( Free Report ) Fidelis Insurance Holdings Limited, a specialty insurer, provides insurance and reinsurance solutions in Bermuda, the Republic of Ireland, and the United Kingdom. It operates in three segments: Specialty, Reinsurance, and Bespoke segments. The Specialty segment offers aviation and aerospace, energy, marine, property direct and facultative, and other specialty risk solutions. Featured Stories Five stocks we like better than Fidelis Insurance Utilities Stocks Explained – How and Why to Invest in Utilities Buffett Takes the Bait; Berkshire Buys More Oxy in December Special Purpose Acquisition Company (SPAC) What You Need to Know Top 3 ETFs to Hedge Against Inflation in 2025 REIT Stocks – Best REIT Stocks to Add to Your Portfolio Today These 3 Chip Stock Kings Are Still Buys for 2025 Want to see what other hedge funds are holding FIHL? Visit HoldingsChannel.com to get the latest 13F filings and insider trades for Fidelis Insurance Holdings Limited ( NYSE:FIHL – Free Report ). Receive News & Ratings for Fidelis Insurance Daily - Enter your email address below to receive a concise daily summary of the latest news and analysts' ratings for Fidelis Insurance and related companies with MarketBeat.com's FREE daily email newsletter .

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DBG Announces First 45 Day Results with VAYNERCOMMERCE resulting in a 224% increase in digital revenueNEW YORK (AP) — Stocks rose in afternoon trading on Wall Street Friday, keeping the market on track for its fifth gain in a row. The S&P 500 was up 0.4% and is solidly on track for a weekly gain that will erase most of last week's loss. The Dow Jones Industrial Average climbed 351 points, or 0.8%, and the Nasdaq composite rose 0.2% as of 1:03 p.m. Eastern. Markets have been volatile over the last few weeks, losing ground in the runup to elections in November, then surging following Donald Trump's victory, before falling again. The S&P 500 has been steadily rising throughout this week to within close range of its record. “Overall, market behavior has normalized following an intense few weeks,” said Mark Hackett, chief of investment research at Nationwide, in a statement. Several retailers jumped after giving Wall Street encouraging financial updates. Gap soared 10.6% after handily beating analysts' third-quarter earnings and revenue expectations, while raising its own revenue forecast for the year. Discount retailer Ross Stores rose 3.1% after raising its earnings forecast for the year. EchoStar fell 3.4% after DirecTV called off its purchase of that company's Dish Network unit. Smaller company stocks had some of the biggest gains. The Russell 2000 index rose 1.7%. A majority of stocks in the S&P 500 were gaining ground, but those gains were kept in check by slumps for several big technology companies. Nvidia fell 3.2%. Its pricey valuation makes it among the heaviest influences on whether the broader market gains or loses ground. The company has grown into a nearly $3.6 trillion behemoth because of demand for its chips used in artificial-intelligence technology. Intuit, which makes TurboTax and other accounting software, fell 4.1%. It gave investors a quarterly earnings forecast that fell short of analysts’ expectations. Facebook owner Meta Platforms fell 0.4% following a decision by the Supreme Court to allow a multibillion-dollar class action investors’ lawsuit to proceed against the company. It stems from the privacy scandal involving the Cambridge Analytica political consulting firm. European markets were mostly higher and Asian markets ended mixed. Crude oil prices rose. Treasury yields held relatively steady in the bond market. The yield on the 10-year Treasury fell to 4.41% from 4.42% late Thursday. In the crypto market, Bitcoin hovered around $99,000, according to CoinDesk. It has more than doubled this year and first surpassed the $99,000 level on Thursday. Retailers remained a big focus for investors this week amid close scrutiny on consumer spending habits headed into the holiday shopping season. Walmart, the nation's largest retailer, reported a quarter of strong sales and gave investors an encouraging financial forecast. Target, though, reported weaker earnings than analysts' expected and its forecast disappointed Wall Street. Consumer spending has fueled economic growth, despite a persistent squeeze from inflation and high borrowing costs. Inflation has been easing and the Federal Reserve has started trimming its benchmark interest rates. That is likely to help relieve pressure on consumers, but any major shift in spending could prompt the Fed to reassess its path ahead on interest rates. Also, any big reversals on the rate of inflation could curtail spending. Consumer sentiment remains strong, according to the University of Michigan's consumer sentiment index. It revised its latest figure for November to 71.8 from an initial reading of 73 earlier this month, though economists expected a slight increase. It's still up from 70.5 in October. The survey also showed that consumers' inflation expectations for the year ahead fell slightly to 2.6%, which is the lowest reading since December of 2020. Wall Street will get another update on how consumers feel when the business group The Conference Board releases its monthly consumer confidence survey on Tuesday. A key inflation update will come on Wednesday when the U.S. releases its October personal consumption expenditures index. The PCE is the Fed's preferred measure of inflation and this will be the last PCE reading prior to the central bank's meeting in December.Taoiseach Simon Harris said he also wanted to tell Nikita Hand, a hair colourist from Drimnagh, that her case had prompted an increase in women coming forward to ask for support. Ms Hand, who accused the sportsman of raping her in a Dublin hotel in December 2018, won her claim against him for damages in a civil case at the High Court in the Irish capital on Friday. The total amount of damages awarded to Ms Hand by the jury was 248,603.60 euro (£206,714.31). Mr McGregor said in a post on the social media site X on Friday that he intends to appeal against the decision. That post has since been deleted. Mr McGregor posted to X again on Saturday to criticise the court process and said “we are not done yet... appeal!”. Speaking to the media on Saturday, Mr Harris said he told Ms Hand of the support she has from people across Ireland. “I spoke with Nikita today and I wanted to thank her for her incredible bravery and her courage,” he said. “I wanted to make sure that she knew how much solidarity and support there was across this country for her bravery. “I also wanted to make sure she knew of what the Dublin Rape Crisis Centre had said yesterday – that so many other women have now come forward in relation to their own experiences of sexual abuse as a result of Nikita’s bravery.” The Dublin Rape Crisis Centre said the case has had a “profound effect” on the people the charity supports, and that over the first 10 days of the High Court case, calls to its national helpline increased by almost 20%. It said that first-time callers increased by 50% compared to the same period last year, and were largely from people who had experienced sexual violence who were distressed and anxious from the details of case and the views people had to it. Mr Harris said: “I wanted to speak with her and I wanted to wish her and her daughter, Freya, all the very best night, and I was very grateful to talk with Nikita today. “Her bravery, her courage, her voice has made a real difference in a country in which we must continue to work to get to zero tolerance when it comes to domestic, sexual and gender-based violence. “I don’t want to say too much more, because conscious there could be further legal processes, but I absolutely want to commend Nikita for her bravery, for her courage, for using her voice.” Justice Minister Helen McEntee praised Ms Hand’s bravery and said she had shown “there is light at the end of the tunnel”. She said: “I just want to commend Nikita for her bravery, for her determination and the leadership that she has shown in what has been – I’ve no doubt – a very, very difficult time for her and indeed, for her family. She added: “Because of wonderful people like Nikita, I hope that it shows that there is light at the end of the tunnel, that there are supports available to people, and that there is justice at the end of the day.” Ms Hand said in a statement outside court on Friday that she hoped her case would remind victims of assault to keep “pushing forward for justice”. Describing the past six years as “a nightmare”, she said: “I want to show (my daughter) Freya and every other girl and boy that you can stand up for yourself if something happens to you, no matter who the person is, and justice will be served.” During the case, Ms Hand said she was “disappointed and upset” when the Director of Public Prosecutions (DPP) decided not to prosecute the case after she made a complaint to the Irish police. In a letter to her in August 2020, the DPP said there was “insufficient evidence” and there was not a reasonable prospect of conviction. Ms Hand asked the DPP to review the decision, saying she felt she was being treated differently because one of the suspects was famous. Asked about the DPP’s decision not to prosecute, Mr Harris and Ms McEntee stressed the importance of the DPP’s independence on whether to prosecute. “There are obviously structures in place where the DPP can meet a victim and can outline to them their reasons for not taking the case,” Mr Harris said. “But there’s also always an opportunity for the DPP in any situation – and I speak broadly in relation to this – to review a decision, to consider any new information that may come to light, and I don’t want to say anything that may ever cut across the ongoing work of the DPP.” Ms McEntee stressed that there should “never be any political interference” in the independence of the DPP’s decisions. “I have, since becoming minister, given priority to and enabled a new office within the DPP to open specifically focused on sexual offences, so that this issue can be given the focus and the priority that it needs,” she said.

(BPT) - This article was sponsored and developed by Neurocrine Biosciences, Inc. Cerebral palsy (CP) is a neurodevelopmental disorder affecting movement and posture that begins in early childhood development. It is the most common cause of motor disability in children, affecting about one in 345 children in the United States. 1-2 It may happen as a result of lack of oxygen during or around birth, stroke, infection, a problem with metabolism or other problems that cause injury or affect the development of parts of the brain involved in movement control in the first few years of life. 3 CP is a permanent condition, affecting a person for their entire life. People living with CP typically have motor problems, which may include spasticity (abnormal muscle tightness), dyskinesia (uncontrolled movements) or ataxia (poor muscle control), and many people have a mix of these motor disorders. 4 Dyskinesia due to CP (DCP) is one of the most disabling forms of CP and impacts approximately 10% to 20% of people living with CP. 5-6 According to the Cerebral Palsy Foundation (CPF), the combination of irregular and unpredictable movements (chorea) and twisting and repeating movements (dystonia) often disrupt activities and cause significant functional impairment, including the ability to maintain balance, walk or fine motor control. 7 Heather Riordan, M.D., Neurologist and Movement Disorders Specialist, Director of the Phelps Center for Cerebral Palsy at the Kennedy Krieger Institute, discusses the symptoms of chorea and impact on patients in a video shared on the CPF website here . About 30% of people with DCP are affected mostly by these involuntary and irregular movements (chorea), while dystonia is the predominant motor finding in the remaining 70%. 8 However, it is common for both chorea and dystonia movements to be present together. 6 For people living with DCP, these movements can occur in any region of the body, including the arms and legs, torso and face and may vary in severity. They are often triggered or made worse by stimulation or stress. Because dyskinesia can occur at rest and/or when actively using the body, the problems with movement are very burdensome in day-to-day living, with discomfort and pain affecting the quality of life for people and their caregivers. 9 Jen Lyman, mom to a son with DCP, highlights how dyskinesia makes communicating more difficult. "The most difficult thing about dyskinesia is watching my son struggle to do things that he wants to do, but the extra movements get in the way...special things, such as using a touch screen to video chat with his grandmother, are nearly impossible despite his best efforts to use his hands and fingers. Something so simple, yet so special for him should be effortless." DCP has a wide-ranging impact on the individual, including lifelong challenges with movement, a higher risk of other medical issues, a higher rate of mental health challenges and difficulties with communication. 10-12 "Those of us who have the privilege to serve patients with dyskinetic, hyperkinetic or mixed cerebral palsy see the functional impact of this very challenging type of tone every day," said Susan Biffl, M.D., Rehabilitation Medicine Specialist at Rady Children's Hospital-San Diego and Assistant Professor at UC San Diego School of Medicine. "Patients face challenges with self-care, independence, mobility, communication, fine motor skills that affect occupational and recreational activities, swallowing, social interactions and even sleep. As this tone is variable, it is much more challenging to treat than more consistent tone issues, such as spasticity." Treatment Options There are currently no Food and Drug Administration-approved treatments for DCP. Dystonia and chorea are often managed separately as they respond differently to various treatments, which can make treatment challenging. 3 Most drugs being investigated for DCP have focused on dystonia, and more research is needed to determine potential treatments for chorea. New treatment options are needed to help manage these movement disorders and improve daily function and quality of life for those affected. "After 20 years of caring for individuals with cerebral palsy, I continue to find those with dyskinetic cerebral palsy among the most challenging to treat, largely due to the limited effectiveness of available pharmacologic options," said Joyce Oleszek, M.D., Professor, Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine. "There is an urgent need for more robust evidence to support pharmacologic treatments for this condition, given its profound impact on function, comfort and quality of life." Ongoing Research Clinical studies are important in the development of treatment options, allowing researchers to evaluate the safety and effectiveness of new medicines. The data from clinical studies are used to determine if an investigational treatment can be approved for use to treat certain disorders. There are ongoing clinical studies evaluating potential treatments for DCP, including one for chorea. Neurocrine Biosciences is conducting the KINECT ® -DCP clinical study, a Phase 3, randomized, double-blind placebo-controlled study investigating the study drug, valbenazine, for the treatment of DCP. The clinical study is currently enrolling children, adolescents and adults six to 70 years of age who have been diagnosed with DCP. "The Cerebral Palsy Foundation is excited to partner with Neurocrine Biosciences on this study," said Rachel Byrne, Executive Director of the Cerebral Palsy Foundation. "We are proud to support strong research that can potentially bring meaningful change to the lives of those living with cerebral palsy." If you or someone you know may be eligible for this research study, please visit the study website for additional information here: FindADCPStudy.com . REFERENCES Krigger KW. Cerebral palsy: a review. Am Fam Physician . 2006;73(1):91-100. Michael-Asalu A, Taylor G, Campbell H, Lelea LL, Kirby RS. Cerebral palsy: diagnosis, epidemiology, genetics, and clinical update. Adv Pediatr2019;66:189-208. doi:10.1016/j.yapd.2019.04.002 Monbaliu E, Himmelmann K, Lin JP, et al. Clinical presentation and management of dyskinetic cerebral palsy. Lancet Neurol. 2017;16(9):741-749. doi:10.1016/S1474-4422(17)30252-1 Christine C, Dolk H, Platt MJ, Colver A, Prasauskiene A, Krägeloh-Mann I; SCPE Collaborative Group. Recommendations from the SCPE collaborative group for defining and classifying cerebral palsy. Dev Med Child Neurol Suppl. 2007;109:35-38. doi:10.1111/j.1469-8749.2007.tb12626.x Lumsden DE, Crowe B, Basu A, et al. Pharmacological management of abnormal tone and movement in cerebral palsy. Arch Dis Child . 2019;104(8):775-780. doi:10.1136/archdischild-2018-316309 Monbaliu E, de Cock P, Ortibus E, Heyrman L, Klingels K, Feys H. Clinical patterns of dystonia and choreoathetosis in participants with dyskinetic cerebral palsy. Dev Med Child Neurol. 2016;58(2):138-144. doi:10.1111/dmcn.12846 Dyskinetic cerebral palsy. Cerebral Palsy Foundation. Published December 20, 2022. Accessed October 29, 2024. https://cpresource.org/understanding-cerebral-palsy/types-cerebral-palsy/dyskinetic-cerebral-palsy Himmelmann K, Hagberg G, Wiklund LM, Eek MN, Uvebrant P. Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998. Dev Med Child Neurol. 2007;49(4):246-251. doi:10.1111/j.1469-8749.2007.00246.x Masson R, Pagliano E, Baranello G. Efficacy of oral pharmacological treatments in dyskinetic cerebral palsy: a systematic review. Dev Med Child Neurol . 2017; 59:1237-1248. doi:10.1111/dmcn.13532 What is cerebral palsy? Cerebral Palsy Foundation. Accessed November 13, 2024. https://cpresource.org/topic/what-cerebral-palsy Adults & adolescence. Cerebral Palsy Foundation. Accessed November 13, 2024. https://cpresource.org/topic/adults Communication. Cerebral Palsy Foundation. Accessed November 13, 2024. https://cpresource.org/topic/communication © 2024 Neurocrine Biosciences, Inc. All Rights Reserved. CAP-NBI-US-0115 12/2024 NBI-98854-DCP3018_11DecMatRelease_v1.0_25November2024

NoneSANTA ANA, Calif., Dec. 13, 2024 (SEND2PRESS NEWSWIRE) — In a groundbreaking move for the property management and inspection industry, DrBalcony ( drbalcony.com ) introduces its cutting-edge app, a pioneering digital platform designed to revolutionize the balcony inspection process. This innovative tool empowers homeowners, property managers, and Homeowner Associations (HOAs) with a streamlined, intuitive experience, eliminating inefficiencies and redefining how inspections are managed. With a user-friendly interface and advanced features, the DrBalcony App transforms what was once a complex, time-consuming process into one that is seamless and efficient. Users can now obtain instant quotes, create and manage projects, and schedule inspections—all with just a few taps on their devices. “At DrBalcony, we are passionate about reimagining property management through technology,” said Greg, VP of Sales of DrBalcony. “The app reflects our dedication to simplifying inspections while upholding safety and compliance standards. With over 2,500 inspections completed, we’re proud to offer a solution that sets a new benchmark for convenience and reliability.” FEATURES THAT SET THE DRBALCONY APP APART The DrBalcony App is tailored to meet the specific needs of California property owners, offering features designed to ensure the integrity of balcony structures while making compliance with state laws like SB 721 and SB 326 more accessible than ever. Learn more: https://drbalcony.com/services/ A SOLUTION BACKED BY REAL RESULTS “For years, the balcony inspection process has been frustrating and inefficient,” shared Omid, CEO of DrBalcony. “This app eliminates unnecessary complications. From instant quotes to straightforward scheduling, it’s a game-changer.” DOWNLOAD THE DRBALCONY APP TODAY The DrBalcony App is now available for download and marks a significant leap forward in property management. By addressing common pain points in the inspection process, DrBalcony ensures peace of mind for property owners, engineers, and HOAs, all while maintaining safety and compliance with California’s strict balcony safety regulations . About DrBalcony: DrBalcony leverages innovative technology to enhance balcony inspection, focusing on efficiency, safety, and customer-centric solutions. With a mission to simplify the complex, DrBalcony has become a trusted name in the balcony inspection industry, ensuring compliance and safety standards are met with ease. Learn more: https://drbalcony.com/ . Your property’s safety has never been simpler—download the DrBalcony App today! NEWS SOURCE: DrBalcony Keywords: Real Estate, DrBalcony, Balcony Inspections, home inspection, safety, app, solution, service, SB 326, SB 721, SANTA ANA, Calif. This press release was issued on behalf of the news source (DrBalcony) who is solely responsibile for its accuracy, by Send2Press® Newswire . Information is believed accurate but not guaranteed. Story ID: S2P122836 APDF15TBLLI To view the original version, visit: https://www.send2press.com/wire/drbalcony-app-redefines-balcony-inspections-with-unparalleled-efficiency/ © 2024 Send2Press® Newswire, a press release distribution service, Calif., USA. Disclaimer: This press release content was not created by nor issued by the Associated Press (AP). Content below is unrelated to this news story.


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