Ship strikes kill thousands of whales. A study of hot spots could map out solutionsPLEASANTON, Calif. , Dec. 23, 2024 /PRNewswire/ -- 10x Genomics, Inc. (Nasdaq: TXG), a leader in single cell and spatial biology, announced today it had secured a permanent injunction in the U.S. District Court for the District of Delaware against the GeoMx products sold by Bruker Corporation (Nasdaq: BRKR), which acquired the product line from NanoString Technologies. To minimize the risk of disruption to ongoing research, 10x Genomics requested a carve-out for GeoMx users who installed an instrument prior to the trial in November 2023 . The injunction, which the Court said it will enter in January 2025 , is expected to prohibit Bruker from making, using, selling or offering to sell in the United States its GeoMx Digital Spatial Profiler and associated instruments, reagents and services for RNA and protein detection. At the request of 10x Genomics, the injunction will not block ongoing research by researchers who installed a GeoMx instrument prior to November 18, 2023 . Such customers can continue to purchase GeoMx reagents for use with existing GeoMx instruments for purposes of continuing their ongoing research. The Court found that making such an exception for ongoing research strikes a "workable balance between protecting the patentee's rights and protecting the public from the injunction's adverse effects." In addition, the Court affirmed the $31 million damages awarded by the November 2023 jury verdict, as well as supplemental damages and interest that will be added to the total damages when final judgment is entered. "Today's decision helps to safeguard our decade-long investment in innovation and ensures we can continue to develop groundbreaking technologies that help our customers revolutionize science," said Eric Whitaker , Chief Legal Officer at 10x Genomics. "10x exists to fuel scientific progress – not stifle it – and that is why we've done our utmost to ensure this injunction was structured to protect both our intellectual property and existing GeoMx customers' ongoing research." The Court recognized the harm NanoString's infringing conduct caused 10x when it wrote in its ruling, "Having been careful not to license its technology, 10x suffers when it proclaims itself as an innovator in spatial genomics but a competitor is using the same innovative, patented technology." Today's Court decision follows a November 2023 jury verdict that found that NanoString's GeoMx products willfully infringed seven patents exclusively licensed to 10x Genomics by Prognosys. During the trial, the jury heard testimony from the sole inventor of the patents, Illumina co-founder Mark Chee , and NanoString CEO Brad Gray and NanoString CSO Joe Beechem. After hearing all of the evidence, the jury determined that all seven patents had been infringed by NanoString, that each patent was valid, that NanoString willfully infringed those patents and that monetary damages were owed to 10x for the infringement of all seven patents. In affirming the jury's finding that NanoString willfully infringed, the Court relied on the evidence showing that NanoString knew or was willfully blind that its acts would cause infringement of 10x's rights. The asserted patents in Case No. 21-cv-653-MFK include (a) U.S. Patent No. 10,472,669; (b) U.S. Patent No. 10,961,566; (c) U.S. Patent No. 10,983,113; (d) U.S. Patent No. 10,996,219; (e) U.S. Patent No. 11,001,878; (f) U.S. Patent No. 11,008,607 and (g) U.S. Patent No. 11,293,917. About 10x Genomics 10x Genomics is a life science technology company building products to accelerate the mastery of biology and advance human health. Our integrated solutions include instruments, consumables and software for single cell and spatial biology, which help academic and translational researchers and biopharmaceutical companies understand biological systems at a resolution and scale that matches the complexity of biology. Our products are behind breakthroughs in oncology, immunology, neuroscience and more, fueling powerful discoveries that are transforming the world's understanding of health and disease. To learn more, visit 10xgenomics.com or connect with us on LinkedIn or X (Twitter) . Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 as contained in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the "safe harbor" created by those sections. All statements included in this press release, other than statements of historical facts, may be forward-looking statements. Forward-looking statements generally can be identified by the use of forward-looking terminology such as "may," "might," "will," "should," "expect," "plan," "anticipate," "could," "intend," "target," "project," "contemplate," "believe," "see," "estimate," "predict," "potential," "would," "likely," "seek" or "continue" or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include statements regarding litigation and remedies as well as possible outcomes of litigation. These forward-looking statements do not reflect that our success will depend on our ability to obtain, maintain and protect our intellectual property rights, intellectual property litigation could be expensive, time-consuming, unsuccessful and could interfere with our ability to develop, manufacture and commercialize our products or technologies, litigation outcomes are unpredictable or there may be changes in our litigation strategy. These statements are based on management's current expectations, forecasts, beliefs, assumptions and information currently available to management. Actual outcomes and results could differ materially from these statements due to a number of factors and such statements should not be relied upon as representing 10x Genomics, Inc.'s views as of any date subsequent to the date of this press release. 10x Genomics, Inc. disclaims any obligation to update any forward-looking statements provided to reflect any change in 10x Genomics' expectations or any change in events, conditions or circumstances on which any such statement is based, except as required by law. The material risks and uncertainties that could affect 10x Genomics, Inc.'s financial and operating results and cause actual results to differ materially from those indicated by the forward-looking statements made in this press release include those discussed under the captions "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" in the company's most recently-filed 10-K for the fiscal year ended December 31, 2023 and elsewhere in the documents 10x Genomics, Inc. files with the Securities and Exchange Commission from time to time. Disclosure Information 10x Genomics uses filings with the Securities and Exchange Commission, our website ( www.10xgenomics.com ), press releases, public conference calls, public webcasts and our social media accounts as means of disclosing material non-public information and for complying with our disclosure obligations under Regulation FD. Contacts Investors: investors@10xgenomics.com Media: media@10xgenomics.com View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-awards-10x-genomics-permanent-injunction-in-patent-infringement-lawsuit-against-bruker-corporations-geomx-products-302338627.html SOURCE 10x Genomics, Inc.
Bali Nine members could continue sentences in Australia
Eddie Lampkin and Donnie Freeman both turned in double-double performances as Syracuse snapped a two-game losing streak with a 75-63 win over Bucknell Saturday at the JMA Wireless Dome in Syracuse, N.Y. Lampkin scored 18 points and grabbed 11 rebounds while Freeman finished with 15 points and 11 boards as the Orange (6-6) improved to 11-1 all-time against the Bison (4-9). Jaquan Carlos chipped in 11 for Syracuse. Josh Bascoe was impressive in defeat, knocking down six 3-pointers and scoring 22 in all. Noah Williamson added 12 for the Bison, who dropped their seventh in a row but didn't go away quietly. Trailing 43-31 at the half, the Bison pulled within 48-43 after a dunk by Pip Ajayi with 14:13 left. That was as close as Bucknell would get, however, as it fell short in its bid for its first win over a power conference team since beating Vanderbilt 75-72 victory during the 2016-17 campaign. In the final nonleague game for both teams, Syracuse shook off a slow start with a 9-0 run ignited by a Lucas Taylor 3-pointer and capped with a layup by Freeman that put the Orange up 12-6 with 14:30 to go. The Orange led 17-12 with 11:23 to go after a 3-pointer by Elijah Moore, but back-to-back 3-pointers by Jayden Williams and Bascoe put the Bison on top 21-19 with 8:04 remaining. With Bucknell up 26-22, momentum shifted in Syracuse's favor on the strength of a 16-2 run, highlighted by Freeman's 3-pointer that gave the Orange their first double-digit lead at 38-28 with 1:49 to play in the half. Freeman hit another shot from distance with seven seconds left, shooting over a defender from well beyond the line and extending the lead to 43-31. He high-fived teammates as he came off the court. His bucket was one of six 3-pointers Syracuse connected on in the opening half while shooting 57.6 percent (17-of-30) from the field. The Orange outscored the Bison 18-3 over the final 5:39, limiting Bucknell to only one field goal. --Field Level Media
It’s official: Justin Trudeau has finally given up on being the prime minister of Canada. There have been plenty of previous warning signs. During the NAFTA renegotiations, for instance, Trudeau pressed the United States and Mexico to include progressive concepts like gender rights and Indigenous rights, which have nothing to do with free trade. His ignorance of the nuances of the job was on full display in 2021, when he said, “You’ll forgive me if I don’t think about monetary policy.” And his decision to go surfing in Tofino, B.C., during the first National Day for Truth and Reconciliation in 2021 showed his complete disinterest in national leadership. What Trudeau recently said about U.S. president-elect Donald Trump, the U.S. election and feminism proves that he’s shifted from a lame-duck to a dead-duck prime minister. On Tuesday evening, Trudeau spoke at an event hosted by the Equal Voice Foundation, a “registered charity dedicated to improving gender representation in Canadian politics,” according to its website. He clearly decided that this was the perfect venue to spout off several buckets of drivel about Trump and the U.S. election to a largely like-minded audience. “Just a few weeks ago, the United States voted for a second time to not elect its first woman president,” he said at the Equal Voice Gala Marking International Human Rights Day in Ottawa. “Everywhere, women’s rights and women’s progress is under attack. Overtly, and subtly. But I want you to know that I am, and always will be, a proud feminist. You will always have an ally in me and in my government.” These lines perfectly define Trudeau’s nine years as prime minister: divisive and delusional. Let’s start with his decision to keep calling himself a feminist. That’s pretty rich, all things considered. Two former senior cabinet ministers, Jody Wilson-Raybould and Jane Philpott, would likely disagree based on their experiences in pushing back against the prime minister during the SNC-Lavalin affair. Celina Caesar-Chavannes, Trudeau’s former parliamentary secretary, would also likely disagree based on the “hostility” and “anger” she reportedly faced in private conversations with him. Ruth Ellen Brosseau, a former NDP MP who he bumped into during a May 2016 parliamentary session, in what came to be known as “Elbowgate,” might like a word, too. Meanwhile, over half of eligible American voters didn’t decide not to elect its first female president. They decided that Democratic presidential candidate Kamala Harris was a lousy choice who lacked the political knowledge, policy understanding and horse sense to lead the country. Trump may have his faults, but as I wrote in these pages recently, he’s a “far more competent political leader on his worst day than Harris would ever be on her best.” Also, when has Canada ever elected a female prime minister? The only woman to hold the position, Kim Campbell, was chosen by delegates at the Progressive Conservative leadership convention in 1993. It appears that Trudeau has a selective memory — or no memory at all. Returning to Trump, it’s fair to say that Trudeau’s comment was his mealymouthed way of countering the president-elect’s recent trolling efforts. This goes back to their Nov. 29 dinner meeting at Mar-a-Lago in Florida. Trudeau reportedly told Trump that his proposed 25 per cent tariff on all Canadian goods would destroy Canada’s economy. Trump then jokingly said that Canada could become the 51st state, with Trudeau serving as its governor. Trump continued to tease Trudeau in the days that followed. There was the widely viewed Dec. 3 meme that Trump posted to Truth Social of an AI-generated image of him standing on a mountain next to a Canadian flag, with the words, “Oh Canada!” On Tuesday, he called Trudeau “governor” and Canada a “great state.” Trudeau’s decision to push back by lamenting the results of the U.S. election may have given him some pleasure in private, but it was an extraordinarily stupid move to make in public. Trump, like most world leaders, knows this prime minister is weak and ineffective. He didn’t have much respect for Trudeau to begin with, and this indirect jab probably eliminated what little he had left. In the midst of difficult discussions about forthcoming tariffs that could potentially hurt both countries’ economies, it is beyond comprehension that the prime minister would choose to poke the presidential bear. That’s not the way to save us from Trump, which Trudeau claims only he can accomplish. No one is suggesting the prime minister should lay down and give in to every demand that Trump makes. Then again, Trump makes some fair points about this government’s lack of commitment to border security and national defence. This is the perfect opportunity to implement much-needed reforms. If Canadian goods end up getting hit with a 25 per cent tariffs, it will be due to Trudeau’s decision to have seemingly given up on being our leader. What a disgrace. National PostBAKU, Azerbaijan (AP) — In the wee hours Sunday at the United Nations climate talks, countries from around the world reached an agreement on how rich countries can cough up the funds to support poor countries in the face of climate change. It's a far-from-perfect arrangement, with many parties still unsatisfied but some hopeful that the deal will be a step in the right direction. World Resources Institute president and CEO Ani Dasgupta called it “an important down payment toward a safer, more equitable future,” but added that the poorest and most vulnerable nations are “rightfully disappointed that wealthier countries didn’t put more money on the table when billions of people’s lives are at stake.” The summit was supposed to end on Friday evening but negotiations spiraled on through early Sunday. With countries on opposite ends of a massive chasm, tensions ran high as delegations tried to close the gap in expectations. Here's how they got there: What was the finance deal agreed at climate talks? Rich countries have agreed to pool together at least $300 billion a year by 2035. It’s not near the full amount of $1.3 trillion that developing countries were asking for, and that experts said was needed. But some delegations said this deal is headed in the right direction, with hopes that more money flows in the future. The text included a call for all parties to work together using “all public and private sources” to get closer to the $1.3 trillion per year goal by 2035. That means also pushing for international mega-banks, funded by taxpayer dollars, to help foot the bill. And it means, hopefully, that companies and private investors will follow suit on channeling cash toward climate action. The agreement is also a critical step toward helping countries on the receiving end create more ambitious targets to limit or cut emissions of heat-trapping gases that are due early next year. It’s part of the plan to keep cutting pollution with new targets every five years, which the world agreed to at the U.N. talks in Paris in 2015. The Paris agreement set the system of regular ratcheting up climate fighting ambition as away to keep warming under 1.5 degrees Celsius (2.7 degrees Fahrenheit) above pre-industrial levels. The world is already at 1.3 degrees Celsius (2.3 degrees Fahrenheit) and carbon emissions keep rising. What will the money be spent on? The deal decided in Baku replaces a previous agreement from 15 years ago that charged rich nations $100 billion a year to help the developing world with climate finance. The new number has similar aims: it will go toward the developing world's long laundry list of to-dos to prepare for a warming world and keep it from getting hotter. That includes paying for the transition to clean energy and away from fossil fuels. Countries need funds to build up the infrastructure needed to deploy technologies like wind and solar power on a large scale. Communities hard-hit by extreme weather also want money to adapt and prepare for events like floods, typhoons and fires. Funds could go toward improving farming practices to make them more resilient to weather extremes, to building houses differently with storms in mind, to helping people move from the hardest-hit areas and to help leaders improve emergency plans and aid in the wake of disasters. The Philippines, for example, has been hammered by six major storms in less than a month , bringing to millions of people howling wind, massive storm surges and catastrophic damage to residences, infrastructure and farmland. “Family farmers need to be financed," said Esther Penunia of the Asian Farmers Association. She described how many have already had to deal with millions of dollars of storm damage, some of which includes trees that won't again bear fruit for months or years, or animals that die, wiping out a main source of income. “If you think of a rice farmer who depends on his or her one hectare farm, rice land, ducks, chickens, vegetables, and it was inundated, there was nothing to harvest,” she said. Why was it so hard to get a deal? Election results around the world that herald a change in climate leadership, a few key players with motive to stall the talks and a disorganized host country all led to a final crunch that left few happy with a flawed compromise. The ending of COP29 is "reflective of the harder geopolitical terrain the world finds itself in,” said Li Shuo of the Asia Society. He cited Trump's recent victory in the US — with his promises to pull the country out of the Paris Agreement — as one reason why the relationship between China and the EU will be more consequential for global climate politics moving forward. Developing nations also faced some difficulties agreeing in the final hours, with one Latin American delegation member saying that their group didn't feel properly consulted when small island states had last-minute meetings to try to break through to a deal. Negotiators from across the developing world took different tacks on the deal until they finally agreed to compromise. Meanwhile, activists ramped up the pressure: many urged negotiators to stay strong and asserted that no deal would be better than a bad deal. But ultimately the desire for a deal won out. Some also pointed to the host country as a reason for the struggle. Mohamed Adow, director of climate and energy think tank Power Shift Africa, said Friday that “this COP presidency is one of the worst in recent memory,” calling it “one of the most poorly led and chaotic COP meetings ever.” The presidency said in a statement, “Every hour of the day, we have pulled people together. Every inch of the way, we have pushed for the highest common denominator. We have faced geopolitical headwinds and made every effort to be an honest broker for all sides.” Shuo retains hope that the opportunities offered by a green economy “make inaction self-defeating” for countries around the world, regardless of their stance on the decision. But it remains to be seen whether the UN talks can deliver more ambition next year. In the meantime, “this COP process needs to recover from Baku,” Shuo said. ___ Associated Press reporters Seth Borenstein and Sibi Arasu contributed to this report. ___ The Associated Press’ climate and environmental coverage receives financial support from multiple private foundations. AP is solely responsible for all content. Find AP’s standards for working with philanthropies, a list of supporters and funded coverage areas at AP.org . Melina Walling, The Associated Press
Georgia police fire tear gas, water cannons at pro-EU protesters
Land rights hearing: Marginalised vent ire before Medha Patkar-headed panel in ChennaiLouisiana lawmakers pass income and corporate tax cuts, raising statewide sales tax to pay for itMichael Daniel has developed an app aimed at bridging the communication gap for people with . or signup to continue reading It's called the NeuroTranslator, and it quickly achieved viral status when it was launched online in November. The 34-year-old father of three from Newcastle only recently discovered that he was autistic. The diagnosis was life-changing. "My journey toward understanding that I was autistic started with my eldest daughter. As she grew into toddlerhood, I noticed certain unique traits and behaviours that felt extremely familiar - things I distinctly remembered doing myself as a child," he explains. "About a year ago, a family friend gently suggested that my daughter might be autistic. I didn't think too much about it at the time, but one day, while visiting the local library, I came across by Jenara Nerenberg. I picked it up, thinking it might offer some helpful parenting insights for my wife and I. "That night, after everyone was asleep, I stayed up reading. As I turned the pages, I felt a wave of emotion wash over me. Every story, every experience described, resonated so deeply. "I got goosebumps all over my body as it felt like the pieces of my life all fell into place. In that quiet moment by myself, I realised - I'm autistic. It was a life-changing realisation that helped me better understand myself." Looking back at his life through a different lens explained so much. "Being autistic means having a brain that's wired differently, so it has shaped literally every decision I've made throughout my life, often in ways I didn't fully understand," Daniel says. "Growing up, I always sensed that I thought differently, but society isn't always accepting of those who don't fit the norm. In response, I subconsciously developed what's known as a 'mask' - adopting behaviours that felt more socially acceptable to blend in and gain acceptance. "This experience is common among autistic individuals, especially those who don't fit the narrow, stereotypical portrayals often seen in media (think Sheldon Cooper from ). But autism is highly individual." He quotes a saying - "If you've met one autistic person, you've met one autistic person" - which he says explains how autistic traits vary, sometimes dramatically, from person to person. "After discovering that I was autistic, it felt like the process of unmasking kicked in automatically. I was eager to find the 'real me'," Daniel says. "What I didn't expect was that my brain would seemingly shut off in some areas, and I'd lose skills that had always felt second nature. It was as if the mask I had worn for years to navigate life had come off - but what lay beneath felt unfamiliar, even to me." It was a tumultuous time for the Daniel family. "I didn't recognise myself, and neither did my wife. We found ourselves speaking completely different languages, trapped in a cycle of constant misunderstandings," he says. "I'd say something with a completely different intention to how it was interpreted. Every misunderstanding seemed to trigger more emotional pain, creating a rift in our marriage that at times felt impossible to bridge. "It was that pain that drove me to create my own AI assistant. I needed something that could get me out of my own head and help me process interactions I didn't fully understand, especially in emotionally charged situations. "The AI became a lifeline, helping me break down and work through what would've taken me days to process on my own." An incident at his workplace was the final straw. In a Zoom meeting, his employer told him that the company no longer needed a full-time data analyst and that he was being "let go". "I completely misread the situation," Daniel says. "I didn't pick up on the seriousness in his facial expressions and, thinking he was joking, I burst out laughing. A moment later, HR joined the call, and that's when it hit me. It wasn't a joke. It was one of the most awkward moments of my life. "After the meeting, still reeling, I decided to release the AI tool I'd built for myself publicly for free. I thought, 'I can't be the only one going through this and if it helps even two or three people like me, that would be something good to come out of it'. "I spent the rest of the day building a simple website and posted about it on Reddit before going to bed. The next morning, I woke up to my phone blowing up with notifications. It had gone viral on Reddit and TikTok overnight, racking up hundreds of thousands of views." The app's web version had been viewed more than 400,000 times on TikTok and Reddit in the first 24 hours. There was a market for the app, but the cost was prohibitive. It was going to set Daniel back $300 a day to keep the app up and running, so he introduced "a small paywall to help cover the costs, and created a $2 per month financial hardship option for anyone struggling", while offering a slightly higher tier for people who wanted to support him as "a now-unemployed solopreneur". What started as a personal project had evolved into something much bigger. People started asking him if NeuroTranslator could be developed into a mobile app, and if it could be expanded to cover other neurotypes, such as ADHD. "I wanted NeuroTranslator to be more than just a translator for autistic communication - I wanted it to bridge communication gaps for a range of neurotypes," Daniel says. "The feedback I received from thousands of users inspired me to create something truly inclusive and scalable. "At first, I explored hiring developers to build a mobile app, but the quotes I received were far beyond what I could afford - especially given that I'd just lost my job. So, I decided to take a leap and teach myself how to build the app from scratch, with a little help from AI-powered tools along the way. "It's estimated that one in five people are neurodivergent, yet the world often isn't built for us. NeuroTranslator is my attempt to change that - to offer a way for neurodivergent and neurotypical people to connect in ways they may never have thought possible." The app works, he says, by acting as a bridge between different communication styles. Users type in a scenario and the app translates it in a way that's easy for the user to understand, based on their particular neurotype. "Anyone who isn't neurotypical will tell you that communicating can sometimes feel like speaking an entirely different language," he says. "Take something as seemingly simple as 'How are you?'. For a neurotypical person, it's often just a polite greeting, not meant to be answered in detail. For an autistic person, however, it can be interpreted as a literal question requiring an honest and thorough response. "The NeuroTranslator breaks down hidden meanings, implied context and common social cues that might not be obvious to everyone. "By making subtle adjustments in how we communicate, we can reduce misunderstandings and create more meaningful connections. That's what bridging the gap really means to me - fostering understanding by translating intent, not just words, and embracing our differences." Advertisement Sign up for our newsletter to stay up to date. We care about the protection of your data. Read our . AdvertisementPolice in Georgia on Saturday fired tear gas and water cannon to disperse pro-EU protesters rallying for a ninth consecutive day against the prime minister's decision to shelve talks on joining the bloc. The Caucasus nation has been engulfed in turmoil since the governing Georgian Dream party declared that it had won a disputed October 26 election. The party's critics have accused it of creeping authoritarianism and of steering the country back towards Russia. Thousands of defiant pro-EU protesters in Georgia rallied Friday after the prime minister claimed victory in a "battle" against the opposition. Tens of thousands have taken to the streets since the election to protest against alleged electoral fraud. Fresh rallies took place across the country after Prime Minister Irakli Kobakhidze announced last week that Georgia would not hold talks on European Union membership until 2028. Police have fired tear gas and water cannon against pro-EU protests in Tbilisi and hundreds of arrests have been made, triggering outrage at home and mounting international condemnation. France, Germany and Poland condemned what they called the government's "disproportionate" use of force against protesters and opposition leaders in a joint statement Friday. On Saturday, riot police moved in with water cannon to disperse the rally outside the parliament building, making arrests as the crowd retreated a few metres (yards), an AFP reporter witnessed. Tear gas was later deployed and groups of protesters reportedly spread across the city, blocking traffic along the capital's key thoroughfare. Georgia's rights ombudsman, Levan Ioseliani, said police "had no legal grounds for the dispersal of peaceful rally." He called on the interior ministry "to immediately halt the dispersal of the protest, cease the detention of participants, and refrain from using special measures, ensuring that protesters can continue their demonstration peacefully." Thousands blocked the street outside parliament on Friday, with some blowing whistles and others setting off firecrackers. "People will continue the protest," said one demonstrator, 23-year-old Giorgi, wearing a Georgian flag and a back scarf pulled over his nose. "They're patient, I will be here for the rest of my life if it is necessary to save my country." Separate protests were held outside Georgia's public broadcaster -- accused of being a government propaganda tool -- as well as the education ministry and the country's tourism administration offices. Thousands have also staged anti-government rallies in the second city of Batumi on the Black Sea coast. On Friday, a court in Tbilisi put a 19-year-old youth activist in pre-trial detention on charges of "organising, leading, and participating in group violence". Zviad Tsetskhladze told the judge "the rule of law has been crushed. "Our actions are a form of resistance, aimed at preserving the rule of law, defending democracy, and protecting the rights of every individual." The prime minister on Friday praised his security forces for "successfully neutralising the protesters' capacity for violence". "We have won an important battle against liberal fascism in our country," he told a news conference, using language reminiscent of how the Kremlin in Russia targets its political opponents. "But the fight is not over. Liberal fascism in Georgia must be defeated entirely," Kobakhidze said. With both sides ruling out a compromise, there appeared to be no clear route out of the crisis. The leader of the opposition Lelo party, Mamuka Khazaradze, said the government "has resorted to arresting young activists and political opponents out of fear of relentless public protests and growing civil disobedience by public servants." Masked officers have raided several opposition party offices and arrested opposition leaders earlier this week, while around 300 people have been detained at rallies. On Friday Nika Gvaramia, leader of the opposition Akhali party, was sentenced to 12 days in prison. Alexandre Elisashvili, leader of the Strong Georgia opposition group, was remanded in custody for two months of pretrial detention. More trouble is expected after December 14, when Georgian Dream lawmakers elect a loyalist to succeed pro-Western President Salome Zurabishvili. She has vowed not to step down until the parliamentary polls are re-run. Local media has also reported protests across the country, including in the cities of Batumi, Kutaisi, Zugdidi, Rustavi and Telavi. Critics of Georgian Dream are enraged by what they call its betrayal of Tbilisi's bid for EU membership, enshrined in the constitution and supported by around 80 percent of the population. Several ambassadors, a deputy foreign minister, and other officials have resigned over the suspension of EU talks. Georgian Dream, in power for more than a decade, has advanced controversial legislation in recent years, targeting civil society and independent media and curbing LGBTQ rights. Brussels warned such policies were incompatible with EU membership, while domestic critics accuse the government of copying Russia's playbook. Rights ombudsman Ioseliani has accused the police of "torture" against those arrested. ub-im/rsc Get any of our free email newsletters — news headlines, sports, arts & entertainment, state legislature, CFD news, and more.
Met Éireann weather warnings currently in place: 'Status Red warnings could still be issued for east coast' "We don't want people on the streets - at all - between 10pm and 2am during a Status Red warning" - Galway mayor Peter Keane Public transport services likely to be cancelled/curtailed during Storm Darragh Storm Darragh: Forecasters upgrade seven counties to Status Red wind warning, Bus Éireann services cancelled Bye for now Toll of Storm Darragh Wild conditions on the west coast 9pm on the dot and it went from 0 to 100 #StormDarragh has arrived in North Mayo pic.twitter.com/8FmVUGBlPf Gusts of over 140km/h now recorded Mace Head gusting up to 141kmh now at 10pm with Mayo Sailing club private station up to 148kmh. #StormDarragh pic.twitter.com/0VSoL6KrVs Large swathes of the west without power Thousands without power in the southwest due to Storm Darragh Flight diversions due to high winds ⚠️ Diversion #FR7722 / #RYR9PC from Gatwick to Cork is currently diverting to Shannon airport due to strong winds in cork #StormDarragh #aviation #avgeek #dublinairport #dublin #wind #corkairport #ireland #bert #storm #travel #goaround #diversion #corkairport #cork pic.twitter.com/jA7oGlyhk3 UK sends 'risk to life' alert to phones of over 3m people over Storm Darragh Storm Darragh about to draw near Ireland #StormDarragh is set to bring damaging winds, heavy rain, and some snow to parts of the UK and Ireland this weekend. Coastal gusts could reach 90 mph, with 60-70 mph gusts expected inland. pic.twitter.com/yqnWonrmQa Storm Darragh safety message from Gas Networks Ireland Met Éireann weather warnings currently in place: OPW warns Dublin Castle Christmas markets 'could close early' Due to Storm Darragh, Christmas at the Castle may close early this evening. On Saturday December 7th, the market will open at 1pm at the earliest, subject to the weather status. Please keep an eye on our socials & https://t.co/QgylwbOk9V for updates 📸Dublin Castle @opwireland pic.twitter.com/TxPA4cq34C Those planning "Christmas night out" advised to check local forecast and plan accordingly ❗Attention 📢Red warnings are now in place on the West & North West Coasts until 3pm tomorrow. Extremely strong and gusty northwest winds are expected. pic.twitter.com/ohNqIll1VF University of Galway to close during Red Alert hours **Weather Alert** Met Éireann have issued a Status Red wind warning for Galway and other counties from 10PM Friday, 6th December to 2AM Saturday, 7th December. University campuses in affected areas will be closed until the warning ends. If the warning is extended, the closure... pic.twitter.com/hZ58633OmS Leading homelessness organisations express 'grave concern' for asylum-seekers Assistance available to households Orange warning update Timings updated for Red warningsThree climbers missing on New Zealand peak believed dead: police
InnovationRx: What We Know About UnitedHealthcare CEO’s Alleged Killer So FarAI's next frontier: Selling your intentions before you know themPep Guardiola admits he is questioning himself after Manchester City’s latest defeat left them in danger of missing out on the Champions League knockout stages. City slumped to their seventh defeat in 10 games in all competitions as they were beaten 2-0 at Juventus in their latest European outing on Wednesday. Second-half goals from Dusan Vlahovic and Weston McKennie at the Allianz Stadium left Guardiola’s side languishing in 22nd place in the standings. Juventus beat Man City 💪 #UCL pic.twitter.com/H4KL15iCke — UEFA Champions League (@ChampionsLeague) December 11, 2024 With just two games of the league phase remaining, a place in the top eight and automatic last-16 qualification looks beyond them and they face a battle just to stay in the top 24 and claim a play-off spot. City manager Guardiola said: “Of course I question myself but I’m stable in good moments and bad moments. “I try to find a way to do it. I’m incredibly honest. If we play good (I say) we played good and today I thought we played good. “Our game will save us. We can do it. We conceded few chances compared to the Nottingham Forest game that we won. We’re making the right tempo. “We missed the last pass, did not arrive in the six-yard box (at the right time) or have the composure at the right moment. “But I love my team. This is life, it happens. Sometimes you have a bad period but I’m going to insist until we’re there.” City now face a crunch trip to Paris St Germain, who are also at risk of failing to qualify, next month. Guardiola accepts the top 24 is now the only aim. He said: “It’s the target. We need one point or three points. We go to Paris to try to do it and the last game at home.” Veteran midfielder Ilkay Gundogan said after the game he felt City were suffering from a loss of confidence but Guardiola dismissed his player’s comments. “I am not agreeing with Ilkay,” he said. “Of course it is tough but, except one or two games in this period, we’ve played good.” City now face a further test of their resolve as they host rivals Manchester United in a derby on Sunday. "We played well" Pep Guardiola trusts in his squad despite 2-0 loss to Juventus... 📺 @tntsports & @discoveryplusUK pic.twitter.com/VrmTzcTrEF — Football on TNT Sports (@footballontnt) December 11, 2024 Gundogan told TNT Sports: “It (confidence) is a big part of it. That’s a mental issue as well. “You can see that sometimes we miss the ball or lose a duel and you see that we drop immediately and lose the rhythm. They (the opponents) don’t even need to do much but it has such a big effect on us right now. “Even more you have to do the simple things as good as possible and create and fluidity, then it’s work hard again. This is how you get confidence back – do the small and simple things, (but) in crucial moments at the moment we are always doing the wrong things.” Juventus coach Thiago Motta was pleased with the hosts’ performance, which boosted their hopes of making the top eight. “It was a deserved victory,” he said. “We had to defend as a team and be ready to attack with quality. “We have shown we can compete at this level and now we have to do it consistently.”
Lorenz scores 20, Wofford downs Kentucky Christian 100-55
AP Business SummaryBrief at 4:40 p.m. ESTSAN DIEGO , Dec. 23, 2024 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX ) ("Heron" or the "Company"), a commercial-stage biotechnology company, announced today the relocation of the Company's headquarters from San Diego, California to Cary, North Carolina , effective January 1, 2025 . A majority of Heron's Management Team and corporate employees work from the Cary office, which is near the Research Triangle Park ("RTP"), one of the most prominent high-tech research and development parks in the United States . The growing biotech community in Cary and its surrounding areas provides ample space for growth and expansion. "We are excited to move our headquarters to Cary, North Carolina , which represents a significant milestone in Heron's journey," said Craig Collard , Chief Executive Officer of Heron. "This move will not only strengthen our ability to support our employees by centralizing our operations and resources, but also positions us in an excellent location from which we can continue making strategic partnerships as we growing our existing portfolio focused on improving the lives of patients in the acute and oncology care settings. This is an exciting chapter for Heron, and we look forward to the continued success and partnerships that lie ahead." The new address for Heron's corporate headquarters is 100 Regency Forest Drive, Suite 300, Cary, NC 27518. About Heron Therapeutics, Inc. Heron Therapeutics, Inc. is a commercial-stage biotechnology company focused on improving the lives of patients by developing and commercializing therapeutic innovations that improve medical care. Our advanced science, patented technologies, and innovative approach to drug discovery and development have allowed us to create and commercialize a portfolio of products that aim to advance the standard-of-care for acute care and oncology patients. For more information, visit www.herontx.com . Forward-looking Statements This news release contains "forward-looking statements" as defined by the Private Securities Litigation Reform Act of 1995. Heron cautions readers that forward-looking statements are based on management's expectations and assumptions as of the date of this news release and are subject to certain risks and uncertainties that could cause actual results to differ materially. Therefore, you should not place undue reliance on forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in our most recent Annual Report on Form 10-K and any subsequent Quarterly Reports on Form 10-Q, and in our other reports filed with the Securities and Exchange Commission, including under the caption "Risk Factors." Forward-looking statements reflect our analysis only on their stated date, and Heron takes no obligation to update or revise these statements except as may be required by law. Investor Relations and Media Contact: Ira Duarte Executive Vice President, Chief Financial Officer Heron Therapeutics, Inc. [email protected] 858-251-4400 SOURCE Heron Therapeutics, Inc.
The recent sightings of mysterious drones over Massachusetts and the arrests of two men who allegedly flew the unmanned aircraft close to Logan Airport are leading a state lawmaker to refile legislation he says would increase accountability. State Rep. Bruce Ayers, D-Quincy, says more safeguards against “reckless behavior” are essential as drone technology increases every year, making them faster and capable of carrying significant weight with “high-powered cameras.” Ayers plans to refile two pieces of legislation at the State House in the new year, one that would impose fines and restrictions on flying drones in flight paths, near airports, and another that would target flight over schools. Boston Police responded to Long Island, part of Ayers’ district, on Dec. 14 after officials noticed a drone flying around the Boston Harbor, at a distance deemed too close to Logan Airport on their monitoring systems. Authorities charged Robert Duffy, 42, of Charlestown, and Jeremy Folcik, 32, of Bridgewater, with trespassing, breaking and entering, and violating a municipal ordinance or bylaw, in connection to flying the drones in “hazardous air space.” Dorchester District Court Judge Erika Reis ordered the defendants to stay away from the closed Long Island health campus and not operate drones , releasing them without bail. Ayers told the Herald on Saturday that he believes Duffy and Folcik should have faced harsher consequences. “We need to set a stronger precedent that if people are flying these drones recklessly, it’s no joke, it’s no harmless prank,” he said. “There are going to be consequences.” Under his act relative to air traffic safety, individuals who purposely fly drones or aim the beam of a laser pointer at an aircraft or the flight path, interfering with travel, would be punished by a fine of no more than $1,500. The punishment would increase if a “significant change of course or other serious disruption to the safe travel of an aircraft” threatened the safety of passengers or the crew. In those instances, individuals would face a fine of up to $5,000 or up to five years in state prison, or both. “That is the most dangerous time when a flight is descending, our pilots are trying to navigate the instruments and prepare to land,” Ayers said. “We need to be able to protect them.” Massport has installed more than 200 “No Drone Zone” signs around Logan Airport and other facilities, and the state Department of Conservation and Recreation prohibits flying over its properties unless authorized. Drone operators in Massachusetts don’t need a state-level permit but must follow federal regulations. Recreational drones that weigh over 0.55 pounds are required to be registered with the Federal Aviation Administration, and commercially, an FAA remote pilot certificate is required. Individuals who fly in restricted airspace and commit a federal violation could be fined up to $27,500 for civil penalties or criminal charges. Local law enforcement is unable to enforce FAA regulations. Boston Police said that the men who they arrested for flying the drones too close to Logan Airport could end up facing federal charges. Ayers added his proposed law would provide “more resources on the ground,” meaning more local and state police surrounding airports would be focused on tracking down drones to assist the feds. The other legislation that Ayers is set to refile would carry fines for flying drones within a vertical distance of 400 feet in school zones. While the reported sightings of the mysterious drones over Cape Cod and elsewhere in Massachusetts were fairly limited and have dropped during the holidays, Ayers said he’s still hearing from constituents. “People were scared, they’re concerned, and they’re frustrated,” he said. “They want to know what is going on. This would give us more resources to identify and go after people who may be doing wrongdoing, and if so, to prosecute them.” Gov. Maura Healey has also expressed concern although she admitted Massachusetts wasn’t seeing the volume of reported drones as in New York and New Jersey, and that authorities weren’t aware of a public safety threat. Healey has urged Congress to allow states to investigate and prosecute illegal activity and provide better technology to help detect drones. “The pace of technology has really evolved very quickly,” the governor told reporters on Dec. 17, “and it’s a serious concern.” The week before Christmas, the FAA banned drone flights in 22 areas in New Jersey and 30 areas in New York, mostly in and around New York City and on Long Island, where critical infrastructure is located, through mid-January. Federal authorities had said many of the sightings had been of legal drones, manned aircraft, helicopters and even stars. The feds have not identified any public safety or national security risks. “There are more than 1 million drones that are lawfully registered with the Federal Aviation Administration here in the United States,” White House national security spokesperson John Kirby said. “And there are thousands of commercial, hobbyist and law enforcement drones that are lawfully in the sky on any given day. That is the ecosystem that we are dealing with.” The Associated Press contributed to this report
By CLAIRE RUSH President-elect Donald Trump has once again suggested he wants to revert the name of North America’s tallest mountain — Alaska’s Denali — to Mount McKinley, wading into a sensitive and decades-old conflict about what the peak should be called. Related Articles National Politics | Inside the Gaetz ethics report, a trove of new details alleging payments for sex and drug use National Politics | An analyst looks ahead to how the US economy might fare under Trump National Politics | Trump again calls to buy Greenland after eyeing Canada and the Panama Canal National Politics | House Ethics Committee accuses Gaetz of ‘regularly’ paying for sex, including with 17-year-old girl National Politics | Trump wants mass deportations. For the agents removing immigrants, it’s a painstaking process Former President Barack Obama changed the official name to Denali in 2015 to reflect the traditions of Alaska Natives as well as the preference of many Alaska residents. The federal government in recent years has endeavored to change place-names considered disrespectful to Native people. “Denali” is an Athabascan word meaning “the high one” or “the great one.” A prospector in 1896 dubbed the peak “Mount McKinley” after President William McKinley, who had never been to Alaska. That name was formally recognized by the U.S. government until Obama changed it over opposition from lawmakers in McKinley’s home state of Ohio. Trump suggested in 2016 that he might undo Obama’s action, but he dropped that notion after Alaska’s senators objected. He raised it again during a rally in Phoenix on Sunday. “McKinley was a very good, maybe a great president,” Trump said Sunday. “They took his name off Mount McKinley, right? That’s what they do to people.” Once again, Trump’s suggestion drew quick opposition within Alaska. “Uh. Nope. It’s Denali,” Democratic state Sen. Scott Kawasaki posted on the social platform X Sunday night. Republican Sen. Lisa Murkowski , who for years pushed for legislation to change the name to Denali, conveyed a similar sentiment in a post of her own. “There is only one name worthy of North America’s tallest mountain: Denali — the Great One,” Murkowski wrote on X. Various tribes of Athabascan people have lived in the shadow of the 20,310-foot (6,190-meter) mountain for thousands of years. McKinley, a Republican native of Ohio who served as the 25th president, was assassinated early in his second term in 1901 in Buffalo, New York. Alaska and Ohio have been at odds over the name since at least the 1970s. Alaska had a standing request to change the name since 1975, when the legislature passed a resolution and then-Gov. Jay Hammond appealed to the federal government. Known for its majestic views, the mountain is dotted with glaciers and covered at the top with snow year-round, with powerful winds that make it difficult for the adventurous few who seek to climb it. Rush reported from Portland, Oregon.City slumped to their seventh defeat in 10 games in all competitions as they were beaten 2-0 at Juventus in their latest European outing on Wednesday. Second-half goals from Dusan Vlahovic and Weston McKennie at the Allianz Stadium left Guardiola’s side languishing in 22nd place in the standings. Juventus beat Man City 💪 #UCL pic.twitter.com/H4KL15iCke — UEFA Champions League (@ChampionsLeague) December 11, 2024 With just two games of the league phase remaining, a place in the top eight and automatic last-16 qualification looks beyond them and they face a battle just to stay in the top 24 and claim a play-off spot. City manager Guardiola said: “Of course I question myself but I’m stable in good moments and bad moments. “I try to find a way to do it. I’m incredibly honest. If we play good (I say) we played good and today I thought we played good. “Our game will save us. We can do it. We conceded few chances compared to the Nottingham Forest game that we won. We’re making the right tempo. “We missed the last pass, did not arrive in the six-yard box (at the right time) or have the composure at the right moment. “But I love my team. This is life, it happens. Sometimes you have a bad period but I’m going to insist until we’re there.” City now face a crunch trip to Paris St Germain, who are also at risk of failing to qualify, next month. Guardiola accepts the top 24 is now the only aim. He said: “It’s the target. We need one point or three points. We go to Paris to try to do it and the last game at home.” Veteran midfielder Ilkay Gundogan said after the game he felt City were suffering from a loss of confidence but Guardiola dismissed his player’s comments. “I am not agreeing with Ilkay,” he said. “Of course it is tough but, except one or two games in this period, we’ve played good.” City now face a further test of their resolve as they host rivals Manchester United in a derby on Sunday. "We played well" Pep Guardiola trusts in his squad despite 2-0 loss to Juventus... 📺 @tntsports & @discoveryplusUK pic.twitter.com/VrmTzcTrEF — Football on TNT Sports (@footballontnt) December 11, 2024 Gundogan told TNT Sports: “It (confidence) is a big part of it. That’s a mental issue as well. “You can see that sometimes we miss the ball or lose a duel and you see that we drop immediately and lose the rhythm. They (the opponents) don’t even need to do much but it has such a big effect on us right now. “Even more you have to do the simple things as good as possible and create and fluidity, then it’s work hard again. This is how you get confidence back – do the small and simple things, (but) in crucial moments at the moment we are always doing the wrong things.” Juventus coach Thiago Motta was pleased with the hosts’ performance, which boosted their hopes of making the top eight. “It was a deserved victory,” he said. “We had to defend as a team and be ready to attack with quality. “We have shown we can compete at this level and now we have to do it consistently.”